Protein Alignment Tmem214 and Tmem214

DIOPT Version :10

• Sequence 1: NP_788023.1
• Gene: Tmem214 / 34514
• FlyBaseID: FBgn0053129
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001014217.2
• Gene: Tmem214 / 362711
• RGDID: 1311324
• Length: 685
• Species: Rattus norvegicus
• Alignment Length: 712
• Identity: 167/712 - (23%)
• Similarity: 284/712 - (39%)
• Gaps: 125/712 - (17%)

  Fly     5 WEVVSKSRKQKNLDKKVSAHNEQKRI--AAQLPKLEELLPTQ----RYRNLFGSSNNNNSKSHSP 63
            ||||.:||:............:::.:  |..:.|.:...|.|    .|...|.......:|...|
  Rat    11 WEVVKRSRRPGASSGGRGGGGDRRALGEANGVWKYDLSSPIQPTSTLYERGFEKIMKRQNKEQVP 75

  Fly    64 AKSSSSASSSSKANKSPVKKHTAKNASTQKRTTSAAASKPKTLELALRNITRDDFAA---QLEQV 125
               ..:|.|....||...||.||..:..||:      ...::||.||:.:   |.||   :|::.
  Rat    76 ---PPAAESKKPVNKKQPKKVTAVASQNQKQ------GPFRSLEDALKAL---DVAALQKELDKS 128

  Fly   126 KLSCPGSELRWLSHIALYFNEALSYD-CDPIFSGRSAQYPSNLASASLKYSIVEFLGSVGEQNLE 189
            :....|:...||..:|.|.|..|... .:|..|.....||.:|.|..|: .|:..|.:....::|
  Rat   129 QSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELR-GIIRGLLTKAAGSVE 192

  Fly   190 YFFYSLLDSMSTDLNN--NQTVAGYKLILQLIGQNWPNICSRNLAKTALLRNSYQNRSNICLSIL 252
            .||...|.:|..:|:.  .:::.||::.:|.|.|:.|.|.:.||.|...|..|:|:|...||:|:
  Rat   193 LFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIVTSNLDKFLELLRSHQSRPAKCLTIM 257

  Fly   253 WAIGQGGYQSLNEGVRVWQNLMLPNLELKQYTKFVVEYMERALSAAAVRKTADPLQINQQEFFAT 317
            ||:||.|:.:|.||::||..:|||.|.:|..:.|.:.|::|.| ......|.....|..::||..
  Rat   258 WALGQAGFTNLTEGLKVWLGIMLPVLGIKSLSPFAIAYLDRLL-LMYPNLTKGFGMIGPKDFFPL 321

  Fly   318 YNALNAPYNHLPKEWQQSL-KRSARLLLQHYINSPVRHANIFLTLFREISAGSKQTNEIEGCISC 381
            .:....|.|.|....|:.| :...||.:..:...|....:.:...|.     |:.|......:..
  Rat   322 LDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFL-----SRATPSCPAAMKK 381

  Fly   382 LLSSGRDDCL-------RVWRMNYKKQQLPSLLLLKAINDNW---TTSTHELATSTVYHSFLQDV 436
            .|.:....||       .|||..|.|....|.|||:.:..:|   .....:....|:     |..
  Rat   382 ELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLTSWEQIPKKARKCLQETI-----QSF 441

  Fly   437 ANLNEEL--QGSKRNEGHLDDLKEVLLSVQEKSSAQQKKNKQKAAAEKKKCGCCKWTLGSIFIIA 499
            ...|:||  :||..|| |:     |......|...||.:..:.           .|....:.::.
  Rat   442 TLTNQELLKKGSGSNE-HV-----VTCDTACKGLLQQARGPRP-----------PWARLLLLLLV 489

  Fly   500 LIAGALYYDTEVNGKGVFEKSATGKVLKNAGVLPHVQKSWYTVMGAGARGYKWAEVNVPPYAEPV 564
            ...|.|.:|  :.....|:.|.||::|:::|:||..|:....:.....:.|.|.:..:|
  Rat   490 FAVGFLCHD--LRSHSSFQASLTGRLLQSSGLLPVAQQVCAKLYSYSLQSYNWLQETLP------ 546

  Fly   565 IKTTCDLWKLARNAACNAY---------QNGKGYFGAKWPVVAKFIDQYVPNSSGKIEAFAAGVS 620
                          ||.:|         |....|..|.:..::.:...|:        ||
  Rat   547 --------------ACGSYLLAVVQPSLQLAWTYIYATFSFLSAYCASYL--------AF----- 584

  Fly   621 DLAASSYEKAAALIKEKVLVGRLSPENINQALNQTRNAALEYYN-----QFHKKVDAYAKLK 677
                  :..:.|.:.::|.:    ||.::|..:..:...|.:|:     .:|..:.|.|:::
  Rat   585 ------FSDSLAGVLQRVQL----PEALHQLFHSLKELLLLFYHSVLLPMWHLLLAALAQVQ 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmem214	NP_788023.1	TMEM214	2..668	CDD:462966	164/701 (23%)
Tmem214	NP_001014217.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		6/24 (25%)
		TMEM214	8..679	CDD:462966	165/706 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	66..104		11/37 (30%)