Protein Alignment SCAR and wasf3b

DIOPT Version :10

• Sequence 1: NP_001260368.1
• Gene: SCAR / 34519
• FlyBaseID: FBgn0041781
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001074059.1
• Gene: wasf3b / 563632
• ZFINID: ZDB-GENE-070112-1512
• Length: 481
• Species: Danio rerio
• Alignment Length: 698
• Identity: 226/698 - (32%)
• Similarity: 295/698 - (42%)
• Gaps: 247/698 - (35%)

  Fly     1 MPLPKRSIEPVHVARSVYQQDELQSVELETVTNTTLTNIIRQLSSLSKHAEDVFGELARDVGNIG 65
            |||.||:|||.|:.|.|.  .|....|||.|.|.||:.||||||||||||||:||||..:.....
Zfish     1 MPLVKRNIEPRHLCRGVL--PEGIGSELECVMNNTLSAIIRQLSSLSKHAEDIFGELFNEANMFY 63

  Fly    66 DRANSLQARIDRLAIKVTQLDSTVEEVPLTDITRKKAFKSAKVFDQQIFSRATMPAPMMDTYAQC 130
            .||||||.||||||:||||||||||||.|.||..:|||||:.:.|||:.|::::|.|:.:.|...
Zfish    64 LRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMRKAFKSSTIQDQQVVSKSSVPIPVTEMYNLS 128

  Fly   131 DKPPPLDKLNVYRDDGKDGLKFYTDPNYFFELWRQEMLKDTERVMHDKGKKLNRPRQ-----DGG 190
            ||||||:.|..||||.|:||||||||:|||:||:::||:|||    ||.|:..|.::     ||.
Zfish   129 DKPPPLNILTPYRDDDKEGLKFYTDPSYFFDLWKEKMLQDTE----DKRKEKRRQKEQRRCVDGT 189

  Fly   191 AGGAAGRGNKKQKTKIRVPHNTREQQRQRALVHGETLMPNNVIYRTPNSMVNEEAGYGIQLVKIQ 255
            .        :::..|:|...|.|::....|.  .:.|.|
Zfish   190 L--------QREVKKVRKARNRRQEWNMMAF--DKELRP-------------------------- 218

  Fly   256 TVGEADIDLRHS-----------TLDAHHQVVGNIQDVDTVKPYNMLSHLENNSNVTKQTAVAIA 309
                   |||||           |:...|:..|:..|...:...|.:.|
Zfish   219 -------DLRHSHTVHRGGSTEGTMSPEHRSHGDHADHGYLSMANHVGH---------------- 260

  Fly   310 DMGVYDTRPPRPNSIELNRSYQSEQIDGSTYEQLPPQMGNQYAATFGNGMGGPQQMHMQHQQMYD 374
                                       ..||...||.|....|.|           ||...|.|.
Zfish   261 ---------------------------AHTYSGPPPSMAALSAHT-----------HMSLDQDYR 287

  Fly   375 AG--MYQSHALYGQTGQGVMSPEPIYGPGTPSRNKPRPSQPPPAPPS----NGSGGGTPTASNAN 433
            :|  .|:|    |..|                    ||.|.||.||:    |||....|...:.:
Zfish   288 SGSMAYRS----GTLG--------------------RPHQAPPPPPASHTINGSMTLPPVDYSVD 328

  Fly   434 TPTRGRSMSTSRDALPPPPPV------PDVISPMSGMNGVNSGHMAAKLLGRANSSSGAGSPNSV 492
            ....|:        |||||.|      |..:.||.  :|...||     :|...:.:|..
Zfish   329 YMNSGQ--------LPPPPAVIPSAQTPFAMPPMG--SGPPPGH-----IGPMGAMAGYA----- 373

  Fly   493 QNANDMVMTQLSNTFHSIGMTGNQLNSLSDLPPPPPVPDQHSPKMSPPNAAPPPP--PPPPPVEE 555
                                           ||.||.        |.|.||||||  |||||
Zfish   374 -------------------------------PPIPPT--------SGPMAAPPPPVAPPPPP--- 396

  Fly   556 GMGSGNQHTLRPHQILPKSLANGEMQQPGQQNGVPHIVAPKKMLPPFHDPRNDLMKAIRDGITLR 620
               |..|      .|.||        :|...|..          .|..|.|:||:.|||.||.|:
Zfish   397 ---SAIQ------SITPK--------RPSVPNEA----------QPISDARSDLLAAIRMGIQLK 434

  Fly   621 KVEKSEQKEIERNAAPLDVASILARRVAIELSESEDSDSEDDSEGWME 668
            ||::.::::.:|.....|||:||:||:|:|.|:||| :||.:...|.:
Zfish   435 KVQEQQEQQAKREPVGNDVATILSRRIAVEYSDSED-ESELEDNDWSD 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCAR	NP_001260368.1	WH2	599..>650	CDD:425359	22/50 (44%)
wasf3b	NP_001074059.1	WH2_WAVE-3	416..481	CDD:409216	29/65 (45%)
		actin-binding sequence	433..436	CDD:409216	1/2 (50%)