Protein Alignment aub and wago-5

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_495151.3
• Gene: wago-5 / 191545
• WormBaseID: WBGene00022877
• Length: 912
• Species: Caenorhabditis elegans
• Alignment Length: 887
• Identity: 164/887 - (18%)
• Similarity: 322/887 - (36%)
• Gaps: 191/887 - (21%)

  Fly    93 VYSRPPGMTSKKGVVGTHITVQANYFKVLKRPNWTIYQYRVDFTPDVEATRLRRSFLYEHKGILG 157
            :|:.|    ::.|.:|..:.|..|.|.|......|::::.|....|:.:|   :...:..||...
 Worm    39 IYTTP----TEPGTLGKQVDVGTNIFGVEVTKETTVHRFVVHAKADLTST---KEVTFTKKGKED 96

  Fly   158 GYIFDGTNMFCINQFKAVQDSPYVLEL---------------------------VTKSRA----- 190
            ..:.|.....|...|.||:.:|...::                           .|||:.
 Worm    97 FVVLDRREKCCNLFFNAVEKNPDFFKMKDGNHIVYDGQSTLYTTINLFSELDCNQTKSKVFQING 161

  Fly   191 ----------------------GENIEIKIKAVG------SVQSTDAEQFQVLNLILRRAMEGLD 227
                                  ..:|.|..|.:|      :::..:.|..|.|.|.|.:..
 Worm   162 ADTGNDELKTLPCISLEIHAPRDNSITISAKILGERTADQNIEVNNREYTQFLELALNQHC---- 222

  Fly   228 LKLVSRYYYDPQAKINL-----ENFRMQ----------LWPGYQTSI--------RQHENDILLC 269
            .:...|:......|:..     |.|..:          |:||.:.:|        |...|..|:.
 Worm   223 TRETKRFGCFEHGKVYFLNATEEGFDQRDCVDVGDGKALYPGLKKTIQFIEGPFGRGQNNPSLVI 287

  Fly   270 SEICHKVMRTETLYNILSDAI-RDSDDYQSTFKR-----AVMGMVILTDYNNKT--YRIDDVDFQ 326
            ..:.....:.:|:...|.:.. :|..:..|:..|     .:.|:...:.|.::.  .||..:..:
 Worm   288 DGMKAAFHKEQTVIQKLFEITGQDPSNGLSSMAREKATPVIKGLDCYSMYTSRKRHLRIVGIFHE 352

  Fly   327 STPLCKFKTNDGE-ISYVDYYKKRYNIIIRDLKQPLVMSRPTDKNIRGGND---QAIMIIPELAR 387
            |....:|:..||: .|..:|::.:|:|.::..|..||:.:.     ||.|:   ..:|.|.:..|
 Worm   353 SATGTRFELPDGKTCSIAEYFRDKYSINLQYPKANLVVCKD-----RGNNNYFPAELMTISKNQR 412

  Fly   388 AT--GMTDAMRADFRTLRAMSEHTRLNPDRRIERLRMFNKRLKSCKQSVETLKSWNIELDSALVE 450
            ||  ..|.:.:.        ::...:.||.| :|:.:..|...:.....|.|.:..|::.|..::
 Worm   413 ATIPQQTQSQKT--------TKECAVLPDVR-QRIIIKGKTAVNITAENELLNALGIKVYSEPLK 468

  Fly   451 IPARVLPPEKILFGNQKIFVCDARADW---TNEFRTCSMFKNVHINRW--YVITPSRNLR----E 506
            :..:.|       |.|:..|......|   ...|...:.|:::    |  |.: .::|.|    :
 Worm   469 VSLKEL-------GYQRSTVKSELGKWRPPPGSFVKPAAFQDL----WALYAV-GNQNSRFSVSD 521

  Fly   507 TQEFVQMCIRTASSMKMNICNPIYEEIPDDRNGTYSQAIDNAAANDPQIVMVVMR---SPNEEKY 568
            ..:|..|.|.......|.|..|....:....|  ....::||||:..:...|:..   :...:||
 Worm   522 LSQFTGMFIDACKKRGMIIKPPSETSLCHMDN--IISLLENAAASKCKFAFVITDDSITHLHKKY 584

  Fly   569 SCIKKRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATKVVIQMNAKLMGAPWQVVIPLHGL--- 630
            ..:::::.:      .:..:|:.........|.......|:.:.|.||.|..:.|......:
 Worm   585 KALEQKSMM------VIQDMKISKANSVVKDGKRLTLENVINKTNMKLGGLNYTVSDAKKSMTDE 643

  Fly   631 -MTVGFDVCHSP-------KNK---NKSYGAFVATMDQKESFRYFSTVNEHI---KGQELSEQMS 681
             :.:|..|...|       .||   |.....|.:.......|     |.:.:   .||:....:.
 Worm   644 QLIIGVGVSAPPAGTKYMMDNKGHLNPQIIGFASNAVANHEF-----VGDFVLAPSGQDTMASIE 703

  Fly   682 VNMACALRSYQEQHRSLPERILFFRDGVGDGQLYQVVNSEVNTLKDRLDEIYKSAGKQEGCRMTF 746
            ..:..::..::....:||:||:.:|.|..||....::..|:...:..:.      |..:...:.:
 Worm   704 DVLKSSIDLFEMNRNTLPKRIIIYRSGASDGSHASILAYEIPLARATIQ------GYSKDINLIY 762

  Fly   747 IIVSKRINSRYF-----TGHR----NPVPGTVVDDVITLPERYDFFLVSQAVRIGTVSPTSYNVI 802
            |||:|..:.|:|     :|.:    |..||.|:|..:|.|....|||.......||.....|.::
 Worm   763 IIVTKEHSYRFFRDQLRSGGKATEMNIPPGIVLDSAVTNPACKQFFLNGHTTLQGTAKTPLYTIL 827

  Fly   803 SDNMGLNADKLQMLSYKMTHMYYNYSGTIRVPAVCHYAHKLA 844
            :|:.....|:|:.|:|.:.|.:...:.:..:|...:.|::.|
 Worm   828 ADDCNAPMDRLEELTYTLCHHHQIVALSTSIPTPLYVANEYA 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	28/133 (21%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	92/483 (19%)
wago-5	NP_495151.3	PAZ_argonaute_like	297..407	CDD:239212	24/114 (21%)
		Piwi	568..876	CDD:214930	61/319 (19%)