DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Art8 and ATPSCKMT

DIOPT Version :9

Sequence 1:NP_609478.1 Gene:Art8 / 34528 FlyBaseID:FBgn0032329 Length:341 Species:Drosophila melanogaster
Sequence 2:NP_954584.2 Gene:ATPSCKMT / 134145 HGNCID:27029 Length:233 Species:Homo sapiens


Alignment Length:147 Identity:37/147 - (25%)
Similarity:50/147 - (34%) Gaps:60/147 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    96 QSRVEEFVLPAEAEKVDIIVSEWMGFYLLHEGMLDSVLLARDKFLKEGGLLFPSECTIFVAPC-- 158
            |||   .||||..|...:..|.| ||.|  .|::...|:|           ..:..|.||.|.  
Human    17 QSR---HVLPASFEVNSLQKSNW-GFLL--TGLVGGTLVA-----------VYAVATPFVTPALR 64

  Fly   159 -----SVPSLFDDWHNVDGIKMDTFARKLRTQKSSRPEITQLNPQDLLHEGVVFHWMNLLDVEAS 218
                 .||:......||  :||      ||.::.|                       |:|:.:.
Human    65 KVCLPFVPATTKQIENV--VKM------LRCRRGS-----------------------LVDIGSG 98

  Fly   219 DLDSIQFKEVITAQKAG 235
            |     .:.||.|.|.|
Human    99 D-----GRIVIAAAKKG 110

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Art8NP_609478.1 SmtA 1..244 CDD:223574 37/147 (25%)
Methyltransf_18 40..147 CDD:289607 16/50 (32%)
ATPSCKMTNP_954584.2 Required for mitochondrial location. /evidence=ECO:0000269|PubMed:30530489 56..90 12/41 (29%)
AdoMet_MTases 83..>188 CDD:388410 13/62 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0500
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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