Protein Alignment aub and Ago3

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001258122.1
• Gene: Ago3 / 313593
• RGDID: 1309163
• Length: 860
• Species: Rattus norvegicus
• Alignment Length: 847
• Identity: 190/847 - (22%)
• Similarity: 349/847 - (41%)
• Gaps: 142/847 - (16%)

  Fly    92 LVYSRPPGMTSKKGVVGTHITVQANYFKVLKRPNWTIYQYRVDFTPDVEATRLRR----SFLYEH 152
            |:..|.||.    |.:|..|.:.||.|:| :.|...:|.|.||..||....|:.|    |.:...
  Rat    15 LIVPRRPGY----GTMGKPIKLLANCFQV-EIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHF 74

  Fly   153 KGILGG---YIFDG-TNMFCINQFKAVQDSPYVLELVTKSRAGEN--IEIKIKAVGSVQ------ 205
            |..:.|   .::|| .:::..|.. .|..:...|::......|::  .::.:|.|..|.
  Rat    75 KVTIFGDRRPVYDGKRSLYTANPL-PVATTGVDLDVTLPGEGGKDRPFKVSVKFVSRVSWHLLHE 138

  Fly   206 ----STDAEQFQVLNLILRRAMEGLDLKL----------VSRYYYD-PQAKINLENFRMQLWPGY 255
                .|..|..::...|....:..:|:.|          |.|.::. |:...:......::|.|:
  Rat   139 VLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGF 203

  Fly   256 QTSIRQHENDILL-----------CSEICHKVMRTETLYNILSDAIRDSDDYQSTFKRAVMGMVI 309
            ..|:|.....::|           ...:...:.....::||.......:|.::..|.:.:.|:.:
  Rat   204 HQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKV 268

  Fly   310 LTDY---NNKTYRIDDV-----DFQSTPLCKFKTNDGEISYVDYYKKRYNIIIRDLKQPLVMSRP 366
            ...:   ..:.||:.:|     ..|:.||........|.:...|::::|.:   .||.|.:..
  Rat   269 EVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTL---QLKYPHLPC-- 328

  Fly   367 TDKNIRGGNDQAIMIIP-ELARATGMTDAMR--ADFRTLRAMSEHTRLNPDRRIERLRMFNKRLK 428
                ::.|.:|....:| |:.........::  .|.:|...:....|..|||:.|..|:    ::
  Rat   329 ----LQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRL----VR 385

  Fly   429 SCKQSVET-LKSWNIELDSALVEIPARVLPPEKILFGNQ-KIFVCDARADWTNEFRTCSMFKNVH 491
            |.....:. ::.:..::...:..:..||||...:.:|.: :.....:...|  :.|.......|.
  Rat   386 SANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVW--DMRGKQFHTGVE 448

  Fly   492 INRWYV--ITPSRNLRE--TQEFVQMCIRTASSMKMNI------C---------NPIYEEIPDDR 537
            |..|.:  ....|..||  .:.|.....:.:....|.|      |         .|::..:
  Rat   449 IKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHL---- 509

  Fly   538 NGTYSQAIDNAAANDPQIVMVVM--RSPNEEKYSCIKKRTCVDRPVPSQVVTLKVIAPRQQKPTG 600
            ..|||..         |:::|::  ::|   .|:.:|:.......:.:|.|.:|.:.  :..|..
  Rat   510 KNTYSGL---------QLIIVILPGKTP---VYAEVKRVGDTLLGMATQCVQVKNVI--KTSPQT 560

  Fly   601 LMSIATKVVIQMNAKLMGAPWQVVIP-------LHGLMTVGFDVCHSP--KNKNKSYGAFVATMD 656
            |.::..|:    |.||.|.. .:::|       ...::.:|.||.|.|  ..|..|..|.|.:||
  Rat   561 LSNLCLKI----NVKLGGIN-NILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMD 620

  Fly   657 QKESFRYFSTVNEHIKGQELSEQMSVNMACALRSYQEQHRSLPERILFFRDGVGDGQLYQVVNSE 721
            ...| ||.:||......||:.:.::..:...|..:.:..|..|.||:|:||||.:||..||:..|
  Rat   621 AHPS-RYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYE 684

  Fly   722 VNTLKDRLDEIYKSAGKQEGCRMTFIIVSKRINSRYF-------TGHRNPVP-GTVVDDVITLPE 778
            :..:::....:.|.  .|.|  :|:|:|.||.::|.|       .|....:| ||.||..||.|.
  Rat   685 LLAIREACISLEKD--YQPG--ITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPY 745

  Fly   779 RYDFFLVSQAVRIGTVSPTSYNVISDNMGLNADKLQMLSYKMTHMYYNYSGTIRVPAVCHYAHKL 843
            .:||:|.|.|...||..|:.|:|:.|:....||:||:|:|::.|.|...:.::.:||..:|||.:
  Rat   746 EFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLV 810

  Fly   844 AF 845
            ||
  Rat   811 AF 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	21/128 (16%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	123/486 (25%)
Ago3	NP_001258122.1	ArgoN	73..167	CDD:465134	15/94 (16%)
		ArgoL1	177..227	CDD:462567	8/49 (16%)
		PAZ_argonaute_like	228..348	CDD:239212	21/128 (16%)
		Piwi_ago-like	393..818	CDD:240015	115/450 (26%)