Protein Alignment aub and Piwil2

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_006252333.2
• Gene: Piwil2 / 306011
• RGDID: 1306964
• Length: 1005
• Species: Rattus norvegicus
• Alignment Length: 892
• Identity: 285/892 - (31%)
• Similarity: 477/892 - (53%)
• Gaps: 64/892 - (7%)

  Fly     2 NLPPNPVIARGRGRGRKPNNVEANRGFAPSLGQ-KSDPSHSEGNQASGGNGGGGD---------A 56
            :||...|:|.|..:     ..||:.|::..||: .||.|.....:|:|..|.|.|         |
  Rat   151 SLPDPSVLAAGDSK-----LAEASVGWSRMLGRGSSDVSLLPLGRAAGSIGRGVDKPPSAFGLTA 210

  Fly    57 QVGPSI-EKSSLSAVQMHKSEGDPRGSVRGRRLITDLVYSRPPGMTSKKGVVGTHITVQANYFKV 120
            :..|.: :..:||...:|.|:..|        ::|  :..:...:..|:|..||..::..|..|:
  Rat   211 RDPPRLPQPPTLSPTSLHSSDPPP--------VLT--IERKEKELLVKQGSKGTPQSLGLNLIKI 265

  Fly   121 LKRPNWTIYQYRVDFTPDVEATRLRRSFLYEHKGILGGY-IFDGTNMFCINQFKAVQDSPYVLEL 184
             :..|..:|||.|.|:|:||...:|...|.:|:.:.|.. .|||:.::.  ..|..|    ::||
  Rat   266 -QCHNEAVYQYHVTFSPNVECKSMRFGMLKDHQSVTGNVTAFDGSILYL--PVKLQQ----LVEL 323

  Fly   185 VTKSRAGE-NIEIKIKAVGSVQSTDAEQFQVLNLILRRAMEGLDLKLVSRYYYDPQAKINLENFR 248
            .::.:..: .|.|||:....::..........|::.||.|:.||:|||.|.:|||.:.:.|:..|
  Rat   324 KSQRKTDDAEISIKIQLTKILEPCSDLCIPFYNVVFRRVMKLLDMKLVGRNFYDPTSAMVLQQHR 388

  Fly   249 MQLWPGYQTSIRQHENDILLCSEICHKVMRTETLYNILSDAI--RDSDDYQSTFKRAVMGMVILT 311
            :|:||||..|||:.:..:.|.:::.|||:|.:::.::: .||  ::.:.:|....:.::|.:::|
  Rat   389 LQIWPGYAASIRRTDGGLFLLADVSHKVIRNDSVLDVM-HAIYQQNKEHFQDECSKLLVGSIVIT 452

  Fly   312 DYNNKTYRIDDVDFQSTPLCKFKTNDG-EISYVDYYKKRYNIIIRDLKQPLVMSRPTDKNIRGGN 375
            .|||:||||||||:..||...|..:|| ||::::||.|.|.|.:::..|||::.||:::....|.
  Rat   453 RYNNRTYRIDDVDWNKTPKDSFVMSDGKEITFLEYYSKNYGITVKEDDQPLLIHRPSERQNNHGT 517

  Fly   376 --DQAIMIIPELARATGMTDAMRADFRTLRAMSEHTRLNPDRRIERLRMFNKRLKSCKQSVETLK 438
              ...|:::|||:..||:.:.|:.|||.::.:::...|:|.:....|....:|:...:.:...|.
  Rat   518 LLKGEILLLPELSFMTGIPEKMKKDFRAMKDLTQQINLSPKQHHSALECLLQRISQNETANNELT 582

  Fly   439 SWNIELDSALVEIPARVLPPEKILFGNQKIFVCDARADWTNEFRTCSMFKNVHINRWYVITPSRN 503
            .|.:.|...:.:|..|:||.|:|...|.. ||.....:|..|....:....:.::.|.:..|.|.
  Rat   583 RWGLSLQKDVHKIEGRLLPMERINLRNTS-FVTSEDLNWVKEVTRDASILTIPMHFWALFYPKRA 646

  Fly   504 LRETQEFVQMCIRTASSMKMNICNPIYEEIPDDRNGTYSQAIDNAAANDPQIVMVV--MRSPNEE 566
            :.:.:|.|.|..:.|..:.|.|..|.:.|:.|||..||.:.|.:....:.:|.|||  :....::
  Rat   647 MDQARELVNMLEKIAGPIGMRISPPAWVELKDDRIETYIRTIQSLLGVEGKIQMVVCIIMGTRDD 711

  Fly   567 KYSCIKKRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATKVVIQMNAKLMGAPWQVVIPLHGLM 631
            .|..|||..||..||||||:.::.|.    :||.|.|:|.|:::|||.||.|..|.|.|||..||
  Rat   712 LYGAIKKLCCVQSPVPSQVINVRTIG----QPTRLRSVAQKILLQMNCKLGGELWGVDIPLKQLM 772

  Fly   632 TVGFDVCHSPKNKNKSYGAFVATMDQKESFRYFSTVNEHIKGQELSEQMSVNMACALRSYQEQHR 696
            .:|.||.|.|....:|...|||:::...: :::|.|...:..||:.:.:.:.:..:|:.|.|.:.
  Rat   773 VIGMDVYHDPSRGMRSVVGFVASINLTLT-KWYSRVVFQMPHQEIVDSLKLCLVGSLKKYYEVNH 836

  Fly   697 SLPERILFFRDGVGDGQLYQVVNSEVNTLK---DRLDEIYKSAGKQEGCRMTFIIVSKRINSRYF 758
            .|||:|:.:||||.||||..|.|.|:..|:   :..|..:.        :|...:|.|:|::..:
  Rat   837 CLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAFDNYHP--------KMVVFVVQKKISTNLY 893

  Fly   759 TGHRN----PVPGTVVDDVITLPERYDFFLVSQAVRIGTVSPTSYNVISDNMGLNADKLQMLSYK 819
            ....:    |.||||||..||..|..||:|::..||.|...||.|..:.:...|:.|.:|.|::|
  Rat   894 LAAPDHFVTPSPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYICVLNTANLSPDHMQRLTFK 958

  Fly   820 MTHMYYNYSGTIRVPAVCHYAHKLAFLVAESINRAPSAGLQNQLYFL 866
            :.|||:|:.|||||||.|.||||||||..:.::..|:..|...|:||
  Rat   959 LCHMYWNWPGTIRVPAPCKYAHKLAFLSGQILHHEPAIQLCENLFFL 1005

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	44/124 (35%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	153/457 (33%)
Piwil2	XP_006252333.2	ArgoL1	371..418	CDD:462567	19/46 (41%)
		PAZ_piwi_like	419..536	CDD:239211	40/117 (34%)
		Piwi_piwi-like_Euk	544..988	CDD:240016	153/457 (33%)