DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art8 and Prmt2

DIOPT Version :9

Sequence 1:	NP_609478.1	Gene:	Art8 / 34528	FlyBaseID:	FBgn0032329	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001289894.1	Gene:	Prmt2 / 15468	MGIID:	1316652	Length:	475	Species:	Mus musculus

Alignment Length:	316	Identity:	113/316 - (35%)
Similarity:	162/316 - (51%)	Gaps:	53/316 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YFDEYENLEIHELMLKDRPRQEAYYNAILGNKDLFKDKIVMDVGAGTGILSAFCA-KAGARLVYA 68
            |||.|..|::|..||.|:||...|::.||.||:..|||:::|||.||||:|.||| .|..:.|||
Mouse   114 YFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHHARPKAVYA 178

  Fly    69 VEASNVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAEAEKVDIIVSEWMGFYLLHEGMLDSVL 133
            ||||::|...: .|:..||..:.:.|.|.:||:.|||   ||||::||||||..||.|.|::|:|
Mouse   179 VEASDMAQHTS-QLVLQNGFADTITVFQQKVEDVVLP---EKVDVLVSEWMGTCLLFEFMIESIL 239

  Fly   134 LARDKFLKEGGLLFPSECTIFVAPCSVPS------LFDDWHNVDGIKMDTFARKLRTQKSSRPEI 192
            .|||.:||..|:::|:...:.:.|||...      ||  |.|.....:.........:..|||:.
Mouse   240 YARDTWLKGDGIIWPTTAALHLVPCSAEKDYHSKVLF--WDNAYEFNLSALKSLAIKEFFSRPKS 302

  Fly   193 TQ-LNPQDLLHEGVVFHWMNLLDVEASDLDSIQFKEVITAQKAGNHQGFCIWFDVQF-------P 249
            .. |.|:|.|.|......:::..|:..||::::.:.....||||...||..||.|.|       |
Mouse   303 NHILKPEDCLSEPCTILQLDMRTVQVPDLETMRGELRFDIQKAGTLHGFTAWFSVYFQSLEEGQP 367

  Fly   250 GEDFVLSTSPLSP------------------------------PTHWKQCVVVLPE 275
            .:  ||||.||.|                              .|||||.:.::.:
Mouse   368 QQ--VLSTGPLHPFLGRTGCQCRGPRWSCQMRPVGDRMLLSCSTTHWKQTLFMMDD 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art8	NP_609478.1	SmtA	1..244	CDD:223574	96/246 (39%)
Art8	NP_609478.1	Methyltransf_18	40..147	CDD:289607	55/107 (51%)
Prmt2	NP_001289894.1	SH3_PRMT2	46..98	CDD:212740
		AdoMet_MTases	122..>181	CDD:302624	30/58 (52%)
		AdoMet_MTases	153..253	CDD:100107	52/103 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848847
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D387140at33208
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750