Protein Alignment aub and csr-1

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001040938.1
• Gene: csr-1 / 177591
• WormBaseID: WBGene00017641
• Length: 1030
• Species: Caenorhabditis elegans
• Alignment Length: 1087
• Identity: 209/1087 - (19%)
• Similarity: 357/1087 - (32%)
• Gaps: 373/1087 - (34%)

  Fly    12 GRGRGR-------KPN------------NVEANRGFAPSLGQKSDP------SHSEGNQASGGN- 50
            ||||||       :|:            .|:...|.......:..|      ||.:|.:.|.||
 Worm    21 GRGRGRGGYGDSYRPDLETRETHVTYQGKVKYEGGDRHDFNYEKTPTGSYRGSHRDGQEGSRGNR 85

  Fly    51 ----GGGGDAQVGPSIEKSSLSAVQMHKSEGDPRGSVRGRRLITDLVYSRPPGMTSKKGVVGTHI 111
                ||.|........|:|.........:.|...|:.|||           .|.:.:.|...| .
 Worm    86 GSFRGGRGGYDRRRDDEESKAENRFGGYNRGANGGNYRGR-----------TGGSGRGGSTQT-T 138

  Fly   112 TVQANYFKVLKRPNWTIYQYRVD-----FTPDVEATRLRRSFLYEHKGILGGYIFDGTNMFCINQ 171
            ||...|       |..|.:...:     ...|:...:..|..|    .|.|..:.:.|....:.|
 Worm   139 TVDPKY-------NGLILENSAEPKLKGLNSDMNQKQNPRLAL----NIFGLELSERTIFRHVVQ 192

  Fly   172 FKAV---QDSPYVLELVTKSRAGENIEIKIKAVGSVQSTDAEQFQVLNLILRR------------ 221
            .|.:   .:..|:  |.|.|..|.         |:..:...:.|.:|:::|::
 Worm   193 MKLIDRQHNKEYI--LTTMSARGR---------GNRATKQKDNFILLDILLKQWAAKKGQQNLPA 246

  Fly   222 ----------AMEGLDLKLVSRYYYDPQAKINLENFRMQLWPGYQTSIRQHENDI-LLCSEICHK 275
                      .:||:.| :|.....|......|.||       .:.||.....|: :.|.....|
 Worm   247 FAYDGAQSLFTLEGISL-MVDIKKEDALEIPELSNF-------LKDSISFLSGDLEISCEPDLEK 303

  Fly   276 VMRTETLYNILSD--------------AIRDSDDYQSTFKRAVMGMVILTDY------------- 313
            ....:|..|..||              ||| |:.|.|..|    |:.:.|..
 Worm   304 PSFVQTELNEWSDPRFYAYLDIVTSQSAIR-SERYLSQSK----GLYVHTQSLEELRVKWAVAAK 363

  Fly   314 ----------NNKTYRIDDVDFQST------PLCKFKTNDGEISYV---DY-----------YKK 348
                      .|....|.::|.|||      ||.:.      :.|.   |:           .::
 Worm   364 GIHKGCRIVGANGPLPILELDPQSTQYYASIPLSQM------LQYAFPRDFPPNRIVNPNMKLQR 422

  Fly   349 RYNIIIRDLKQPLVMSRP--TDKNIRGGNDQAIMII-------PELARATGMTDAMRADFRTLR- 403
            ...::::|||     ..|  .||.|...|...:..:       ||          .|..:..|:
 Worm   423 AVKLLLKDLK-----CNPYYDDKQIWATNTITVSDVDYNAPKDPE----------FRQKYPNLKF 472

  Fly   404 --------AMSEHTRLNP------------DRRI--------------ERLRMFNKRLKSCKQSV 434
                    ....|.||.|            |||:              ||.....|.......:.
 Worm   473 PMLPAVQCGTGPHKRLMPLEYLKVLPYQSIDRRVLEEFELTPRANAPNERWSTLQKHYDQFGFND 537

  Fly   435 ETLKSWNIEL----DSALVEIPA-RVLPPEKILFGNQKIFVCDARADW---TNEFRTCS-----M 486
            :.:|.:.:::    .:.:.||.. |||.| .:.:.: .:.|.|.:.||   ..:|.|.:     |
 Worm   538 QVMKDFGVQICNDPFNNVSEIDGERVLAP-SVAYAD-PVHVDDEKRDWKAQDKKFVTPATIDHLM 600

  Fly   487 F------------------------------KNVHINRWYVITPSRNLRETQEFVQMCIRTASSM 521
            |                              |.:||.. |.:......|.::.|:      .|..
 Worm   601 FVLVAGYTRTWDADCDATKFVAKAFMQRCKDKGMHIGS-YSMDQHNGERGSENFL------TSVF 658

  Fly   522 KMNICNPIYEEIPDDRNGTYSQAIDNAAANDPQIVMVVMRSPNEEKYSCIKKRTCVDRPVPSQVV 586
            |..:.:|.|      |:.:::          |.::.:....||  .:.|:|....:. .:|:|.|
 Worm   659 KNLVTHPNY------RDSSFT----------PFVLFISDDVPN--IHECLKFEERMS-DIPTQHV 704

  Fly   587 TLKVIAPR----QQKPTG----LMSIATKVVIQMNAKLMGAPWQVVIPLH-------GLMTVGFD 636
            .||.:...    ::|..|    .......:|::.|.|..|..:...||..       ....:|.|
 Worm   705 LLKNVKKMRDNIEKKSQGGRRAYDLTLDNIVMKANIKCGGLNYTADIPRDLACWNEVSTFVIGMD 769

  Fly   637 V-------------------CHSPKNKNKSYGAFVATMDQKESFRYFSTVNEHIKGQELSEQMSV 682
            |                   |:|.:|.....|.|:.|..::|:      :.:.|. ::.::|...
 Worm   770 VAHPDRNAAREGNPSTVGLSCNSAENPYSFIGDFLYTDPRREA------IQDEIL-RKFTDQSVR 827

  Fly   683 NMACALRSYQEQHRSLPERILFFRDGVGDGQLYQVVNSEVNTLK--DRLDEIYKSAGKQEG---- 741
            |.|        :.|..|::::.|||||..|:       |...||  :.:::..|:|.|..|
 Worm   828 NFA--------EIRGFPKKVIIFRDGVSFGE-------ETAALKEVEIIEQTIKTAAKSMGHSDY 877

  Fly   742 -CRMTFIIVSKRINSRYFT--GHR-----NPVPGTVV-DDVITLPERYDFFLVSQAVRIGTVSPT 797
             .::..|:|.||.::|::.  ||.     ||:|.|.| .|:....:|..|....:.|: ||....
 Worm   878 APKVLAIVVKKRHHTRFYAKGGHHGNMPINPLPDTSVGGDIAEYGKRQIFIQAFRPVQ-GTAKVP 941

  Fly   798 SYNVISDNMGLNADKLQMLSYKMTHMYYNYSGTIRVPAVCHYAHKLA 844
            |:.||.|:..::.:.:..:...:..::...:....:|...:.||:||
 Worm   942 SFLVIRDDEEVSDEHVAKMVCAVCSLHQLVNSPTSIPTPVYVAHELA 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	34/185 (18%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	111/572 (19%)
csr-1	NP_001040938.1	PAZ_argonaute_like	361..497	CDD:239212	26/156 (17%)
		Piwi-like	555..993	CDD:239208	99/485 (20%)