Protein Alignment SCAR and zgc:109889

DIOPT Version :10

• Sequence 1: NP_001260368.1
• Gene: SCAR / 34519
• FlyBaseID: FBgn0041781
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001314967.1
• Gene: zgc:109889 / 553542
• ZFINID: ZDB-GENE-050522-547
• Length: 540
• Species: Danio rerio
• Alignment Length: 708
• Identity: 234/708 - (33%)
• Similarity: 320/708 - (45%)
• Gaps: 208/708 - (29%)

  Fly     1 MPLPKRSIEPVHVARSVYQQDELQSVELETVTNTTLTNIIRQLSSLSKHAEDVFGELARDVGNIG 65
            |||.||||||.|:.|... .|.:.| |||.|||:||..||:||.|||:||||:||||..:..:..
Zfish     1 MPLVKRSIEPKHLCRGAL-PDGVPS-ELECVTNSTLAAIIKQLGSLSRHAEDIFGELFNEANSFY 63

  Fly    66 DRANSLQARIDRLAIKVTQLDSTVEEVPLTDITRKKAFKSAKVFDQQIFSRATMPAPMMDTYAQC 130
            .|.|:||.|:|.|||||||||||||||.|.||..:|||||:.:.|||:.||.::|.|:::.|.:.
Zfish    64 MRMNNLQERVDLLAIKVTQLDSTVEEVSLQDINMRKAFKSSTIQDQQVVSRNSIPNPVLELYHRG 128

  Fly   131 DKPPPLDKLNVYRDDGKDGLKFYTDPNYFFELWRQEMLKDTERVMHDKGKKLNRPRQDGGAGGAA 195
            ||||||:.|:.||||.||.|||||||:|||.|||::||:.||    ||.|:..|.:..|     :
Zfish   129 DKPPPLNILSPYRDDKKDALKFYTDPSYFFILWREKMLQATE----DKRKEKRRQKTSG-----S 184

  Fly   196 GRGNKKQKTK-------IRVPHNTREQQRQRALVHGETLMPNNVIYRTPNSMVNEEAGYGIQLVK 253
            |:.:..| ||       :|.|..:.|||:|       ...|:..:.:...:. |....:.:...
Zfish   185 GQTHSDQ-TKSHSRQALLRSPLLSSEQQKQ-------VEDPSREVKKVRKAR-NRRQEWNVMAY- 239

  Fly   254 IQTVGEADIDLRHSTLDAHHQVVGNIQDVDTVKPYNMLSHLENNSNVTKQTAVAIADMG--VYDT 316
                   |.:.|.   ||..          |..||:.:|   :..:::.......:|||  .|..
Zfish   240 -------DKEFRP---DARF----------TPSPYHGMS---SEGSLSPDNRSVASDMGEHSYPG 281

  Fly   317 RPPRP-NSIELNRSYQSEQIDGSTYEQLPPQMGNQYAATFGNGMGGPQQMHMQHQQMYDAGMYQ- 379
            .|..| ..:.::.:|.:  .||..:...|                    .|:|.|.: |.| |:
Zfish   282 SPSHPAQQMAVSSAYSA--ADGKEHLMAP--------------------SHVQTQSL-DRG-YRP 322

  Fly   380 ---SHALYG-------QTGQGVMSPEPIYGPGTPSRNKPRPSQP---------------PPAPPS 419
               |.|..|       ||..|    :||   ..|:.|.|||.|.               |||||
Zfish   323 APSSAAPPGRQTIGRVQTSHG----QPI---TDPALNGPRPLQTKDYSGQQSQHREYFVPPAPP- 379

  Fly   420 NGSGGGTPTASNANTPTRGRSMSTSRDALPPPPPVPDVISPMSGMNGVNSGHMAAKLLGRANSSS 484
                                         ||||.:|                         ::.:
Zfish   380 -----------------------------PPPPLIP-------------------------SAQT 390

  Fly   485 GAGSPNSVQNANDMVMTQLSNTFHSIGMTGNQLNSLSDLPPPPPVPDQHSPKMS-PPNAAPPPPP 548
            ...||....:|....|..||.|:             |..||.|.:|..::|..: ||.|||||||
Zfish   391 AFDSPTGPSSAPASAMPSLSQTY-------------SQSPPTPALPASYTPSPTHPPPAAPPPPP 442

  Fly   549 PPPPVEEGMGSGNQHTLRPHQILPKSLANGEMQQPGQQNGVPHIVAPKK---MLPPFHDPRNDLM 610
            |.||.            .||   |..:....::.|         |.|:|   .|.|..|.|:||:
Zfish   443 PGPPT------------HPH---PHPMPAASVEAP---------VVPRKGQVPLIPMSDARSDLL 483

  Fly   611 KAIRDGITLRKVEKSEQKEIERNAAPLDVASILARRVAIELSESEDSDSEDDSEGWME 668
            .|||.||.||||::..::|.::.....|||:||:||:|:|.||| |.|||.|...|.:
Zfish   484 AAIRRGIQLRKVQEQREQEAKKEPVGNDVATILSRRIAVEYSES-DEDSELDENEWSD 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCAR	NP_001260368.1	WH2	599..>650	CDD:425359	24/50 (48%)
zgc:109889	NP_001314967.1	WH2_WAVE-3	475..540	CDD:409216	32/65 (49%)
		actin-binding sequence	492..495	CDD:409216	2/2 (100%)