Protein Alignment SCAR and SCAR

DIOPT Version :10

• Sequence 1: NP_001260368.1
• Gene: SCAR / 34519
• FlyBaseID: FBgn0041781
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_061517179.1
• Gene: SCAR / 1277451
• VectorBaseID: AGAMI1_009440
• Length: 654
• Species: Anopheles gambiae
• Alignment Length: 753
• Identity: 399/753 - (52%)
• Similarity: 464/753 - (61%)
• Gaps: 178/753 - (23%)

  Fly     1 MPLPKRSIEPVHVARSVYQQDELQSVELETVTNTTLTNIIRQLSSLSKHAEDVFGELARDVGNIG 65
            ||||||.::||.||||||.::||.: |||||||||||||:||||||||||||:|||||||.|.:.
Mosquito     1 MPLPKRLVQPVFVARSVYVREELPA-ELETVTNTTLTNIVRQLSSLSKHAEDLFGELARDAGGLA 64

  Fly    66 DRANSLQARIDRLAIKVTQLDSTVEEVPLTDITRKKAFKSAKVFDQQIFSRATMPAPMMDTYAQC 130
            :||||||||||||||||||||||||||.|.||..|||||||.:||||||||||||:.|::.|..|
Mosquito    65 ERANSLQARIDRLAIKVTQLDSTVEEVSLQDIQMKKAFKSATMFDQQIFSRATMPSAMLEVYKTC 129

  Fly   131 DKPPPLDKLNVYRDDGKDGLKFYTDPNYFFELWRQEMLKDTERVMHDKGKKLNRPRQDGGAGGAA 195
            ||||||||||.||||||||||||||||||||||||||||||||||||:|||:::||.||||.|..
Mosquito   130 DKPPPLDKLNCYRDDGKDGLKFYTDPNYFFELWRQEMLKDTERVMHDRGKKVHKPRADGGADGGG 194

  Fly   196 GRGNKKQKTKIRVPHNTREQQRQRALVHGETLMPNNVIYRTPNSMV--NEEAGYGIQLVKIQTVG 258
                 :||.:.|.||||||:|||||:.||||||||||||||||:::  .|||.|
Mosquito   195 -----RQKKRPRAPHNTREKQRQRAIGHGETLMPNNVIYRTPNAIIGSQEEAIY----------- 243

  Fly   259 EADIDLRHSTLDAHHQVVGNIQDVDTVKPYNMLSHLENNSNVTKQTAVAIADMG---VYDTR--- 317
                                                  ||        |:|..|   :||:|
Mosquito   244 --------------------------------------NS--------AMAAAGGSMIYDSRSSS 262

  Fly   318 -----------PPRPNSIELNRSYQ--SEQIDGSTYEQLPPQMGNQYAATFGNGMGGPQQMHMQH 369
                       ..|||||||.||||  :|.:||..|  .||..        |.|.|..|||.:|.
Mosquito   263 AMGGSSSGGGGAARPNSIELRRSYQQPNEMVDGGGY--APPSP--------GGGGGYHQQMAVQM 317

  Fly   370 QQMYDAGMYQSHALYGQ---------TGQGVMSPEPIYGPGTPSRNKPRPSQPPPAPPSNGSGGG 425
            ||  ..|:||...:|.|         .|...||.|.:|.||||||:|.|||||||||||:|||||
Mosquito   318 QQ--GGGVYQQQPIYDQYGNPSAMYGAGTNQMSQESLYAPGTPSRSKSRPSQPPPAPPSSGSGGG 380

  Fly   426 TPTASNANTPTRGRSMSTSRDALPPPPPVPDVI-SPMSGM-NGVNSGHMAAKLLGRANSSSGAGS 488
            ||.|||||||||.||:||.||.||||||:|:.: ||..|: ||..|  :||||| ...|.|.|||
Mosquito   381 TPNASNANTPTRSRSLSTGRDNLPPPPPIPEGLQSPPHGLSNGGTS--VAAKLL-LNRSGSRAGS 442

  Fly   489 P----------------------------------NSVQNANDMVMTQLSNTFHSIGMTGNQLN- 518
            |                                  .|:.:.|.:.:.||:...:::.....|||
Mosquito   443 PQLGMTGGPQQQQQQHQQQQQQQQPQHHHQQQVVVQSMMDQNQIALAQLNQQINNLNNLNMQLNQ 507

  Fly   519 -SLSDLPPPPPVPDQHSPKMSPPNAAPPPPPPPPPVEEGMGSGNQHTLRPHQILPKSLANGEMQQ 582
             |::|||||||:|:|.|||.||||.||||||||||:.:|       .|.|.:   ..:|||::..
Mosquito   508 MSMNDLPPPPPIPEQLSPKQSPPNVAPPPPPPPPPMLDG-------PLSPSK---APVANGDLYN 562

  Fly   583 PGQQNGVPHIVAPK----KMLPP-----FHDPRNDLMKAIRDGITLRKVEKS--EQKEIERNAAP 636
                       .||    |.:||     :.|||:||||||||||.||||||.  |.||.:||...
Mosquito   563 -----------MPKMHQLKKIPPQEKITYDDPRSDLMKAIRDGIKLRKVEKQNHEAKENDRNKGL 616

  Fly   637 LDVASILARRVAIELSESEDSDSEDDSEGWMEPNETSA 674
            .||||||||||||||||||.|:|:||||||.|.|||||
Mosquito   617 HDVASILARRVAIELSESESSESDDDSEGWQETNETSA 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCAR	NP_001260368.1	WH2	599..>650	CDD:425359	37/57 (65%)
SCAR	XP_061517179.1	None