Protein Alignment aub and AGO1

DIOPT Version :9

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001246314.1
• Gene: AGO1 / 36544
• FlyBaseID: FBgn0262739
• Length: 984
• Species: Drosophila melanogaster
• Alignment Length: 968
• Identity: 221/968 - (22%)
• Similarity: 392/968 - (40%)
• Gaps: 204/968 - (21%)

  Fly     5 PNPVIARGRGRGRKPNNVEANRGF-----APSLGQKSDP----SHSEGNQASGGNGGGGDAQVGP 60
            |:|.      |.:.|:  :|...|     .|:.|...:|    |.|..|.|:|          |.
  Fly    46 PSPT------RPQSPS--QAQTSFDTLTSPPAPGSSVNPTAVTSPSAQNVAAG----------GA 92

  Fly    61 SIEKSSLSAVQMHKSEGDPRGSVRGRRLITDLVYSRP--PGMTSKK----GVVGTHITVQANYFK 119
            ::..::.:|.|:..:.|...|||. ..:.|....::|  |..|..:    |..|..|.::||:|:
  Fly    93 TVAGAAATAAQVASALGATTGSVT-PAIATATPATQPDMPVFTCPRRPNLGREGRPIVLRANHFQ 156

  Fly   120 VLKRPNWTIYQYRVDFTPDVEATRLRR----SFLYEHKGILGGY--IFDGTNMFCINQFKAVQDS 178
            | ..|...::.|.::..||....::.|    :.::.:..|.|..  :|||.|
  Fly   157 V-TMPRGYVHHYDINIQPDKCPRKVNREIIETMVHAYSKIFGVLKPVFDGRN------------- 207

  Fly   179 PYVLELVTKSR---AGENIEIKIKAVGS-----VQSTDAEQFQVLNLILRRAMEG---------- 225
                .|.|:..   ..|.:|:::...|.     .:.|...|.||....|..|:||
  Fly   208 ----NLYTRDPLPIGNERLELEVTLPGEGKDRIFRVTIKWQAQVSLFNLEEALEGRTRQIPYDAI 268

  Fly   226 LDLKLVSRY-------------------YYDPQAKINLENFRMQLWPGYQTSIRQHENDILLCSE 271
            |.|.:|.|:                   ||.|     |...| ::|.|:..|:|..:..::|..:
  Fly   269 LALDVVMRHLPSMTYTPVGRSFFSSPEGYYHP-----LGGGR-EVWFGFHQSVRPSQWKMMLNID 327

  Fly   272 ICHKVM-RTETLYNILSDA--IRD--------SDDYQSTFKRAVMGMVILTDY---NNKTYRIDD 322
            :..... :.:.:.:.:.:.  |||        :|..:..|.:.:.|:.|...:   ..:.||:.:
  Fly   328 VSATAFYKAQPVIDFMCEVLDIRDINEQRKPLTDSQRVKFTKEIKGLKIEITHCGQMRRKYRVCN 392

  Fly   323 V-----DFQSTPLCKFKTNDGEISYVDYYKKRYNIIIRDLKQPLVMSRPTDKNIRGGNDQAIMII 382
            |     ..||.||........|.:...|:..:|.:.:|....|.         ::.|.:.....:
  Fly   393 VTRRPAQMQSFPLQLENGQTVECTVAKYFLDKYRMKLRYPHLPC---------LQVGQEHKHTYL 448

  Fly   383 P-ELARATGMTDAMR--ADFRTLRAMSEHTRLNPDRRIERLRMFNKRLKSCKQSVET-LKSWNIE 443
            | |:.........::  .|.:|...:....|..|||.    |..|..:|....:.:: ::.:.:.
  Fly   449 PLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDRE----REINNLVKRADFNNDSYVQEFGLT 509

  Fly   444 LDSALVEIPARVLPPEKILFG--------NQKIFVCDARAD--------WTNEFRTCSMFKNVHI 492
            :.::::|:..|||||.|:.:|        .|::|....:..        |  :.|....|..|.|
  Fly   510 ISNSMMEVRGRVLPPPKLQYGGRVSTGLTGQQLFPPQNKVSLASPNQGVW--DMRGKQFFTGVEI 572

  Fly   493 NRWYV--ITPSRNLRE--TQEFVQMCIRTASSMKMNI----CNPIYEEIPDDRNGTYSQAIDNAA 549
            ..|.:  ..|.|.:||  .:.|.|...:.::...|.|    |...|...||.....:..    ..
  Fly   573 RIWAIACFAPQRTVREDALRNFTQQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRY----LK 633

  Fly   550 ANDPQIVMVVMRSPNEEK-YSCIKKRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATKVVIQMN 613
            ...|.:.:||:..|.:.. |:.:|:.......:.:|.|..|.:  .:..|..|.::..|:    |
  Fly   634 ITFPGLQLVVVVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNV--NKTSPQTLSNLCLKI----N 692

  Fly   614 AKLMGAPWQVVIPL-------HGLMTVGFDVCHSP--KNKNKSYGAFVATMDQKESFRYFSTVNE 669
            .||.|.. .:::|.       ..::.:|.||.|.|  .||..|..|.|.:||...| ||.:||..
  Fly   693 VKLGGIN-SILVPSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPS-RYAATVRV 755

  Fly   670 HIKGQELSEQM-SVNMACALRSYQEQHRSLPERILFFRDGVGDGQLYQVVNSEVNTLKD---RLD 730
            ....||:.::: |:.....:..|:......|.||:.:||||.:||...|:..|:..:::   :|:
  Fly   756 QQHRQEIIQELSSMVRELLIMFYKSTGGYKPHRIILYRDGVSEGQFPHVLQHELTAIREACIKLE 820

  Fly   731 EIYKSAGKQEGCRMTFIIVSKRINSRYF-------TGHRNPVP-GTVVDDVITLPERYDFFLVSQ 787
            ..|:..       :|||:|.||.::|.|       :|....:| ||.||..||.|..:||:|.|.
  Fly   821 PEYRPG-------ITFIVVQKRHHTRLFCAEKKEQSGKSGNIPAGTTVDVGITHPTEFDFYLCSH 878

  Fly   788 AVRIGTVSPTSYNVISDNMGLNADKLQMLSYKMTHMYYNYSGTIRVPAVCHYAHKLAF 845
            ....||..|:.|:|:.|:...::|:||.|:|::.|.|...:.::.:||..:|||.:||
  Fly   879 QGIQGTSRPSHYHVLWDDNHFDSDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 936

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	ArgoN	105..219	CDD:293095	27/127 (21%)
		PAZ_piwi_like	272..392	CDD:239211	22/139 (16%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	128/493 (26%)
AGO1	NP_001246314.1	ArgoN	146..275	CDD:406799	31/146 (21%)
		ArgoL1	285..335	CDD:400854	10/55 (18%)
		PAZ_argonaute_like	336..456	CDD:239212	22/128 (17%)
		Piwi_ago-like	502..942	CDD:240015	120/456 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910