Protein Alignment aub and wago-10

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_503177.1
• Gene: wago-10 / 178560
• WormBaseID: WBGene00020707
• Length: 990
• Species: Caenorhabditis elegans
• Alignment Length: 829
• Identity: 185/829 - (22%)
• Similarity: 321/829 - (38%)
• Gaps: 215/829 - (25%)

  Fly   100 MTSKKGVVGTHITVQANYFKVLK-RPNWTIY---------QYRVDFTPDVE---ATRLRRSFLYE 151
            :|||       ::.:.:|..|:| ||:..||         ..|::.|..||   :.:|..|
 Worm   178 ITSK-------LSRKKDYTYVMKIRPSGFIYTSGEEASEVANRMELTRCVEIVTSQKLNNS---- 231

  Fly   152 HKGILGGYIFDGTNMFCINQFKA--VQDSPYVLEL---------VTKSRAGEN---IEIKIKAVG 202
                  .|...|.:.|   .|:|  |.:.....|:         :.:.|.|:|   :.|..||..
 Worm   232 ------DYCQFGNDTF---SFRAQPVSEPDATSEIRSGFAKVSRIVEGRNGKNEMLMAIDTKASP 287

  Fly   203 SVQSTDAEQFQVLNLILRRAMEGLDLKLVSRYYYDPQAKINLENFRMQLWPGYQTSIRQHENDIL 267
            ..:||     .|||.:..:.:|   .:..||..|..:...|.:.     ..|..|....|::
 Worm   288 FYKST-----SVLNFVCGKYLE---KRGSSRNDYRGRGDYNRKK-----TGGGSTDAPDHQD--- 336

  Fly   268 LCSEICHKVMRTETLYNILSDAIRDSDDYQSTFKRAVMGMVILTDY-NNKT-----YRIDDVDFQ 326
             .:|:...:...|....|               :.|:.|:::...: .|.|     .|:.:.:.:
 Worm   337 -VAEVERSLEYRENRQQI---------------EEALKGLLVSAAHLKNSTNLIMISRVAETNSE 385

  Fly   327 STPLCKFKTNDG--EISYVDYYKKRYNIIIRDLKQPLVMSRPTDKNIRGGNDQAIMIIPELARAT 389
            :|   ||.||:|  |||..|:|.:.||..::..|.|||:|    |..|   |:....:..|..|.
 Worm   386 TT---KFMTNNGEREISVADHYLEAYNYRLKYPKMPLVVS----KRFR---DECFYPMELLQVAP 440

  Fly   390 G-------MTDAMRADFRTLRAMSEHTRLNPDRRIERLR-MFNKRLKSCKQSVETLKSWNIELDS 446
            |       |:.|::      .||.......|.:.::.:: :.::.||..:...  :.::.|:|:|
 Worm   441 GQRIKDHKMSAAVQ------MAMKGQKSTLPQKHVDLVKHVLSRNLKLDRNLY--MDAFGIKLES 497

  Fly   447 A-LVEIPARVLPPEKILF---------GNQKIFVCDARADWTNEFRTCSMFKN-VHINRWYVITP 500
            | ||::.:::|||.:|.|         ||.             .|||...|.: ..||...::..
 Worm   498 AELVKLQSKILPPPQIKFKDEVYMPKMGNP-------------VFRTNGRFVDPADINAVAIVVF 549

  Fly   501 SR--NLRETQEFVQ----MCIRTASSMKMNICN-PIYEEIPDDRNGTYSQAIDNAA----ANDPQ 554
            .|  ::|:.:.|..    .|.....::|.:..: ||.|...:|     |.||.||.    :....
 Worm   550 DRAIDMRQAENFCDRLSCYCRENGITVKKSSRDWPIREINSED-----SVAIKNAMEKWFSKGVN 609

  Fly   555 IVMVVMRSPNEEKYSCIKKRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATKVVIQMNAKLMGA 619
            |::.:.:....:.:..:|   ..:..|..|.:.:..........:|....|..|:.:.|.|..|.
 Worm   610 ILVAIAKEKKPDVHDVLK---YYEASVGLQTIQVCKQTVDMMLSSGGRQTADNVMRKFNLKCGGT 671

  Fly   620 PWQVVIP--LHG-----------------LMTVGFDVCHSPKNK--NKSYGAFVATMDQKES--- 660
            .:.|.||  ::|                 :..:|||:.|.....  ::|.|    .||.:.|
 Worm   672 NFFVQIPRSVNGRTVCADAHLLNEKLFERVQFIGFDISHGASRTLFDRSTG----KMDGEVSIVG 732

  Fly   661 -------------FRYFSTVNEHIKGQELSEQMSVNMACALRSYQEQHRSLPERILFFRDGVGDG 712
                         |.|..|..|: |.|:|.|   |...| :.||:.....||.:|:.:|.|.|:|
 Worm   733 VSYSLSHSTHLGGFAYMQTQKEY-KLQKLDE---VFPKC-VDSYRNHTGRLPSKIVIYRIGAGEG 792

  Fly   713 QLYQVVNSEVNTLKDRLDEIYKSAGKQEGCRMTFIIVSKRINSRYFTGH--------RNPVPGTV 769
            . ::.|..||:.::...:.|......|    :..||..:..:.|.|..|        :|...||.
 Worm   793 D-FKRVKEEVDKIRGTFNRIQPDYRPQ----LVVIIAQRDSHVRVFPAHITGSKAGQQNVTSGTC 852

  Fly   770 VDDVITLPERYDFFLVSQAVRIGTVSPTSYNVISDNMGLNADKLQMLSY 818
            ||.|||.....:|.|.||...:|||.|..|.:::::......::..|:|
 Worm   853 VDSVITSLGHQEFILSSQMPLLGTVRPCKYTILTNDPNWTKTEITHLTY 901

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	31/134 (23%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	109/487 (22%)
wago-10	NP_503177.1	PAZ_argonaute_like	347..439	CDD:239212	29/116 (25%)
		ArgoL2	<478..515	CDD:465136	12/38 (32%)
		Piwi-like	499..932	CDD:239208	100/438 (23%)