Protein Alignment aub and AGO3

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001036627.2
• Gene: AGO3 / 3355150
• FlyBaseID: FBgn0250816
• Length: 867
• Species: Drosophila melanogaster
• Alignment Length: 864
• Identity: 272/864 - (31%)
• Similarity: 455/864 - (52%)
• Gaps: 77/864 - (8%)

  Fly    21 NVEANRGFAPSLGQKSDPSHSEGNQASGGNGGGGDAQVGPSIEKSSLSAVQMHKSEGDPRGSVRG 85
            |:...||.|..:.......|:..             |...|..|.:::    .|::|....::..
  Fly    63 NISVGRGRARLIDTLKTDDHTSN-------------QFITSESKENIT----KKTKGPESEAIAS 110

  Fly    86 RR--LITDLVYSRPPGMTSKKGVVGTHITVQANYFKVLKRPNWTIYQYRVDFTPDVEATRLRRSF 148
            ..  ...||:|          |..|:.:.:..||.|:....:..::.|.|.|.|.:::..||..:
  Fly   111 ENGLFFPDLIY----------GSKGSSVNIYCNYLKLTTDESKGVFNYEVRFFPPIDSVHLRIKY 165

  Fly   149 LYEHKGILGG-YIFDGTNMFCINQFKAVQDSPYVLE---LVTKSRAGENIEIKIKAVGSVQSTDA 209
            |.:||..||| ..|||..::.          |.:|.   .|..|:| |::|::|:.:...:....
  Fly   166 LNDHKDKLGGTKTFDGNTLYL----------PILLPNKMTVFISKA-EDVELQIRILYKKKEEMR 219

  Fly   210 EQFQVLNLILRRAMEGLDLKLVSRYYYDPQAKINLENFRMQLWPGYQTSIRQHENDILLCSEICH 274
            ...|:.|::..|.|:.|:.....|..:||.....:...::::||||.|::.:::..::||.::.|
  Fly   220 NCTQLYNILFDRVMKVLNYVKFDRKQFDPSRPKIIPLAKLEVWPGYVTAVDEYKGGLMLCCDVSH 284

  Fly   275 KVMRTETLYNILSDAIRDS-DDYQSTFKRAVMGMVILTDYNNKTYRIDDVDFQSTPLCKFKTNDG 338
            :::..:|:..:|.|..:.: :.||.:.::.::|.::||.|||:||:|:|:.|...|.|:|:...|
  Fly   285 RILCQKTVLEMLVDLYQQNVEHYQESARKMLVGNIVLTRYNNRTYKINDICFDQNPTCQFEIKTG 349

  Fly   339 EISYVDYYKKRYNIIIRDLKQPLVMSRPTDKNIRGGNDQ-AIMIIPELARATGMTDAMRADFRTL 402
            ..|||:|||:.:||.|:|:.|||:.|....:.|....:. ...:||||...||:.|.:|:|.:.:
  Fly   350 CTSYVEYYKQYHNINIKDVNQPLIYSIKKSRGIPAERENLQFCLIPELCYLTGLRDEVRSDNKLM 414

  Fly   403 RAMSEHTRLNPDRRIERLRMFNKRLKSCKQSVETLKSWNIELDSALVEIPARVLPPEKILFGNQK 467
            |.::..||::|::|...|..|.:.:.:...:.|.|.||.:.|.:...:|..|.:..|:|.|  .|
  Fly   415 REIATFTRVSPNQRQMALNKFYENVSNTPAAQEILNSWGLSLTNNSNKISGRQMDIEQIYF--SK 477

  Fly   468 IFVCDAR-ADWTNEFRTCSMFKNVHINRWYVITPSRNLRET-----QEFVQMCIRTASSMKMNIC 526
            |.|...| |:::....|..|.|.||:::| :|...||.|:.     ....|.|    .|:.|||.
  Fly   478 ISVSAGRSAEFSKHAVTNEMLKVVHLSKW-IIIHLRNYRQAATSLLDNMKQAC----ESLGMNIS 537

  Fly   527 NPIYEEIPDDRNGTYSQAIDNAAANDPQIVMVVMRSPNEEKYSCIKKRTCVDRPVPSQVVTLKVI 591
            ||....:..||...|.||:......:.|:|:.:..:..:::|:.|||..|.:.|:||||:..|.:
  Fly   538 NPTMISLDHDRIDAYIQALRRNITMNTQMVVCICHNRRDDRYAAIKKICCSEIPIPSQVINAKTL 602

  Fly   592 APRQQKPTGLMSIATKVVIQMNAKLMGAPWQVVIPLHGLMTVGFDVCHSPKNKNKSYGAFVATMD 656
                |....:.|:..|:|:|||.||.|:.|.|.||...:|..|.|..|.|.|:..|..||||:::
  Fly   603 ----QNDLKIRSVVQKIVLQMNCKLGGSLWTVKIPFKNVMICGIDSYHDPSNRGNSVAAFVASIN 663

  Fly   657 QKESFRYFSTVNEHIKGQELSEQMSVNMACALRSYQEQHRSLPERILFFRDGVGDGQLYQVVNSE 721
            ...| :::|......|.:|:...:|.:...||:.|::::..||..|:.:|||:||||||..:|.|
  Fly   664 SSYS-QWYSKAVVQTKREEIVNGLSASFEIALKMYRKRNGKLPTNIIIYRDGIGDGQLYTCLNYE 727

  Fly   722 VNTLKDRLDEIYKSAGKQEGCRMTFIIVSKRINSRYFTGH----RNPVPGTVVDDVITLPERYDF 782
            :       .:.....|.:  .::::|:|.||||:|.|:|.    .||:||||||..||....|||
  Fly   728 I-------PQFEMVCGNR--IKISYIVVQKRINTRIFSGSGIHLENPLPGTVVDQHITKSNMYDF 783

  Fly   783 FLVSQAVRIGTVSPTSYNVISDNMGLNADKLQMLSYKMTHMYYNYSGTIRVPAVCHYAHKLAFLV 847
            |||||.||.|||:||.|.|:.|:.....|.:|.||||:..:|||::||:|:||.|.||||||:|:
  Fly   784 FLVSQLVRQGTVTPTHYVVLRDDCNYGPDIIQKLSYKLCFLYYNWAGTVRIPACCMYAHKLAYLI 848

  Fly   848 AESINRAPSAGLQNQLYFL 866
            .:||.|..:..|..:|::|
  Fly   849 GQSIQRDVAEALSEKLFYL 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	42/121 (35%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	165/458 (36%)
AGO3	NP_001036627.2	PAZ	291..425	CDD:198017	47/133 (35%)
		Piwi_piwi-like_Euk	412..850	CDD:240016	165/458 (36%)