Protein Alignment aub and alg-2

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_871992.1
• Gene: alg-2 / 173468
• WormBaseID: WBGene00000106
• Length: 910
• Species: Caenorhabditis elegans
• Alignment Length: 943
• Identity: 212/943 - (22%)
• Similarity: 366/943 - (38%)
• Gaps: 219/943 - (23%)

  Fly    30 PSLGQKS------DPSHSEGNQASGGNGGGGDAQVGPSIEKSSLSAVQMHKSEGDPRGSVRGRRL 88
            |.||:.|      |...|......||......:|:|                 |...|:: |.:.
 Worm    10 PRLGKLSIFEMPGDSLTSSSFMPDGGAETSSSSQLG-----------------GSAHGAI-GTKP 56

  Fly    89 ITDLVYSRPPGMTSKKGVVGTHITVQANYFKVLKRPNWTIYQYRVDFTPDVEATRLRRSFLYEHK 153
            ...:.:..|  :....||.|..|.::||:|.| :.|..::..|::|..||....|:.|..:
 Worm    57 DAGVQFQCP--VRPNHGVEGRSILLRANHFAV-RIPGGSVQHYQIDVFPDKCPRRVNREVI---- 114

  Fly   154 GIL----GGY------IFDGTNMFCINQFKAVQDSP--YVLELVTKSRAGENIEIKIKAVGS--- 203
            |.|    ..|      ::||.......:...:...|  :.:.|...|.......:.:|.:|.
 Worm   115 GCLISSFSKYFTNIRPVYDGKRNMYTREPLPIGTEPMNFEVTLPGDSAVERKFSVTMKWIGQVCL 179

  Fly   204 ----------VQSTDAEQFQVLNLILRRAMEGLDLKLVSRYYYDPQA--KINLENFR-------M 249
                      |:....|..|.:::|||. :..|....|.|.::.|..  |..::..:       .
 Worm   180 SALDDAMEGRVRQVPHEAVQSIDVILRH-LPSLKYTPVGRSFFTPPGVMKPGMQMHQESKLGGGR 243

  Fly   250 QLWPGYQTSIRQHENDILLCSEIC----HKVMRT--------ETLYNILSDAIRDSDDYQSTFKR 302
            ::|.|:..|:|..:..::|..::.    ::.|..        |.....|::....||..:..|.:
 Worm   244 EVWFGFHQSVRPSQWKMMLNIDVSATAFYRAMPVIEFVAEVLELPVQALAERRALSDAQRVKFTK 308

  Fly   303 AVMGMVI-LTDYN--NKTYRIDDV-----DFQSTPLCKFKTNDG-EISYVDYYKKRYNIIIRDLK 358
            .:.|:.| :|...  .:.||:.:|     ..|:.|| :.:|... |.:...|:..:|.|   .||
 Worm   309 EIRGLKIEITHCGAVRRKYRVCNVTRRPAQTQTFPL-QLETGQTIECTVAKYFFDKYRI---QLK 369

  Fly   359 QPLVMSRPTDKNIRGGNDQAIMIIPELARATGMTDAMR-----ADFRTLRAMSEHTRLNPDRRIE 418
            .|.:..      ::.|.:|....:|  .....:....|     .|.:|...:....|..|:|..|
 Worm   370 YPHLPC------LQVGQEQKHTYLP--PEVCDIVPGQRCLKKLTDVQTSTMIKATARSAPERERE 426

  Fly   419 RLRMFNKRLKSCKQSVETLKSWNIELDSALVEIPARVLPPEKILFG----------NQKIFVCDA 473
            ..::.:|...|......   .:.|.::.|:.|:..|||...|:|:|          ||.::  |.
 Worm   427 ICKLVSKAELSADPFAH---EFGITINPAMTEVKGRVLSAPKLLYGGRHRATTALPNQGVW--DM 486

  Fly   474 RADWTNEFRTCSMFKNVHINRWYVITPSRNLRETQEFVQMCIRTASSMKMNICNPIYEEIPDDRN 538
            |.   .:|.|     .:.:..|.:               .|....|.:|.|.......::
 Worm   487 RG---KQFHT-----GMEVRTWAI---------------ACFAQQSHVKENDLRMFTTQL----- 523

  Fly   539 GTYSQAIDNAAANDPQIVMVVMRSPNEEKYSCIKKRTCVDRPVP---------SQVVTLKVIAP- 593
                |.|...|.      |.::.:|...||:     :.|::..|         |.:..:.|:.|
 Worm   524 ----QRISTDAG------MPIIGTPMFCKYA-----SGVEQVEPMFKYLKQTYSAIQLIVVVLPG 573

  Fly   594 -----RQQKPTG--LMSIATKVV-----------------IQMNAKLMGAPWQVVIP-------L 627
                 .:.|..|  ::.|||:.|                 ::||.||.|.. .:::|       .
 Worm   574 KTPIYAEVKRVGDTVLGIATQCVQAKNAIRTTPQTLSNLCLKMNVKLGGVN-SILLPNVRPRIFN 637

  Fly   628 HGLMTVGFDVCH--SPKNKNKSYGAFVATMDQKESFRYFSTVNEHIKGQELSEQMSVNMACALRS 690
            ..::.:|.|:.|  :...:..|..|.|.:||...| ||.:||......||:...::..:...|..
 Worm   638 EPVIFLGCDITHPAAGDTRKPSIAAVVGSMDAHPS-RYAATVRVQQHRQEIITDLTYMVRELLVQ 701

  Fly   691 YQEQHRSLPERILFFRDGVGDGQLYQVVNSEVNTLKDRLDEIYKSAGKQEGCRMTFIIVSKRINS 755
            :....|..|.||:.:||||.:|||:.|:..|:..:::..  :...:|.|.|  :|||.|.||.::
 Worm   702 FYRNTRFKPARIVVYRDGVSEGQLFNVLQYELRAIREAC--VMLESGYQPG--ITFIAVQKRHHT 762

  Fly   756 RYFTGHR--------NPVPGTVVDDVITLPERYDFFLVSQAVRIGTVSPTSYNVISDNMGLNADK 812
            |.|...:        |..|||.||..||.|..:||||.|.|...||..|:.|:|:.|:..|.||:
 Worm   763 RLFAADKADQVGKAFNIPPGTTVDVGITHPTEFDFFLCSHAGIQGTSRPSHYHVLWDDNDLTADE 827

  Fly   813 LQMLSYKMTHMYYNYSGTIRVPAVCHYAHKLAF 845
            ||.|:|:|.|.|...:.::.:||..:|||.:||
 Worm   828 LQQLTYQMCHTYVRCTRSVSIPAPAYYAHLVAF 860

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	26/140 (19%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	129/507 (25%)
alg-2	NP_871992.1	ArgoN	75..205	CDD:465134	25/134 (19%)
		ArgoL1	215..273	CDD:462567	9/57 (16%)
		PAZ_argonaute_like	274..395	CDD:239212	26/132 (20%)
		Piwi_ago-like	440..866	CDD:240015	122/475 (26%)