Protein Alignment aub and sago-1

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_504610.1
• Gene: sago-1 / 179016
• WormBaseID: WBGene00019666
• Length: 881
• Species: Caenorhabditis elegans
• Alignment Length: 930
• Identity: 174/930 - (18%)
• Similarity: 307/930 - (33%)
• Gaps: 332/930 - (35%)

  Fly   108 GTHITVQANYFKVLKRPNWTIYQYRVDFTPDVEATRLRRSFLYEHKGILGGYIFDGTNMFCINQF 172
            ||.:.:..|..|:....|.:|::|.|...           |:|:..        |||.:
 Worm    41 GTPVQIVTNMRKINLEKNHSIFKYSVQVL-----------FVYQKS--------DGTEL------ 80

  Fly   173 KAVQDSPYVLELVTKSRAGENIEIKIKAVGSVQSTDAEQFQVLNLILRRAMEGLDLKLVSRYYYD 237
                    |||             |.|:|||....:..:...|.:..:.|.:..:||....:.||
 Worm    81 --------VLE-------------KSKSVGSGCDHERSKSHCLRVYRKAAKQCQELKSGGPFCYD 124

  Fly   238 PQ------AKINLENFRMQLW-------PGY----------QTSIRQHENDILLCSEICHKVMRT 279
            .|      :|:..:.|...:.       |.:          |.|.:...||:.. |..|...::.
 Worm   125 SQGCLYSFSKLKNDEFSTNITGSDISNNPKFLRVEFKLAKVQESFQTTTNDVAK-SVNCRPALQE 188

  Fly   280 ETLY---------------NIL--------------------------------SDAIRDSD--- 294
            :|:.               |:|                                |.::|..:
 Worm   189 KTILEAMNQIVSTAPINHPNVLTIGNCVHYLYDDTNIDIRSITGEGGKSSAVGASKSVRTLEGTG 253

  Fly   295 ----------------------------DYQ---------STF----KRAVMGMVILT------D 312
                                        ||:         |.|    |.|.:|:...|      |
 Worm   254 KTPCLYMATELKTTLFHPDNCSLLKVFMDYRGFNGSLKANSPFVLKNKNAFIGLWCYTTHGKCSD 318

  Fly   313 YNNKTYRIDDVDF-QSTPLCKFKTNDGEISYVDYYKKRYNIIIRDLKQP---LVMSRPTDKNIRG 373
            :.:....|...|| .|.....|:.::.:||..:|::.:||:   .||.|   .|::|..|
 Worm   319 WKDDRPMIKIKDFGLSAKETTFERDNKKISVFNYFQVKYNM---TLKYPDLFTVVARGKD----- 375

  Fly   374 GNDQAI------MIIPELARATGMTDAMRADFRTLRAMSEHTRLNPDRRIERLRMFNKRLKSCKQ 432
            |.:|.|      :...:..|...|....:||...|.|...|.|                    |:
 Worm   376 GKNQHIPVECLDLCNSQTVRTEQMVGTEQADLIKLAAAKPHDR--------------------KK 420

  Fly   433 SVETLKSWNIELDS---------ALVEIPARVLPPEKILF-GNQKIFVCD--ARADWTNEFRTCS 485
            ..:|:.: :|.|.|         |...:...|||...|.| |.:|:|..|  .|...|:.....:
 Worm   421 ITDTVVN-SIGLASEPKGIISVGAPESVTGLVLPKPDIYFSGGKKVFWNDPKKRGPATDFMPAGT 484

  Fly   486 MFKNVHINRWYVITPSRNLRETQEFVQMCIRTASSMKMNICNPIYEEIPDDRNGTYSQAI-DNAA 549
            ..|...:..|.|:..  |..:..:.:|....|...:.|.:.||....|    |..|.::| :||.
 Worm   485 FIKPTKLTNWEVVFD--NGVQLVDCIQHLTSTMRQLGMEVSNPTVSLI----NRGYLRSIFENAK 543

  Fly   550 ANDPQIVMVVMRSPN--EEKYSCIKKRTCVDRPVPSQVVTLK-VIAPRQQKPTGLMSIATKVVIQ 611
            |.:.|::|.:.:|.|  ..:..|:::    :..:.:|.:..: .:...||:.|     ...::.:
 Worm   544 AANRQLIMFITKSMNNYHTEIKCLEQ----EFDLLTQDIRFETAVKLAQQQNT-----RKNIIYK 599

  Fly   612 MNAKLMGAPWQV---VIPLHGLMTVGFD--------------------VCHSP---------KNK 644
            .|.||.|..:::   |......:.:||:                    :.||.         |..
 Worm   600 TNMKLGGLNYELRSGVFSNSKRLIIGFETSQRGGLGDAPIAIGFAANMMSHSQQFAGGYMFVKKS 664

  Fly   645 NKSYGAFVATMDQKESFRYFSTVNEHIKGQELSEQMSVNMACALRSYQEQHRSLPERILFFRDGV 709
            ..:||..:..:        ..|:.:..|....:::                   |:.:|.:..||
 Worm   665 ADNYGPVIPEI--------LLTILKQAKANRPNDR-------------------PDELLIYFSGV 702

  Fly   710 GDGQLYQVVN----SEVNTLKDRLDEIYKSAGKQEGCRMTFIIVSKRINSRYFT-----GHRNPV 765
            .:|| :.:||    ::|.......:|.::.       .:|.|:.||..|:|.:.     |..|..
 Worm   703 SEGQ-HALVNEYYANQVKAACGLFNESFRP-------HITLILASKVHNTRVYKSENGGGVCNVE 759

  Fly   766 PGTVVDDVITLPERYDFFLVSQAVRIGTVSPTSYNVISDNMGLNADKLQMLS----------YKM 820
            ||||:|..|..|...:::......|.||.....|::|     .|..|.:.||          |:|
 Worm   760 PGTVIDHTIVSPVLSEWYHAGSLARQGTSKLVKYSLI-----FNTKKNEKLSVYERLTNELCYEM 819

  Fly   821 THMYYNYSGTIRVPAVCHYA 840
            ..:::..|    :|...|.|
 Worm   820 QIVFHPTS----LPIPLHIA 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	35/226 (15%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	100/508 (20%)
sago-1	NP_504610.1	PAZ	281..412	CDD:198017	33/138 (24%)
		Piwi-like	443..844	CDD:239208	91/452 (20%)