Protein Alignment aub and alg-5

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001370006.1
• Gene: alg-5 / 172861
• WormBaseID: WBGene00011945
• Length: 905
• Species: Caenorhabditis elegans
• Alignment Length: 928
• Identity: 193/928 - (20%)
• Similarity: 362/928 - (39%)
• Gaps: 231/928 - (24%)

  Fly    60 PSIEKSSLSAVQMHKSEGDPRGSVRGRRLITDLVYSRP---------------PGMTSKKGVVGT 109
            ||:|...||             |..|.|:..|| |..|               |..|      |.
 Worm    35 PSLENEFLS-------------SSSGSRVSDDL-YLHPIEENREPFKLIGKPLPSTT------GR 79

  Fly   110 HITVQANYFKVLKRPNWTIYQYRVDFTPDVEATRLRRSFL----YEHKGILG-GYIFDG------ 163
            .:::.||:|::....: .|:||.:.|.||:.:.:|.|:.|    .::.|::. ..:|||
 Worm    80 FLSLLANHFQITCNGS-IIHQYYIRFDPDIPSKKLNRTILRTLQEQNPGLIECPLVFDGIHTVYS 143

  Fly   164 --------TNMFCINQFKAV--QDSPYVLELVTKSRAGENIEIKIKAVGSVQSTDAEQFQVLNLI 218
                    .|...||....|  ::||.:.:|.........::.||......|:........::.:
 Worm   144 TELINVKEVNNSVINVAGVVNTKESPNLFKLYLTHVDSFLLDTKIITGNQDQNQKLRMMHAIDTV 208

  Fly   219 LRRAMEGLDLKLVSRYYYDPQ------------AKINLENFRMQLWPGYQTSIRQHE----NDIL 267
            .|:...|....::..::...|            ..:||...|...:..||..:...:    |..:
 Worm   209 FRQTSTGNFHAVLQSFFSIAQNSAIEPSHGLGWGTVNLGVGREVCYGFYQNVVETFDTLTMNLDV 273

  Fly   268 LCSEICHKVMRTETLYNIL-------SDAIRDSDDYQSTFKRAVMGMVILTDYNN--KTYRIDDV 323
            ..:.....|...|.|..||       :|....||..:..|.|.|.|:.:.|.:.:  :.:|:...
 Worm   274 ATTTFYRPVALVEFLAEILEVPLATVTDGRSLSDVQKKKFNREVAGLKVETRHCSCPRRFRVARC 338

  Fly   324 DFQSTPLCKFKTND-------GEISYVDYYKKRYNIII-------------RDLKQPL----VMS 364
            .::.|....|..::       ..:|.|:|||:||||.:             |:...||    |:|
 Worm   339 TWKPTENISFHLSETAGNQDSKPLSLVEYYKRRYNIDLTYKHLPCIEVGRTRECILPLELCYVVS 403

  Fly   365 RPTDKNIRGGNDQAIMIIPELARATGMTDAMRADFRTLRAMSEHTRLNPDRRIERLRMFNKRLKS 429
              ..:.|:..|:|.   |..|.|||    :..|..|....||...||..|..:..::
 Worm   404 --GQRCIKKLNEQQ---IANLIRAT----SRNATERQNAVMSLQNRLKMDNDVNAVK-------- 451

  Fly   430 CKQSVETLKSWNIELDSALVEIPARVLPPEKILFGN-----QKIFVCDARADWTNEFRTCSMFKN 489
                      :.:::::.|::|..||||..::|:.:     |:.........|  :.|..:.:..
 Worm   452 ----------FGLKVEAQLLKIEGRVLPVPRLLYRSPNLKRQECVTVPNNGTW--DMRGKNFYSG 504

  Fly   490 VHINRWYVI---TP----SRNLRETQEFVQMCIRTASSMKMNICNPIYEEIPDDRNGTYSQAIDN 547
            :.|..|.::   :|    ..::|   .||:..:..||.:.|    |..||   .|...|:
 Worm   505 IQIREWAIVCFASPEIIGEASMR---SFVRNLVNVASEIGM----PFLEE---HRFCRYA----- 554

  Fly   548 AAANDPQIVMVVMRSPNEEKYSCIKKRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATKVV--- 609
                :|...:.::...||: |: ::...|:   ||.:    .|:....::...|:.:.|:.|
 Worm   555 ----EPDQTVKLLEHLNEQ-YN-LQLVLCI---VPGK----SVVYGELKRKGELLGLTTQCVRSQ 606

  Fly   610 --------------IQMNAKLMGAPWQVVIPLHGLMT--VGFDVCHSPKNK-------------- 644
                          :::|:||.|....:..|...|.:  |.|..||..::.
 Worm   607 NVSKASPHTLSNLCMKINSKLGGINVILSSPPQSLNSEPVLFIGCHLTRSSLASSSDSTSSIAHC 671

  Fly   645 NKSYGAFVATMDQKESFRYFSTVNEHIKGQELSEQMSVNMAC-----ALRSYQEQHRSLPERILF 704
            :.|....|.:||...:  .||.:   .:.|...::..|:| |     |:.::::.....|.:|:.
 Worm   672 DSSIACLVGSMDGHPT--QFSPI---FRTQPRHQRTIVDM-CEMTREAIINFRKSTGFKPHKIII 730

  Fly   705 FRDGVGDGQLYQVVNSEVNTLKDRLDEIYKSAGKQEGCRMTFIIVSKRINSRYF-------TGHR 762
            :|.|:.|..:.:::.:|:..::|....|  ..|.|.|  :|||.:....::|.|       .|:.
 Worm   731 YRAGIADVTVDEIMQTELRAVRDACAMI--EYGFQPG--ITFIGLDVTHHTRLFAANEKDRVGNS 791

  Fly   763 NPVP-GTVVDDVITLPERYDFFLVSQAVRIGTVSPTSYNVISDNMGLNADKLQMLSYKMTHMYYN 826
            ..|| ||:|:..||:...::|:|||.|...||..||.|.|:.|:..:.:..:..::|::.|....
 Worm   792 QNVPAGTLVETGITVNNLFEFYLVSHAGIQGTSRPTKYVVMWDDNSIPSADIHEMTYQLCHTQSR 856

  Fly   827 YSGTIRVPAVCHYAHKLA 844
            .:.::.:|:..:||..:|
 Worm   857 CTRSVSIPSPVYYAKLVA 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	38/152 (25%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	104/503 (21%)
alg-5	NP_001370006.1	ArgoL1	219..280	CDD:462567	7/60 (12%)
		PAZ	310..420	CDD:460472	26/114 (23%)
		Piwi_ago-like	448..881	CDD:240015	98/485 (20%)