Protein Alignment SCAR and Wasf2

DIOPT Version :9

• Sequence 1: NP_001260368.1
• Gene: SCAR / 34519
• FlyBaseID: FBgn0041781
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001013185.1
• Gene: Wasf2 / 313024
• RGDID: 1307299
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 688
• Identity: 208/688 - (30%)
• Similarity: 289/688 - (42%)
• Gaps: 211/688 - (30%)

  Fly     1 MPLPKRSIEPVHVARSVYQQDELQSVELETVTNTTLTNIIRQLSSLSKHAEDVFGELARDVGNIG 65
            |||..|:|||.|:.|.....|   :.|||..||.||.|:||||.||||:|||:|||:........
  Rat     1 MPLVTRNIEPRHLCRQTLPSD---TSELECRTNITLANVIRQLGSLSKYAEDIFGEICTQASAFA 62

  Fly    66 DRANSLQARIDRLAIKVTQLDSTVEEVPLTDITRKKAFKSAKVFDQQIFSRATMPAPMMDTYAQC 130
            .|.|||..|:||:.:||||||...|||.|..|..:|||:|:.:.||::|.|.::|.|:::||..|
  Rat    63 SRVNSLAERVDRVQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVPVLETYNSC 127

  Fly   131 DKPPPLDKLNVYRDDGKDGLKFYTDPNYFFELWRQEMLKDTERVMHDKGKKLNRPRQDGGAGGAA 195
            |.||||:.|:.||||||:.|||||:|:|||:||:::||:||:.:|.:| :|..:.::|.     .
  Rat   128 DAPPPLNNLSPYRDDGKEALKFYTNPSYFFDLWKEKMLQDTKDIMKEK-RKHRKEKKDN-----P 186

  Fly   196 GRGN-KKQKTKIRVPHNTREQQRQRALVHGETLMPNN----VIYRTPNSMVNEEAGYGIQLVKIQ 255
            .||| ..:|.|.|.....:.:..|..:...|.|.|:.    ::|:..|
  Rat   187 NRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGPSGYSPALVYQNGN----------------- 234

  Fly   256 TVGEADIDLRHSTLDAHHQVVGNIQDVDTVK----PYNMLSHLENNSNVTKQTAVAIADMGVYDT 316
                                .|::::||...    |         .|:.....:.:.:|    |.
  Rat   235 --------------------FGSVENVDATSYPPPP---------QSDSASSPSPSFSD----DN 266

  Fly   317 RPPRPNSIELNRSYQSEQIDGSTYEQLPPQMGNQYAATFGNGMGGPQQMHMQHQQMYDAGMYQSH 381
            .||.|...    ||.::...||.                   :.||::..|         :..||
  Rat   267 LPPPPAEF----SYPADNQRGSV-------------------LAGPKRTSM---------VSPSH 299

  Fly   382 ALYGQTGQGVMSPEPIYGPGTPSRNKPRPSQPPPAPPSNGSGG-GTPTASNANTPTRGRSMSTSR 445
            ............|:|.:.| .|:...|.|...||..||.|.|. |||
  Rat   300 PPPAPPLSSPPGPKPGFAP-PPAPPPPPPMSVPPPLPSVGFGSPGTP------------------ 345

  Fly   446 DALPPP-----PPVPDVISPMSGMNGVNSGHMAAKLLGRANSSSGAGSPNSVQNANDMVMTQLSN 505
               |||     ||.||..:|
  Rat   346 ---PPPSPPSFPPHPDFAAP--------------------------------------------- 362

  Fly   506 TFHSIGMTGNQLNSLSDLPPPPPVPDQHSPKMSPP-----NAAPPPPPPPPPVEEGMGSGNQHTL 565
                              |||||.|....|...||     ..||||||||||...
  Rat   363 ------------------PPPPPPPAADYPMPPPPLSQPSGGAPPPPPPPPPPGP---------- 399

  Fly   566 RPHQILPKSLANGEMQQPGQQNGVPHIVAPKKMLPPFHDPRNDLMKAIRDGITLRKVEKSEQKEI 630
               ..||...|:|:...| ....|.....||..||...|.|:||:.|||.|..||:||:..::|
  Rat   400 ---PPLPLGGADGQPAAP-PPPPVSDAAKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQE- 459

  Fly   631 ERNAAPLDVASILARRVAIELSESEDSDSEDDSEGWME 668
            :|:....|||:||:||:|:|.|:|||..||.|.:.|.:
  Rat   460 KRDVVGNDVATILSRRIAVEYSDSEDDSSEFDEDDWSD 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCAR	NP_001260368.1	None
Wasf2	NP_001013185.1	WH2	427..>478	CDD:425359	23/51 (45%)
		actin-binding sequence	449..452	CDD:409196	2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353962
Domainoid	1	1.000	288	1.000	Domainoid score	I1511
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	288	1.000	Inparanoid score	I2736
OMA	1	1.010	-	-		QHG54445
OrthoDB	1	1.010	-	-		D1183697at2759
OrthoFinder	1	1.000	-	-		FOG0000853
OrthoInspector	1	1.000	-	-		otm46149
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12902
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X835
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.010