Protein Alignment aub and vsra-1

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001417601.1
• Gene: vsra-1 / 172816
• WormBaseID: WBGene00007297
• Length: 946
• Species: Caenorhabditis elegans
• Alignment Length: 654
• Identity: 128/654 - (19%)
• Similarity: 236/654 - (36%)
• Gaps: 169/654 - (25%)

  Fly   286 LSDAIRDSDDYQSTFKRAVMGMVILTDYNNKTYRIDDVDFQSTPLCKFKTNDG--------EIS- 341
            |.|.|:..:..|  .:..:.|:.:.|.|::::..||.:  .:.|:.:.|..||        .:|
 Worm   317 LKDLIKGINPNQ--LRSYLKGLRVHTTYSHQSIFIDGI--SNVPIGEIKLPDGTPLLDDCARVSG 377

  Fly   342 -------------YVDYYKKR------YNIIIRDLKQPLVMSRPTDKNIRGGNDQAIMIIPELAR 387
                         .|:.|.||      |:..|.:|     :.:|..|..:...:....|.|||.
 Worm   378 KPKSFFDASKPAVQVNQYNKREGRRMVYSFPIENL-----LVKPNQKLTQNHGEPPRSIKPELR- 436

  Fly   388 ATGMTDAMRADFRTLRAMSEHTR-LNPDRRIERLRMFNKRLKSCKQSVETLKSWNIELDSALVEI 451
                       |..:|.:.|..: |:|:                    :||||..|.::...:.:
 Worm   437 -----------FDLIRKVGESAKLLSPN--------------------QTLKSIGIAINPEPIVV 470

  Fly   452 PARVLPPEKILFGNQKIFVCDA--RADWTNEFRTCSMFKN-----VHINRWYVITPSRNLRETQE 509
            .|..:|...||:.:......|.  |..|..:.|.....|.     :.||:..:      |..:|.
 Worm   471 EAMTVPKPTILYKDGAFTSPDLLNRTSWDVQARNHQSLKGGFVEPMKINKILI------LYNSQS 529

  Fly   510 FVQMCIRTASSMKMNICNPIYEEIPDDRNGTYSQAIDNAAANDPQIV------MVVMRS------ 562
            :.|...:.|.....:|.:...:::     |.....||....|||.|:      |.::::
 Worm   530 YSQASPKEAVVELQSILSKKAKDV-----GMTIGQIDVEDLNDPDIIGAIENKMTILKTSQVKPI 589

  Fly   563 ------PNEEKYSCIK--KRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATKVVIQMNAKLMGA 619
                  .:|..:|.:|  :|.|       :|:|.:|...:..|.|.....|..:::::|.|..|.
 Worm   590 VIYADHTSEGTHSTLKLQERLC-------EVITQQVALDKSLKRTPGKVTANNLLMKLNLKYGGV 647

  Fly   620 PWQV-----VIPLHG----LMTVGFDVCHSPKNKNK-----------SYG--------AFVATMD 656
            ..:|     :..|.|    .:.:.:|||||.....|           .:|        ||:.
 Worm   648 NHKVRVDNSISHLWGDTSNTLIISYDVCHSSGKVYKKDEICDEPSCVGFGFNGTACPEAFIG--- 709

  Fly   657 QKESFRY----FSTVNEHIKGQELSEQMSVNMACALRSYQEQHRSLPERILFFRDGVGDGQLYQV 717
               .|.|    ...|:||:        :.:.....|..|....:..|::::..||||.:||...|
 Worm   710 ---DFHYQLPRHEQVDEHL--------LKLRARFMLNHYITSRKKYPQQVVILRDGVSEGQHKMV 763

  Fly   718 VNSEVNTLKDRLDEIYKSAGKQEGCRMTFIIVSKR------INSRYFTGHRNPVPGTVVDDVITL 776
            .|.|...:|..:..::... |.:......::|:||      |..:..:|:.|..|.|.:|..|..
 Worm   764 RNEEFQAIKQSIMNVFNEK-KAKAPSFALLVVTKRHANRLLIKDQNVSGYTNVPPLTAIDQTIVK 827

  Fly   777 PERYDFFLVSQAVRIGTVSPTSYN-VISDNMGLNADKLQMLSYKMTHMYYNYSGTIRVPAVCHYA 840
            .:..:...||.....||..|...| :::|.:....|:|......:...:...:..:.:|...:.|
 Worm   828 KQGNEVIFVSHCPLNGTAQPIVINTLVNDGIFKTNDQLVQFITALCCAHQKSTNIVSLPESIYAA 892

  Fly   841 HKLA 844
            .:.|
 Worm   893 DEYA 896

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	27/133 (20%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	100/512 (20%)
vsra-1	NP_001417601.1	PRK12323	<13..231	CDD:481241
		Piwi	589..904	CDD:214930	67/330 (20%)