Protein Alignment SCAR and Wasf3

DIOPT Version :9

• Sequence 1: NP_001260368.1
• Gene: SCAR / 34519
• FlyBaseID: FBgn0041781
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_038945859.1
• Gene: Wasf3 / 682937
• RGDID: 1592807
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 679
• Identity: 224/679 - (32%)
• Similarity: 296/679 - (43%)
• Gaps: 188/679 - (27%)

  Fly     1 MPLPKRSIEPVHVARSVYQQDELQSVELETVTNTTLTNIIRQLSSLSKHAEDVFGELARDVGNIG 65
            |||.||:|||.|:.|...  .|..:.|||.|||:||..||||||||||||||:||||..:..|..
  Rat     1 MPLVKRNIEPRHLCRGAL--PEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEANNFY 63

  Fly    66 DRANSLQARIDRLAIKVTQLDSTVEEVPLTDITRKKAFKSAKVFDQQIFSRATMPAPMMDTYAQC 130
            .||||||.||||||:||||||||||||.|.||..||||||:.:.|||:.|:.::|.|:.|.|.|.
  Rat    64 IRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTIQDQQVVSKNSIPNPVADIYNQS 128

  Fly   131 DKPPPLDKLNVYRDDGKDGLKFYTDPNYFFELWRQEMLKDTERVMHDKGKKLNRPRQDGGAGGAA 195
            ||||||..|..||||.||||||||||:|||:||:::||:|||....:|.::..:.|.|
  Rat   129 DKPPPLSILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQKEQKRVD------- 186

  Fly   196 GRGNKKQKTKIRVPHNTREQQRQRALVHGETLMPNNVIYRTPNSMVNEEAGYGIQLVKIQTVGEA 260
              |..::..|:|...|.|::....|  :.:.|.|:|.:.::.:...:.|             |..
  Rat   187 --GTTREVKKVRKARNRRQEWNMMA--YDKELRPDNRLSQSVHHGASSE-------------GSL 234

  Fly   261 DIDLRHSTLDAHHQVVGNIQDVDTVKPYNMLSHLENNSNVTKQTAVAIADMGVYDTRPPRPNSIE 325
            ..|.|..|.|              |..|:                        |...|
  Rat   235 SPDTRSHTSD--------------VTDYS------------------------YPATP------- 254

  Fly   326 LNRSYQSEQIDGSTYEQLPPQMGNQYAATFGNGMGGPQQMHMQHQQMYDAGMYQSHALYGQTGQG 390
             |.:.|.:.:..|                                  |.||....||   .|.||
  Rat   255 -NHALQVQPVTPS----------------------------------YTAGDAPLHA---ATNQG 281

  Fly   391 VMSPEPIYGPGTPSRNK---PRPSQPPPAPPSNGSGGGTPTASNANTPTR--------GRSMSTS 444
            .   |..|.|.:.|...   .||.||||.||..     .|..|.|:|...        .:.:...
  Rat   282 A---EHEYRPSSASARHMALNRPQQPPPPPPPQ-----APDGSQASTSVAPADYGMLPAQIIEYY 338

  Fly   445 RDALPPPPPVPDVISPMSGMNGVNSGHMAAKLLGRANSSSGAGSPNSVQNANDMVMTQLSNTFHS 509
            ..:.|||||.|.:|                     .::.:...||..:............:|:
  Rat   339 NPSGPPPPPPPPMI---------------------PSAQTAFVSPLQIPAQQPSFPASTGSTY-- 380

  Fly   510 IGMTGNQLNSLSDLPPPPPVPDQHSPKMSPPNAAPPPPPPPPPVEEGMGSGNQHTLRPHQILPKS 574
                          |.||..|.......:||...||||||.||.                  |.|
  Rat   381 --------------PTPPHQPSTGLLATAPPPPGPPPPPPGPPG------------------PSS 413

  Fly   575 LANGEMQQPGQQNGVPHIVAPKKMLPPFHDPRNDLMKAIRDGITLRKVEKSEQKEIERNAAPLDV 639
            |::..|..|    .|.....|:...||..|.|:||:.|||.||.|:||::..::|.:|.....||
  Rat   414 LSSSPMHGP----PVAEAKRPEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDV 474

  Fly   640 ASILARRVAIELSESEDSDSEDDSEGWME 668
            |:||:||:|:|.|:|:| |||.|...|.:
  Rat   475 ATILSRRIAVEYSDSDD-DSEFDENDWSD 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCAR	NP_001260368.1	None
Wasf3	XP_038945859.1	WH2	437..502	CDD:425359	31/65 (48%)
		actin-binding sequence	454..457	CDD:409196	1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	288	1.000	Inparanoid score	I2736
OMA	1	1.010	-	-		QHG54445
OrthoDB	1	1.010	-	-		D1183697at2759
OrthoFinder	1	1.000	-	-		FOG0000853
OrthoInspector	1	1.000	-	-		otm46149
orthoMCL	1	0.900	-	-		OOG6_106458
Panther	1	1.100	-	-	LDO	PTHR12902
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X835
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.980