Protein Alignment Tmem214 and Tmem214

DIOPT Version :10

• Sequence 1: NP_788023.1
• Gene: Tmem214 / 34514
• FlyBaseID: FBgn0053129
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_318929.5
• Gene: Tmem214 / 1279237
• VectorBaseID: AGAMI1_003371
• Length: 697
• Species: Anopheles gambiae
• Alignment Length: 713
• Identity: 237/713 - (33%)
• Similarity: 360/713 - (50%)
• Gaps: 52/713 - (7%)

  Fly     1 MSEQWEVV---SKSRKQKNLDKKVSAHNEQKRIAAQLPKLEELLPTQRYRNLFGSSNNN-NSKSH 61
            |:..|.||   .|||||...|||..:.|..:    ..||:|:::......:|:....:: .:|.:
Mosquito     1 MAADWAVVGKQKKSRKQTGGDKKTQSQNGSE----SAPKIEDMVDMDEICSLYSDVKDDVFAKFN 61

  Fly    62 SPAKSSSSASSSSKANKSPVK-KHTA-------------KNASTQKRTTSAAASKPK----TLEL 108
            ....:::.|.:..|...:||. |.||             .|.:.|:|...:.|:..|    :|:.
Mosquito    62 GLKDANAGAKADPKKTLAPVNGKRTATPVRDQALQQGGGSNKNNQQREPESGATPAKQTYRSLDA 126

  Fly   109 ALRNITRDDFAAQLEQVKLSCPGSELRWLSHIALYFNEALSYD---CDPIFSGRSAQYPSNLASA 170
            |||.|:..|..:||..|.:|...:.|..|..:....|:.|..|   .||::|.:...||......
Mosquito   127 ALRAISAPDLHSQLAAVNVSFKDNHLMLLKALTGILNDKLRVDDAAADPLYSSKPTTYPYKTMPT 191

  Fly   171 SLKYSIVEFLGSVGEQNLEYFFYSLLDSMSTDLNNNQTVAGYKLILQLIGQNWPNICSRNLAKTA 235
            :|:..|.|.:|...|:|::||:...|.::::|||......|:|:|||.|..::|:.|..|||:.|
Mosquito   192 ALRTVIDECIGKANEENVKYFYDLTLSNLASDLNKGLPHLGHKVILQAIAMHYPSACVNNLARNA 256

  Fly   236 LLRNSYQNRSNICLSILWAIGQGGYQSLNEGVRVWQNLMLPNLELKQYTKFVVEYMERALSAAAV 300
            :||||||||.||.||:|||:|||||..|:.|::|||::|:|.:|||.|.:|..:|:.|.|..
Mosquito   257 ILRNSYQNRHNIGLSLLWALGQGGYNDLDVGLKVWQDIMVPVMELKNYNRFTSDYVVRILRL--- 318

  Fly   301 RKTADPLQINQQEFFATYNALNAPYNHLPKEWQQSLKRSARLLLQHYINSPVRHANIFLTLFREI 365
             ..|..|.:...||....::|...    ||..:: |..:|:||::.|:.|..:.:..|..||:.:
Mosquito   319 -HRAHRLTLGGSEFLTILSSLTTQ----PKACRE-LDEAAQLLVERYVFSAPKASATFTMLFKNV 377

  Fly   366 SAGSKQTNEIEGCISCLLSSGRDDCLRVWRMNYKKQQLPSLLLLKAINDNWTTSTHELATSTVYH 430
            |..::......|...|||..  .:...||...|:.....||.:|..:|.:...:..:|.....:.
Mosquito   378 SFITRPEMIYYGLALCLLED--PESAAVWLGLYRSNVETSLAILSYLNTSSQKNCSKLLGEDHFI 440

  Fly   431 SFLQDVANLNEELQGSKRNEGHLDDLKEVLLSVQEKSSAQQKKNKQKAAAEKKKCGCCKWTLGSI 495
            .||.||..||||||.||:....|:.:..:|..||.||..:|.......::.......|.:.|.:.
Mosquito   441 RFLSDVEKLNEELQQSKKKIEGLESVTSILKEVQGKSKKKQSSKVNSKSSSSVTSVLCSFLLATF 505

  Fly   496 FIIALIAGALYYDTEVNGKGVFEKSATGKVLKNAGVLPHVQKSWYTVMGAGARGYKWAEVNVPPY 560
            .:..:....:.|||...| |.||.|.||:.||.||:||.||.:|...|...||||||||.|||.|
Mosquito   506 LLFGVTGALIGYDTYRAG-GKFEASFTGQTLKQAGLLPAVQDAWTCTMKYSARGYKWAETNVPVY 569

  Fly   561 AE-------PVIKTTCDLWKLARNAACNAYQNGKGYFGAKWPVVAKFIDQYVPNSSGKIE----A 614
            .:       |.::.:.|..|:..|.....:.|.|.....|.||||.||:||.|....||.    |
Mosquito   570 YQATSKALGPYVEFSIDFGKVLWNGTKKGFANMKLLAEQKLPVVADFIEQYAPGLPKKIGDASCA 634

  Fly   615 FAAGVSDLAASSYEKAAALIKEKVLVGRLSPENINQALNQTRNAALEYYNQFHKKVDAYAKLK 677
            |...||..|:::|:......|.:|.||:||.|::.:|.|.|:.||.:||:.|:.:||.|||||
Mosquito   635 FCDTVSTFASNAYKHTFEFFKTQVFVGKLSMESLGKAFNSTQQAAAQYYSWFNDQVDFYAKLK 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmem214	NP_788023.1	TMEM214	2..668	CDD:462966	229/701 (33%)
Tmem214	XP_318929.5	None