Protein Alignment Tmem214 and Tmem214

DIOPT Version :10

• Sequence 1: NP_788023.1
• Gene: Tmem214 / 34514
• FlyBaseID: FBgn0053129
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_653108.2
• Gene: Tmem214 / 68796
• MGIID: 1916046
• Length: 687
• Species: Mus musculus
• Alignment Length: 580
• Identity: 146/580 - (25%)
• Similarity: 241/580 - (41%)
• Gaps: 68/580 - (11%)

  Fly     5 WEVVSKSRKQ-KNLDKKVSAHNEQKRIAAQ---LPKLEELLPTQR----YRNLFGSSNNNNSKSH 61
            ||||.:.|:. .:...:.......:|...:   :.|.:...|.|.    |...|.......:|..
Mouse    11 WEVVKRGRRPGASSGGRGGGGGSDRRALGEANGVLKYDLSSPIQTTSTLYERGFEKIMKRQNKEQ 75

  Fly    62 SPAKSSSSASSSSKANKSPVKKHTAKNASTQKRTTSAAASKPKTLELALRNITRDDFAA---QLE 123
            .|   ..:|.|....||...||.||..:..||:      ...:.||.||:.:   |.||   :|:
Mouse    76 VP---PPAAESKKPINKKQPKKVTAVPSQNQKQ------GPFRRLEDALKAL---DVAALQKELD 128

  Fly   124 QVKLSCPGSELRWLSHIALYFNEALSYD-CDPIFSGRSAQYPSNLASASLKYSIVEFLGSVGEQN 187
            :.:....|:...||..:|.|.|..|... .:|..|.....||.:|.|..|: .|:..|.:....:
Mouse   129 KSQSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELR-GIIRGLLTKAAGS 192

  Fly   188 LEYFFYSLLDSMSTDLNN--NQTVAGYKLILQLIGQNWPNICSRNLAKTALLRNSYQNRSNICLS 250
            :|.||...|.:|..:|:.  .:::.||::.:|.:.|:.|.|.:.||.|...|..|:|:|...||:
Mouse   193 VELFFDHCLFTMLQELDKTPGESLHGYRICIQAVLQDKPKIVTSNLDKFLELLRSHQSRPAKCLT 257

  Fly   251 ILWAIGQGGYQSLNEGVRVWQNLMLPNLELKQYTKFVVEYMERALSAAAVRKTADPLQINQQEFF 315
            |:||:||.|:.:|.||::||..:|||.|.:|..:.|.:.|::|.| ......|.....|..::||
Mouse   258 IMWALGQAGFTNLTEGLKVWLGIMLPVLGIKALSPFAIAYLDRLL-LMHPNLTKGFGMIGPKDFF 321

  Fly   316 ATYNALNAPYNHLPKEWQQSL-KRSARLLLQHYINSPVRHANIFLTLFREISAGSKQTNEIEGCI 379
            ...:....|.|.|....|:.| :...||.:..:...|....:.:...|.     |:.|......:
Mouse   322 PLLDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFL-----SRATPSCPAAM 381

  Fly   380 SCLLSSGRDDCL-------RVWRMNYKKQQLPSLLLLKAINDNWTTSTHELATSTVYHSFLQDVA 437
            ...|.:....||       .|||..|.|....|.|||:.:..:|.....:...|  ....:|.:.
Mouse   382 KKELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLKSWEHIPKKARKS--LQETIQSLK 444

  Fly   438 NLNEEL--QGSKRNEGHL--DDLKEVLLSVQEKSSAQQKKNKQKAAAEKKKCGCCKWTLGSIFII 498
            ..|:||  :||..:|..|  |...:.||              |:|...:.     .|....:.::
Mouse   445 VTNQELLKKGSGGSEHVLTCDTACKGLL--------------QRARGPRP-----PWARLFLLLL 490

  Fly   499 ALIAGALYYDTEVNGKGVFEKSATGKVLKNAGVLPHVQKSWYTVMGAGARGYKWAEVNVP 558
            ....|.|.:|...|..  .:.|.||::|:::|:||..|:....:.....:.|.|.:..:|
Mouse   491 VFAVGFLCHDLRSNSS--LQASLTGRLLRSSGLLPVGQQVCARLSSYSLQSYNWLQETLP 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmem214	NP_788023.1	TMEM214	2..668	CDD:462966	146/580 (25%)
Tmem214	NP_653108.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		6/27 (22%)
		TMEM214	8..681	CDD:462966	146/580 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	70..108		10/37 (27%)