Protein Alignment SCAR and Wasf3

DIOPT Version :9

• Sequence 1: NP_001260368.1
• Gene: SCAR / 34519
• FlyBaseID: FBgn0041781
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_660137.1
• Gene: Wasf3 / 245880
• MGIID: 2658986
• Length: 501
• Species: Mus musculus
• Alignment Length: 683
• Identity: 228/683 - (33%)
• Similarity: 298/683 - (43%)
• Gaps: 197/683 - (28%)

  Fly     1 MPLPKRSIEPVHVARSVYQQDELQSVELETVTNTTLTNIIRQLSSLSKHAEDVFGELARDVGNIG 65
            |||.||:|||.|:.|...  .|..:.|||.|||:||..||||||||||||||:||||..:..|..
Mouse     1 MPLVKRNIEPRHLCRGAL--PEGVTSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEANNFY 63

  Fly    66 DRANSLQARIDRLAIKVTQLDSTVEEVPLTDITRKKAFKSAKVFDQQIFSRATMPAPMMDTYAQC 130
            .||||||.||||||:||||||||||||.|.||..||||||:.:.|||:.|:.::|.|:.|.|.|.
Mouse    64 IRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTIQDQQVVSKNSIPNPVADIYNQS 128

  Fly   131 DKPPPLDKLNVYRDDGKDGLKFYTDPNYFFELWRQEMLKDTERVMHDKGKKLNRPRQDGGAGGAA 195
            ||||||..|..||||.||||||||||:|||:||:::||:|||....:|.::..:.|.|
Mouse   129 DKPPPLSILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQKEQKRVD------- 186

  Fly   196 GRGNKKQKTKIRVPHNTREQQRQRALVHGETLMPNNVIYRTPNSMVNEEAGYGIQLVKIQTVGEA 260
              |..::..|:|...|.|::....|  :.:.|.|:|.:.::.:...:.|             |..
Mouse   187 --GTTREVKKVRKARNRRQEWNMMA--YDKELRPDNRLSQSVHHGASSE-------------GSL 234

  Fly   261 DIDLRHSTLDAHHQVVGNIQDVDTVKPYNMLSHLENNSNVTKQTAVAIADMGVYDTRPPRPNSIE 325
            ..|.|..|.|              |..|:                        |...|
Mouse   235 SPDTRSHTSD--------------VTDYS------------------------YPATP------- 254

  Fly   326 LNRSYQSEQIDGSTYEQLPPQMGNQYAATFGNGMGGPQQMHMQHQQMYDAGMYQSHALYGQTGQG 390
             |.:.|::....|                                  |.||   ...|:|.|.||
Mouse   255 -NHALQAQPATPS----------------------------------YTAG---DAPLHGTTNQG 281

  Fly   391 VMSPEPIYGPGTPSRNK---PRPSQPPPAPPSNGSGGGTPTASNANTPTR--------GRSMSTS 444
            .   |..|.|.:.|...   .||.||||.||..     .|..|.|:|...        .:.:...
Mouse   282 A---EHEYRPSSASARHMALNRPQQPPPPPPPQ-----APEGSQASTSVAPADYGMLPAQIIEYY 338

  Fly   445 RDALPPPPPVPDVISPMSGMNGVNSGHMAAKLLGRANSSSGAGSPNSVQNANDMVMTQLSNTFHS 509
            ..:.|||||.|.:|.                               |.|.|           |.|
Mouse   339 SPSGPPPPPPPPMIP-------------------------------SAQTA-----------FVS 361

  Fly   510 IGMTGNQ----LNSLSDLPPPPPVPDQHSPKMSPPNAAPPPPPPPPPVEEGMGSGNQHTLRPHQI 570
            ......|    .:::|..|.||..|.......:||...||||||.||.
Mouse   362 PLQMPTQPPFPASAVSTYPTPPHQPSTGLLATAPPPPGPPPPPPGPPG----------------- 409

  Fly   571 LPKSLANGEMQQPGQQNGVPHIVAPKKMLPPFHDPRNDLMKAIRDGITLRKVEKSEQKEIERNAA 635
             |.||::..|..|    .|.....|:...||..|.|:||:.|||.||.|:||::..::|.:|...
Mouse   410 -PSSLSSSPMHGP----PVAEAKRPEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPV 469

  Fly   636 PLDVASILARRVAIELSESEDSDSEDDSEGWME 668
            ..|||:||:||:|:|.|:|:| |||.|...|.:
Mouse   470 GNDVATILSRRIAVEYSDSDD-DSEFDENDWSD 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCAR	NP_001260368.1	None
Wasf3	NP_660137.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..443		89/451 (20%)
		WH2	439..456	CDD:128542	9/16 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850266
Domainoid	1	1.000	229	1.000	Domainoid score	I2463
eggNOG	1	0.900	-	-		E1_KOG1830
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3078
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54445
OrthoDB	1	1.010	-	-		D1183697at2759
OrthoFinder	1	1.000	-	-		FOG0000853
OrthoInspector	1	1.000	-	-		otm44059
orthoMCL	1	0.900	-	-		OOG6_106458
Panther	1	1.100	-	-	LDO	PTHR12902
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4420
SonicParanoid	1	1.000	-	-		X835
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.800