DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art8 and Prmt2

DIOPT Version :9

Sequence 1:	NP_609478.1	Gene:	Art8 / 34528	FlyBaseID:	FBgn0032329	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001020315.1	Gene:	Prmt2 / 499420	RGDID:	1565519	Length:	445	Species:	Rattus norvegicus

Alignment Length:	286	Identity:	115/286 - (40%)
Similarity:	163/286 - (56%)	Gaps:	23/286 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YFDEYENLEIHELMLKDRPRQEAYYNAILGNKDLFKDKIVMDVGAGTGILSAFCA-KAGARLVYA 68
            |||.|..|::|..||.|:||...|::.||.||:..|||:::|||.||||:|.||| .|..:.|||
  Rat   114 YFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHHARPKAVYA 178

  Fly    69 VEASNVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAEAEKVDIIVSEWMGFYLLHEGMLDSVL 133
            ||||::|.... .|:..||..:.:.|.|.:||:.|||   ||||::||||||..||.|.|::|:|
  Rat   179 VEASDMAQHTG-QLVLQNGFADTITVFQQKVEDVVLP---EKVDVLVSEWMGTCLLFEFMIESIL 239

  Fly   134 LARDKFLKEGGLLFPSECTIFVAPCSVPS------LFDDWHNVDGIKMDTFARKLRTQKSSRPEI 192
            .|||.:|||.|:::|:...:.:.|||...      ||  |.|.....:.........:..|||:.
  Rat   240 YARDAWLKEDGIIWPTTAALHLVPCSAEKDYHSKVLF--WDNAYEFNLSALKSLAIKEFFSRPKS 302

  Fly   193 TQ-LNPQDLLHEGVVFHWMNLLDVEASDLDSIQFKEVITAQKAGNHQGFCIWFDVQF-------P 249
            .. |.|:|.|.|......:::..|:.|||::::.:.....||||...||..||.|.|       |
  Rat   303 NHILKPEDCLSEPCTILQLDMRTVQVSDLETMRGELRFDIQKAGTLHGFTAWFSVHFQSLEEGQP 367

  Fly   250 GEDFVLSTSPLSPPTHWKQCVVVLPE 275
            .:  ||||.||.|.|||||.:.::.:
  Rat   368 QQ--VLSTGPLHPTTHWKQTLFMMDD 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art8	NP_609478.1	SmtA	1..244	CDD:223574	98/246 (40%)
Art8	NP_609478.1	Methyltransf_18	40..147	CDD:289607	56/107 (52%)
Prmt2	NP_001020315.1	SH3_PRMT2	46..98	CDD:212740
Prmt2	NP_001020315.1	AdoMet_MTases	153..253	CDD:100107	53/103 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352452
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D387140at33208
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750