Protein Alignment aub and ppw-2

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_491535.1
• Gene: ppw-2 / 172152
• WormBaseID: WBGene00004094
• Length: 975
• Species: Caenorhabditis elegans
• Alignment Length: 1000
• Identity: 184/1000 - (18%)
• Similarity: 339/1000 - (33%)
• Gaps: 303/1000 - (30%)

  Fly    60 PSIEKSSLSAVQMHKS--------------EGDPRGSVRGRRLITDLVYSRPPGMTSKKGVVGTH 110
            |.:...:|.....||:              ..||:            :|..|    ::.|..|:.
 Worm    35 PPVPVPTLPVTSEHKTAHDACIKRLEQLEIPPDPK------------IYPSP----TEPGTFGSV 83

  Fly   111 ITVQANYFKVLKRPNWTIYQYRVDFTPDVEATR----------------------------LRR- 146
            ..|..|.|.|........|||.|..|.::.:.:                            |.|
 Worm    84 TEVLTNVFGVEVHKTSNFYQYSVHITAELSSKKEVTFTKKGKEDFIVHDRHEKCSAILFHALNRF 148

  Fly   147 ---------SFLYEHKGIL--GGYIFDG-------TNMFCIN----QFKAVQDSPYV-LELV-TK 187
                     ..:|:.:.||  ...:|:|       |.:|.||    ..|.:...|.: ||:. ||
 Worm   149 EDFFKSSENCIIYDGQSILFTSMNLFEGIPTGKIKTKVFQINGADTNLKDLMVLPCIKLEVFPTK 213

  Fly   188 SRAGENIEIKIKAVGSVQSTDAEQFQVLNLILRRAMEGLDLKLVSRYYYDPQAK-INLENFRM-- 249
            :..   :...::.:|  :.|.....:.:|:..::.   |||.: |:|.....:| :..|:.:|
 Worm   214 NPV---VNFSLEDIG--RRTSDSNIESVNMAYKQI---LDLAM-SQYAIRETSKCVVFEHGKMFF 269

  Fly   250 --------------------QLWPGYQTSI--------RQHENDILLCSEICHKV---------M 277
                                |:.||.:.::        |...|..::...:  ||         .
 Worm   270 INPLQEGYAPCDIVEVGDGKQMKPGLKKTLQFIEGPYGRNQNNPSIVIDGM--KVAFHMEQLVFQ 332

  Fly   278 RTETLYNILSDAIRDSDDYQSTFKRAVMGMVILTDYNNKT--YRIDDVDFQSTPLCKFK-TNDGE 339
            :..::.:.|::.|..|:  :......:.|:...::|..:|  ::|:.:..:.....:|: ...|.
 Worm   333 KLSSITSNLANGITGSE--RERCAAVIKGLDCHSNYRGRTRHHKIESIHHEGAATARFELEGGGT 395

  Fly   340 ISYVDYYKKRYNIIIRDLKQPLVMSRPTDKNIRGGND----QAIMIIP-ELARATGMTDAMRADF 399
            .:...|:|.:|.|.:|.....|::.:.     ||..:    :.|.|.| :..|.|..|.:
 Worm   396 CTVATYFKDKYKIQLRYPNANLIVCKE-----RGALNFYPMELITISPNQRVRITQQTSS----- 450

  Fly   400 RTLRAMSEHTRLNPDRRIERLRMFNKRLKSCKQSVETLKSWNIELDSALVEIPARVLPPEKILFG 464
            ::.|...|...| ||.| :||.|..|                         |.|::....::| |
 Worm   451 QSQRTTKESAVL-PDIR-QRLIMTGK-------------------------IAAKITAENEVL-G 487

  Fly   465 NQKIFVCD----ARADWTNEFRTCSMFKNVHI-------------NR-------WY---VITPSR 502
            ...:.|||    .:.......|..|.....|:             ||       |.   |.:|..
 Worm   488 KMGVTVCDEPLVVKGRNLPAIRLASFETGEHLINPRDCKWRPQRYNRSAVAPKVWALYGVGSPGS 552

  Fly   503 NL------RETQEFVQMCIRTASSMKMNICNPIYEEIPDDRNGTYSQAIDN---AAANDPQIVMV 558
            .:      |...||:.|      |....|..|    .|.|.|.....||:|   .|||.....::
 Worm   553 QMNRDVMRRFCDEFMNM------SRSKGILFP----PPGDVNLLTPDAIENRLREAANAGCTFVL 607

  Fly   559 VMRSPN----EEKYSCIKKRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATK-----VVIQMNA 614
            .:...|    .:||..|:..|        |::...:   :..|...:::.:.|     |:.:.|.
 Worm   608 CITEDNITCLHQKYKFIEHHT--------QMIVQDM---KLSKALSVVNASKKLTLENVINKTNV 661

  Fly   615 KLMGAPWQVV-----IPLHGLMTVGFD--------VCHSPKNKNKSYGAFVATMDQKESFRYFST 666
            ||.|:.:..:     :..|.::.||..        :..|....|.:...|....:.|:.|.....
 Worm   662 KLGGSNYVYLDTKNFLQEHLIIGVGISSPPPGTKYIMESRGILNPTIVGFAYNGNGKQEFSGDFV 726

  Fly   667 VNEHIKGQELSEQMSVNMACALRSYQEQH-RSLPERILFFRDGVGDGQLYQVVNSEVNTLKDRLD 730
            :|  ..|||....:...::.:::.|::.| ...|:||..:|.|..:|....:::.||...:..:.
 Worm   727 LN--AAGQETIAPIEDIVSYSIKGYKKFHDGKAPKRITIYRSGSSEGNHGPIISYEVPLARVAMR 789

  Fly   731 EIYKSAGKQEGCRMTFIIVSKRINSRYF--------TGHRNPV---------------------P 766
            ..      ....::.:|:|||....|:|        :|..|..                     |
 Worm   790 NF------SPDTQLLYIVVSKEHTYRFFKKESGGSSSGGSNSAGASNSGTLTSAPPKPWELNIGP 848

  Fly   767 GTVVDDVITLPERYDFFLVSQAVRIGTVSPTSYNVISDNMGLNADKLQMLSYKMTHMYYNYSGTI 831
            |..||..:|.|....|||.|.....|:.....|.|::|:..:....|:..::.:.|::.......
 Worm   849 GLTVDYGVTNPACKQFFLNSHMTLQGSAKTPLYTVLADDRNIGMSALEEFTFNLCHLHQIVGLPT 913

  Fly   832 RVPAVCHYAHKLA----FLVAESIN 852
            .:|...:.|::.|    .|..|:||
 Worm   914 SIPTPLYVANEYAKRGRNLWNEAIN 938

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	24/136 (18%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	104/540 (19%)
ppw-2	NP_491535.1	PAZ	334..461	CDD:198017	25/138 (18%)
		Piwi	604..934	CDD:396649	63/348 (18%)