Protein Alignment Art8 and PRMT1

DIOPT Version :10

• Sequence 1: NP_609478.1
• Gene: Art8 / 34528
• FlyBaseID: FBgn0032329
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: NP_001527.3
• Gene: PRMT1 / 3276
• HGNCID: 5187
• Length: 371
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 116/323 - (35%)
• Similarity: 170/323 - (52%)
• Gaps: 40/323 - (12%)

  Fly     5 YFDEYENLEIHELMLKDRPRQEAYYNAILGNKDLFKDKIVMDVGAGTGILSAFCAKAGARLVYAV 69
            |||.|.:..|||.||||..|...|.|::..|:.|||||:|:|||:|||||..|.||||||.|..:
Human    53 YFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGI 117

  Fly    70 EASNVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAEAEKVDIIVSEWMGFYLLHEGMLDSVLL 134
            |.|:: :..|:.:::.|.|.:||.:|:.:|||..||  .||||||:|||||:.|.:|.||::||.
Human   118 ECSSI-SDYAVKIVKANKLDHVVTIIKGKVEEVELP--VEKVDIIISEWMGYCLFYESMLNTVLY 179

  Fly   135 ARDKFLKEGGLLFPSECTIFVAPCSVPSLFDD----------WHNVDGIKMDTFARKLRTQKSSR 189
            ||||:|...||:||...|::|      :..:|          |.||.|..|..    ::......
Human   180 ARDKWLAPDGLIFPDRATLYV------TAIEDRQYKDYKIHWWENVYGFDMSC----IKDVAIKE 234

  Fly   190 PEITQLNPQDLLHEGVVFHWMNLLDVEASDLDSIQFKEVITAQKAGNH--QGFCIWFDVQF---- 248
            |.:..::|:.|:....:...:::..|:..||   .|......|...|.  .....:|:::|
Human   235 PLVDVVDPKQLVTNACLIKEVDIYTVKVEDL---TFTSPFCLQVKRNDYVHALVAYFNIEFTRCH 296

  Fly   249 --PGEDFVLSTSPLSPPTHWKQCVVVLPEESCENLEEKSPIAFQITMKRSAADMRKYNLEVDL 309
              .|    .||||.||.|||||.|..:  |....::....|...|.|:.:|.:.|..:..:||
Human   297 KRTG----FSTSPESPYTHWKQTVFYM--EDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDL 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Art8	NP_609478.1	COG4076	15..>191	CDD:443253	79/185 (43%)
PRMT1	NP_001527.3	COG4076	63..>236	CDD:443253	79/185 (43%)