Protein Alignment aub and alg-4

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_499191.1
• Gene: alg-4 / 176400
• WormBaseID: WBGene00006449
• Length: 1040
• Species: Caenorhabditis elegans
• Alignment Length: 1024
• Identity: 223/1024 - (21%)
• Similarity: 391/1024 - (38%)
• Gaps: 276/1024 - (26%)

  Fly    20 NNVEANRGFAPSLGQKSDPSHSEGNQASGGNGGGGDAQVGPSIEKSSLSAVQMHKSEGDPRGSVR 84
            ||...:.|.:.| |..|.|..|  ..|||        |..|.....|||..|....:|....::.
 Worm    12 NNTLTSSGISGS-GSMSPPITS--RPASG--------QASPLTSNGSLSPPQYADDQGSVSYNLD 65

  Fly    85 GRRLITDLVYSR-----------PPGMTSKKGVVGTHITVQANYFKV-LKRPNWTIYQYRVDFTP 137
            ..|.::.|:.|.           .||:    |.:|..|.|::|:|.: ||.|...:.||.|
 Worm    66 SPRDLSPLLLSELACLNMREVVARPGL----GTIGRQIPVKSNFFAMDLKNPKMVVIQYHV---- 122

  Fly   138 DVEATRLRRSFLYEHKGILGGYIFDGTNMFCINQFKAVQDSPYVLELVTK--------------- 187
            ::.....|:....|.:.|....:.|..|:| .|:|....|..:.|..|.:
 Worm   123 EIHHPGCRKLDKDEMRIIFWKAVSDHPNIF-HNKFALAYDGAHQLYTVARLEFPDDQGSVRLDCE 186

  Fly   188 ------SRAGENIEIKIKAVGSV----QSTDAEQ--------FQVLNLILRRAMEGLDLKLVSRY 234
                  :|......|.|:.||.|    |.|....        .|:|::|.|:::....||..:.:
 Worm   187 ASLPKDNRDRTRCAISIQNVGPVLLEMQRTRTNNLDERVLTPIQILDIICRQSLTCPLLKNSANF 251

  Fly   235 Y------YD-PQA---KINLENFRMQLWPGYQTSIRQHEN-DILLCSEICH------KVMRTETL 282
            |      |. |.|   .::||..: ::|.|:.:|.....| ..||..::.|      ::...:.:
 Worm   252 YTWKSSCYRIPTAAGQALDLEGGK-EMWTGFFSSAHIASNYRPLLNIDVAHTAFYKTRITVLQFM 315

  Fly   283 YNILSDA---------------------------------------------IRDS--------- 293
            .::|::.                                             :||.
 Worm   316 CDVLNERTSKPNRNNPRGPGGPGGPGGYRGGRGGGRGGSYGNFGNRGPPGANVRDDFGGNGLTFT 380

  Fly   294 ------DDYQSTFKR-----AVMGMVILTDYNNKTYRIDDVDFQSTPLCK--FKTNDGE-----I 340
                  |...|:|:.     |:.||.|...:.....|:..|:....|..|  |:..|.|     .
 Worm   381 MDTLSRDTQLSSFETRIFGDAIRGMKIRAAHRPNAIRVYKVNSLQLPADKLMFQGIDEEGRQVVC 445

  Fly   341 SYVDYYKKRYNIIIRDLKQPLVMSRPTDKNIRGGNDQAIMIIPE-------------LARATGMT 392
            |..||:.::|. .::..|.|.:...|..:||....:..::..|:             :.:|..:.
 Worm   446 SVADYFSEKYG-PLKYPKLPCLHVGPPTRNIFLPMEHCLIDSPQKYNKKMSEKQTSAIIKAAAVD 509

  Fly   393 DAMRADFRTLRAMSEHTRLNPDRRIERLRMFNKRLKSCKQSVET---LKSWNIELDSALVEIPAR 454
            ...|.|                 ||::|        :.:.|..|   ||.:.:.:.|.:::..||
 Worm   510 ATQRED-----------------RIKQL--------AAQASFGTDPFLKEFGVAVSSQMIQTTAR 549

  Fly   455 VLPPEKILFG------NQKIFVCDARADWTNEFRTCSMFKNVHINRWYVITPSRNLRETQEFVQM 513
            |:.|..|:||      |..:|..|  ..||.:.:|..|...........:...|:....|.|.|.
 Worm   550 VIQPPPIMFGGNNRSVNPVVFPKD--GSWTMDNQTLYMPATCRSYSMIALVDPRDQTSLQTFCQS 612

  Fly   514 CIRTASSMKMN----------------ICNPIYEEIPDDRNGTYSQAIDNAAANDPQIVMVVMRS 562
            ....|::|.||                :|. ::.||.|:      ..:.|...:   .::||::|
 Worm   613 LTMKATAMGMNFPRWPDLVKYGRSKEDVCT-LFTEIADE------YRVTNTVCD---CIIVVLQS 667

  Fly   563 PNEEKYSCIKKRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATKVVIQMNAKLMGAPWQVV--- 624
            .|.:.|..:|:::.:...:.||.|.:|.::    :||  .:....:|:::|.|:.|...::|
 Worm   668 KNSDIYMTVKEQSDIVHGIMSQCVLMKNVS----RPT--PATCANIVLKLNMKMGGINSRIVADK 726

  Fly   625 -----IPLHGLMTVGFDVCHSPKNKNK----SYGAFVATMD-QKESFRYFSTVNEHIKGQELSEQ 679
                 :.....|.||.||.|..:.:.:    |..|.||.:| ..:|:      ..::|.|:...:
 Worm   727 ITNKYLVDQPTMVVGIDVTHPTQAEMRMNMPSVAAIVANVDLLPQSY------GANVKVQKKCRE 785

  Fly   680 MSVNMACALR----SYQEQHRSLPERILFFRDGVGDGQLYQVVNSEVNTLKDRLDEIYKSAGKQE 740
            ..|.:..|:|    ::....:..|.||:.:||||.:||..:|:..|:.:::.....|      .|
 Worm   786 SVVYLLDAIRERIITFYRHTKQKPARIIVYRDGVSEGQFSEVLREEIQSIRTACLAI------AE 844

  Fly   741 GCR--MTFIIVSKRINSRYFTGHRNPV--------PGTVVDDVITLPERYDFFLVSQAVRIGTVS 795
            ..|  :|:|:|.||.::|.|..::|.:        |||.||..|..||.:||:|.|.....||..
 Worm   845 DFRPPITYIVVQKRHHARIFCKYQNDMVGKAKNVPPGTTVDTGIVSPEGFDFYLCSHYGVQGTSR 909

  Fly   796 PTSYNVISDNMGLNADKLQMLSYKMTHMYYNYSGTIRVPAVCHYAHKLA 844
            |..|:|:.|.....||::|.::|.|.|.|...:.::.:|...:||..:|
 Worm   910 PARYHVLLDECKFTADEIQSITYGMCHTYGRCTRSVSIPTPVYYADLVA 958

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	29/210 (14%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	120/497 (24%)
alg-4	NP_499191.1	ArgoN	154..235	CDD:465134	15/80 (19%)
		ArgoL1	262..306	CDD:462567	11/44 (25%)
		PAZ_argonaute_like	374..484	CDD:239212	23/110 (21%)
		Piwi_ago-like	530..964	CDD:240015	115/459 (25%)