Protein Alignment aub and rde-1

DIOPT Version :9

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_741611.1
• Gene: rde-1 / 179393
• WormBaseID: WBGene00004323
• Length: 1020
• Species: Caenorhabditis elegans
• Alignment Length: 909
• Identity: 178/909 - (19%)
• Similarity: 314/909 - (34%)
• Gaps: 305/909 - (33%)

  Fly   118 FKVLKRPNWTIYQYRVDFTPDVE---ATRLRRSFLYEHKGIL----------------------- 156
            :|.||    .:...:|.:.|.|.   ..:..::|:|::..||
 Worm   186 YKFLK----NVMTQKVRYAPFVNEEIKVQFAKNFVYDNNSILRVPESFHDPNRFEQSLEVAPRIE 246

  Fly   157 ---GGYI-----FDGTNM--FCINQFKAVQDSP------YVLELVTKSRAGENIEIKIKAVGSVQ 205
               |.||     |||..:  |.|.. |...::|      |:|.:|......:::...:|.
 Worm   247 AWFGIYIGIKELFDGEPVLNFAIVD-KLFYNAPKMSLLDYLLLIVDPQSCNDDVRKDLKT----- 305

  Fly   206 STDAEQFQVLNLILRRAMEGLDLKLVSRYYYDPQAKINLENFRM---QLWPGYQTSI-RQHENDI 266
                           :.|.|   |:..|....|:.:..|||.::   ::|....:.: .:|...:
 Worm   306 ---------------KLMAG---KMTIRQAARPRIRQLLENLKLKCAEVWDNEMSRLTERHLTFL 352

  Fly   267 LLCSEICHKVMRTETLYNIL--SDAIRDSDDYQST-FKRAVMGMVILTDYNNKTYRIDDVDFQST 328
            .||.|       ...:|.:.  ||..|::..|.:| ||        :.:.|.|.     ::|...
 Worm   353 DLCEE-------NSLVYKVTGKSDRGRNAKKYDTTLFK--------IYEENKKF-----IEFPHL 397

  Fly   329 PLCKFKTNDGE----ISYVDY------YKKRYNIIIRDLKQPLVMSRPTDKNIRGGNDQAIMIIP 383
            ||.|.|:...|    :.:::.      ||.|.:::::|........:|.|.     .:..:.::.
 Worm   398 PLVKVKSGAKEYAVPMEHLEVHEKPQRYKNRIDLVMQDKFLKRATRKPHDY-----KENTLKMLK 457

  Fly   384 ELARATGMTDAMRADFRTLRAMSEHTRLNPDRRIERLRMFNKRLKSCKQSVETLKSWNIELDSAL 448
            ||            ||.:                |.|. |.:|...|.:             ..:
 Worm   458 EL------------DFSS----------------EELN-FVERFGLCSK-------------LQM 480

  Fly   449 VEIPARVLP-----------------------------PEKIL----------FGNQKIFVCDAR 474
            :|.|.:||.                             |||.|          .||..:...|..
 Worm   481 IECPGKVLKEPMLVNSVNEQIKMTPVIRGFQEKQLNVVPEKELCCAVFVVNETAGNPCLEENDVV 545

  Fly   475 ADWTNEFRTCSMFKNVHI----NR-----WYVITPSRNLRETQEFVQMCIRTASSMKMNI----C 526
            ..:|.....|. |:.:.|    ||     .|..|     :....|.:.|.......:..|    .
 Worm   546 KFYTELIGGCK-FRGIRIGANENRGAQSIMYDAT-----KNEYAFYKNCTLNTGIGRFEIAATEA 604

  Fly   527 NPIYEEIPDDRNGTYSQAIDNAAANDPQIVMVVMRSPNE------EKYSCIKKRTCVDRPVPSQV 585
            ..::|.:||               .:.:::|.::.|..:      .|:.|.......::.:.|:.
 Worm   605 KNMFERLPD---------------KEQKVLMFIIISKRQLNAYGFVKHYCDHTIGVANQHITSET 654

  Fly   586 VTLKVIAPRQQKPTGLMSIATKVVIQMNAKLMG----APWQVV-------------IPLHGLMTV 633
            ||..:.:.|.:|  |...|..::.:::||||.|    ..|..:             :||  .|.|
 Worm   655 VTKALASLRHEK--GSKRIFYQIALKINAKLGGINQELDWSEIAEISPEEKERRKTMPL--TMYV 715

  Fly   634 GFDVCH--SPKNKNKSYGAFVATMDQKES-FRYFSTVNEHIK--------GQELSEQMSVNMACA 687
            |.||.|  |....:.|..|.||:::...: :|......|..:        |:|.::.:.......
 Worm   716 GIDVTHPTSYSGIDYSIAAVVASINPGGTIYRNMIVTQEECRPGERAVAHGRERTDILEAKFVKL 780

  Fly   688 LRSYQEQH-RSLPERILFFRDGVGDGQLYQVVNSEVNTLKDRLDEIYKSA-GKQEGCRMTFIIVS 750
            ||.:.|.: ...|..|:.:||||.|.::.:|.:.|:.:||..:.:..... |:....:.|||::.
 Worm   781 LREFAENNDNRAPAHIVVYRDGVSDSEMLRVSHDELRSLKSEVKQFMSERDGEDPEPKYTFIVIQ 845

  Fly   751 KRINSRYF--------------------------------------TGHRNPVPGTVVDDVITLP 777
            ||.|:|..                                      ||..||..||.||.:|...
 Worm   846 KRHNTRLLRRMEKDKPVVNKDLTPAETDVAVAAVKQWEEDMKESKETGIVNPSSGTTVDKLIVSK 910

  Fly   778 ERYDFFLVSQAVRIGTVSPTSYNVISDNMGLNADKLQMLSYKMTHMYYNYSGTIRVPAVCHYAH 841
            .::||||.|....:||..|..|.|:.|:.|::.|::..::|.:..:.......|.:|...||||
 Worm   911 YKFDFFLASHHGVLGTSRPGHYTVMYDDKGMSQDEVYKMTYGLAFLSARCRKPISLPVPVHYAH 974

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	ArgoN	105..219	CDD:293095	24/142 (17%)
		PAZ_piwi_like	272..392	CDD:239211	24/132 (18%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	115/568 (20%)
rde-1	NP_741611.1	PAZ_argonaute_like	280..419	CDD:239212	33/181 (18%)
		Piwi_ago-like	467..982	CDD:240015	113/547 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870