Protein Alignment SCAR and wasf2

DIOPT Version :10

• Sequence 1: NP_001260368.1
• Gene: SCAR / 34519
• FlyBaseID: FBgn0041781
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001315119.1
• Gene: wasf2 / 394056
• ZFINID: ZDB-GENE-040426-865
• Length: 486
• Species: Danio rerio
• Alignment Length: 675
• Identity: 224/675 - (33%)
• Similarity: 299/675 - (44%)
• Gaps: 196/675 - (29%)

  Fly     1 MPLPKRSIEPVHVARSVYQQDELQSVELETVTNTTLTNIIRQLSSLSKHAEDVFGELARDVGNIG 65
            |||..|:|||.|:.|... .:.::| |||.|||.||.||||||.||||:||||||||........
Zfish     1 MPLVTRNIEPRHLCRQTL-PNTIKS-ELECVTNITLANIIRQLGSLSKYAEDVFGELFVQASKFA 63

  Fly    66 DRANSLQARIDRLAIKVTQLDSTVEEVPLTDITRKKAFKSAKVFDQQIFSRATMPAPMMDTYAQC 130
            ||..:|..|:|:|.:||||||...|||.|..||.:|||.|..:.|||:|.||::|.|:.|||..|
Zfish    64 DRVTTLGERVDKLQVKVTQLDPKEEEVSLQAITSRKAFHSNLIQDQQLFIRASLPQPINDTYLTC 128

  Fly   131 DKPPPLDKLNVYRDDGKDGLKFYTDPNYFFELWRQEMLKDTERVMHDKGKKLNRPRQDGGAGGAA 195
            |:|||||||:.||:|||:.|||||||:|||:||:::||:||:.::.:|.|  ::.::|..    .
Zfish   129 DQPPPLDKLSPYREDGKEALKFYTDPSYFFDLWKEKMLQDTKDIIKEKRK--HKKKKDDN----V 187

  Fly   196 GRGNKKQKTKIRVPHNTREQQRQRALVHGETLMPNNVIYRTPNSMVNEEAGYGIQLVKIQTVGEA 260
            .|.|...: ||:    ||:.:.:|..:..|.::|........:..:|            .::|..
Zfish   188 NRRNLNPR-KIK----TRKDEWERQKMGAEFVVPKTDALGNSSEALN------------GSIGSG 235

  Fly   261 DIDLRHSTLDAHHQVVGNIQDVDTVKPYNMLSHLENNSNVTKQTAVAIADMGVYDTRPPRPNSIE 325
            |....|:.                       |:||.::|...           ||...|.|...:
Zfish   236 DDGYMHTD-----------------------SYLEQSTNSYS-----------YDPGSPLPPPAQ 266

  Fly   326 LNRSYQSEQIDGSTYEQL--PPQMGNQYAATFGNGMGGPQQMHMQHQQMYDAGMYQSHALYGQTG 388
                           |..  ||....||     |..||                  :|...|
Zfish   267 ---------------EDFPPPPPADTQY-----NESGG------------------AHTKRG--- 290

  Fly   389 QGVMSPEPIYGPGTPSRNKPRPSQPPPAPPSNGSGGGTPTASNANTPTRGRSMSTSRDALPPPPP 453
             .|:|                ||.|||||||..|..|..|.:....|             |||||
Zfish   291 -SVLS----------------PSHPPPAPPSMPSSPGRLTMAPPLAP-------------PPPPP 325

  Fly   454 VPDVISPMSGMNGVNSGHMAAKLLGRANSSSGAGSPNSVQNANDMVMTQLSNTFHSIGMTGNQLN 518
            ...:|.|...:                    |..||.|..                 ..|||.::
Zfish   326 PGGMIPPPPPL--------------------GFDSPPSPP-----------------PFTGNAVS 353

  Fly   519 SLSDLPPPPPVPDQHSPKMSPPNAA----PPPPPPPPPVEEGMGSGNQHTLRPHQILPKSLANGE 579
                :|||||: |...|...||..|    |||||||||.....|.            |...|.|
Zfish   354 ----IPPPPPM-DLSIPAPPPPPMAGGPPPPPPPPPPPGPPPPGP------------PPPSAPG- 400

  Fly   580 MQQPGQQNGVPHIVAPK-KMLPPFHDPRNDLMKAIRDGITLRKVEKSEQKEIERNAAPLDVASIL 643
               |....||....||| :..|...|.|:||:.|||.|..|||||:..::| :|:....|||:||
Zfish   401 ---PPPSAGVSAPSAPKAQPAPAAGDARSDLLAAIRQGFNLRKVEEQREQE-KRDHNGNDVAAIL 461

  Fly   644 ARRVAIELSESEDSDSEDDSEGWME 668
            :||:|:|.|:|||..||.|.:.|.:
Zfish   462 SRRIAVECSDSEDDSSEFDDDDWSD 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCAR	NP_001260368.1	WH2	599..>650	CDD:425359	24/50 (48%)
wasf2	NP_001315119.1	WH2	423..>468	CDD:425359	23/45 (51%)