Protein Alignment aub and sago-2

DIOPT Version :10

• Sequence 1: NP_476734.1
• Gene: aub / 34524
• FlyBaseID: FBgn0000146
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_490758.1
• Gene: sago-2 / 171653
• WormBaseID: WBGene00018921
• Length: 887
• Species: Caenorhabditis elegans
• Alignment Length: 920
• Identity: 186/920 - (20%)
• Similarity: 326/920 - (35%)
• Gaps: 272/920 - (29%)

  Fly   108 GTHITVQANYFKVLKRPNWTIYQYRVDFT-----PD-VEAT------------------------ 142
            ||.:.:..|..|:..:||..||:|.|...     || .|||
 Worm    38 GTKVNIDTNIRKLTIKPNQPIYKYAVQVNYVFRKPDGTEATIEMSKSAKKGTEHDNDKTRCQNVY 102

  Fly   143 --RLRR--------SFLYEHKGIL--------GGYIFDGTNMFCINQ-FKAVQDSPYVLELVTKS 188
              .::|        .|.|:.:..|        ....|..|:..|..| ||..|   :||:.|.:|
 Worm   103 NEAIKRYDELKTGGPFFYDRQASLYTLTKLKNESISFVVTDKICKRQNFKEAQ---FVLKKVDQS 164

  Fly   189 RAGENIEIKIKAVGSV-QSTDAEQFQVLNLILR-RAMEGLDLKLVS---RYYYDPQAKINL---E 245
            ....:.:: ||...|. .:.|....:.:|:|:. .|.|..::..|.   .|..||.. :::   |
 Worm   165 FQSTSNDV-IKTTNSCPANADKTLLEAMNIIVSGPAFENKNVITVGACVHYLIDPTG-VDVAYKE 227

  Fly   246 NFRMQLWP--GYQTSIRQHEN------DILLCSEICHKVMRTETL----YNILSDAIRDSDDYQS 298
            ....||:.  |...|::..|.      .:.:.:|     |:| ||    |..|.:.::....:.:
 Worm   228 YPEGQLYSGVGVSKSVKTLEGTDKKVPSLFMTTE-----MKT-TLFHPDYAPLVELLQTFRGFST 286

  Fly   299 TFK----------RAVMGMVILTDYN-NKTYRIDDVDFQSTPLCKFKTNDGEISY---------- 342
            |.|          :|.:|:.::.:|. :|....|.|..:   :.:|.|:..|..:
 Worm   287 TLKANSPAAQRIEKAFVGLDVVLNYGVHKGLGEDGVVMK---IRRFHTSAKETCFEVEKSTREFT 348

  Fly   343 --VDYYKKRYNIIIRDLKQPLVMSRPTDKNIRGG---NDQAIMIIPELARATGMTDAM----RAD 398
              .||:||:|.|   .||.|.:.:... |..:|.   ..:.:::.|   ..|...|.|    :||
 Worm   349 NVFDYFKKKYGI---TLKYPDLFTIEA-KGKQGKIHFPAEVLLLCP---NQTVTNDQMINNEQAD 406

  Fly   399 FRTLRAMSEHTRLNPDRRIERLRMFNKRLKSCKQSVETLKSWNIELDS------ALVEIPAR--- 454
            ...:.|...|.|                    |.:.:|:.. |:.|.|      ..||.|..
 Worm   407 MIKMSAAQPHIR--------------------KTTTDTIVR-NVGLASNNIYGFIKVEDPVNLEG 450

  Fly   455 -VLPPEKILF-GNQKIFVCDARADWTNEFRTCSMFKNV-HINRWYVITPSRNLRETQEFVQMCIR 516
             |||..||.| ||:...:.:.::.:..:|.....:.:. .:.:|.::     ..:.:|...:..:
 Worm   451 MVLPKPKIAFAGNRLADLANPKSRFPTDFNRAGQYYDAKELTKWELV-----FVQNEEVQGLAKQ 510

  Fly   517 TASSM---KMNICNPIYEEIPDDRNGTYSQAIDNAAANDPQIVMVVMRS---------PNEEKYS 569
            .|..|   .|...||....|   ..|........|.|...|::..|::|         ..|:||
 Worm   511 LADEMVNNGMKCSNPTMSFI---IRGDLEPIFKKAKAAGTQLLFFVVKSRYNYHQQIKALEQKY- 571

  Fly   570 CIKKRTCVDRPVPSQVVTLKVIAPRQQKPTGLMSIATKVVIQMNAKLMG-----------APWQV 623
                          .|:|.::.|...:|..........::.:.|.||.|           .|.::
 Worm   572 --------------DVLTQEIRAETAEKVFRQPQTRLNIINKTNMKLGGLNYAIGSEAFNKPNRL 622

  Fly   624 VIPLHGLMT-------------VGFDVCHSPKNKNKSYGAFVATMDQKESFRYFSTVNEHIKGQE 675
            ::   |.:|             ||| ..:..|:..|..|.:|.....::.|.  |.:.:.:
 Worm   623 IV---GFVTSQRVGGNPDYPISVGF-AANMLKHHQKFAGGYVYVHRDRDVFG--SIIKDTL---- 677

  Fly   676 LSEQMSVNMACALRSYQEQHRSLPERILFFRDGVGDGQLYQVVNSEVNTLKDRLDEIYKSAGKQE 740
                :::...|.      :.|..|:.||.:.:||.:|| :.::|.|.            ||..:|
 Worm   678 ----LTIFKTCT------EQRGRPDDILLYFNGVSEGQ-FSMINEEF------------SARVKE 719

  Fly   741 GC-------------RMTFIIVSKRINSRYFTGHR----NPVPGTVVDDVITLPERYDFFLVSQA 788
            .|             .:|.|..||..|.|.:...:    |..||||||..|......:::..|..
 Worm   720 ACMAFQKEGTPPFRPHITIIASSKAHNERLYKSDKGRIVNLEPGTVVDHTIVSNVYTEWYHASAV 784

  Fly   789 VRIGTVSPTSYNVI-SDNMGLNADKLQMLSYKMTHMYYNYS---GTIRVPAVCH----YAHKLAF 845
            .|.||...|.:.:| :...|..|:.|..|......:.|::.   ..:.:|...:    |:.:.|.
 Worm   785 ARQGTAKATKFTLIFTTKAGPQAEPLWHLEQLTNDLCYDHQIVFHPVGLPVPLYIADRYSQRGAM 849

  Fly   846 LVAESINRAP 855
            ::|  .|:.|
 Worm   850 VLA--ANQGP 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aub	NP_476734.1	PAZ_piwi_like	272..392	CDD:239211	30/149 (20%)
		Piwi_piwi-like_Euk	400..849	CDD:240016	100/521 (19%)
sago-2	NP_490758.1	PAZ_argonaute_like	272..389	CDD:239212	23/123 (19%)
		Piwi-like	444..849	CDD:239208	89/460 (19%)