Protein Alignment aub and Piwil1

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_017453899.1
• Gene: Piwil1 / 363912
• RGDID: 1306980
• Length: 863
• Species: Rattus norvegicus
• Alignment Length: 885
• Identity: 325/885 - (36%)
• Similarity: 498/885 - (56%)
• Gaps: 56/885 - (6%)

  Fly    10 ARGRGRGRKPNNVE--------ANRGFAPSLGQKSDPSHSE----GNQAS---GGNGGGGDAQVG 59
            ||.|||.|....|:        ...|:.|...|:| |:..:    |.|..   |......:.|:.
  Rat     7 ARARGRARGQETVQHVGAAAQSQQPGYIPPRPQQS-PTEGDLVGRGRQRGMVVGATSKSQELQIS 70

  Fly    60 PSIEKSSLSAVQMHKSEGDPRGSVRGRRLITDLVYSRPPGM----TSKKGVVGTHITVQANYFKV 120
            ...::.||:          .||.  .||...||..:....:    .||.|..|..:.:..|:|::
  Rat    71 AGFQELSLA----------ERGG--RRRDFHDLGVNTRQNLDHVKESKTGSSGIIVKLSTNHFRL 123

  Fly   121 LKRPNWTIYQYRVDFTPDVEATRLRRSFLYEHKGILGG-YIFDGTNMFCINQFKAVQDSPYVLEL 184
            ..||.|.:|||.:|:.|.:||.|||.:.|::|:.::|. :.||||.:|..   |.:|..  |.|:
  Rat   124 TSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGRCHAFDGTILFLP---KRLQHK--VTEV 183

  Fly   185 VTKSRAGENIEIKIKAVGSVQSTDAEQFQVLNLILRRAMEGLDLKLVSRYYYDPQAKINLENFRM 249
            .:::|.||::.|.|.....:..|.....|..|:|.||.::.::|:.:.|.||:|...|::.|.|:
  Rat   184 FSQTRNGEHVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPSDPIDIPNHRL 248

  Fly   250 QLWPGYQTSIRQHENDILLCSEICHKVMRTETLYNILSDAIRDSDD--YQSTFKRAVMGMVILTD 312
            .:|||:.|||.|:||:|:||:::.|||:|:||:.:.:.:..:.:::  :|....:.::|:::||.
  Rat   249 VIWPGFTTSILQYENNIMLCTDVSHKVLRSETVLDFMFNLYQQTEEHKFQEQVSKELIGLIVLTK 313

  Fly   313 YNNKTYRIDDVDFQSTPLCKFKTNDG-EISYVDYYKKRYNIIIRDLKQPLVMSRPTDKNIRGGN- 375
            |||||||:||:|:...|...||..|| |:|:::||:|:||..|.|||||:::|:|..:...||.
  Rat   314 YNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTL 378

  Fly   376 DQAIMIIPELARATGMTDAMRADFRTLRAMSEHTRLNPDRRIERLRMFNKRLKSCKQSVETLKSW 440
            ....|:||||...||:||.||.||..::.::.||||.|::|...:......:.........|:.|
  Rat   379 PGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKDDNVQRELRDW 443

  Fly   441 NIELDSALVEIPARVLPPEKILFGNQKIFVCDARADWTNEFRTCSMFKNVHINRWYVITPSRNLR 505
            .:..||.|:....|:|..|||..|.:........|||:.|.|...:.....::.|.:|...||..
  Rat   444 GLSFDSNLLSFSGRILQSEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYE 508

  Fly   506 ETQEFVQMCIRTASSMKMNICNPIYEEIPDDRNGTYSQAIDNAAANDPQIVMVVMRSPNEEKYSC 570
            .....:|...:...:|.:.:...|..|: |||...|.:|:.....:|.|||:.::.|..::||..
  Rat   509 AANSLIQNLFKVTPAMGIQMKKAIMIEV-DDRTEAYLRALQQKVTSDTQIVVCLLSSNRKDKYDA 572

  Fly   571 IKKRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATKVVIQMNAKLMGAPWQVVIPLHGLMTVGF 635
            |||..|.|.|.|||.|..:.:..:|.    :|:||||:.:|||.|:.|..|:|.:||...|.||.
  Rat   573 IKKYLCTDCPTPSQCVVARTLGKQQT----VMAIATKIALQMNCKMGGELWRVDMPLKLAMIVGI 633

  Fly   636 DVCHSPKNKNKSYGAFVATMDQKESFRYFSTVNEHIKGQELSEQMSVNMACALRSYQEQHRSLPE 700
            |..|......:|...|||::::..: |:||......:||||.:.:.|.:..|||::...:..:|.
  Rat   634 DCYHDTTAGRRSIAGFVASINEGMT-RWFSRCVFQDRGQELVDGLKVCLQAALRAWSGCNEYMPS 697

  Fly   701 RILFFRDGVGDGQLYQVVNSEVNTLKDRLDEIYKSAGKQEGCRMTFIIVSKRINSRYF--TGHR- 762
            |::.:|||||||||..:||.||....|.|    ||.|:....|:|.|:|.||:|:|:|  :|.|
  Rat   698 RVIVYRDGVGDGQLKTLVNYEVPQFLDCL----KSVGRGYNPRLTVIVVKKRVNARFFAQSGGRL 758

  Fly   763 -NPVPGTVVDDVITLPERYDFFLVSQAVRIGTVSPTSYNVISDNMGLNADKLQMLSYKMTHMYYN 826
             ||:||||:|..:|.||.||||:||||||.|:||||.||||.|:.||..|.:|.|:||:.|:|||
  Rat   759 QNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDSSGLKPDHIQRLTYKLCHVYYN 823

  Fly   827 YSGTIRVPAVCHYAHKLAFLVAESINRAPSAGLQNQLYFL 866
            :.|.|||||.|.|||||||||.:||:|.|:..|.|:||:|
  Rat   824 WPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	49/123 (40%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	175/452 (39%)
Piwil1	XP_017453899.1	GAGE	16..108	CDD:461753	20/104 (19%)
		ArgoL1	230..277	CDD:462567	22/46 (48%)
		PAZ	279..417	CDD:198017	55/137 (40%)
		Piwi_piwi-like_Euk	403..846	CDD:240016	175/452 (39%)