Protein Alignment CG7309 and SLC13A3

DIOPT Version :10

• Sequence 1: NP_609468.4
• Gene: CG7309 / 34509
• FlyBaseID: FBgn0032314
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_073740.2
• Gene: SLC13A3 / 64849
• HGNCID: 14430
• Length: 602
• Species: Homo sapiens
• Alignment Length: 561
• Identity: 118/561 - (21%)
• Similarity: 220/561 - (39%)
• Gaps: 92/561 - (16%)

  Fly    20 RRLFCKYHYKGVLLLFIPILLAPILIGTPVLICRFIYLTLCLYLIYILNLMARGAAAFIYMVFIP 84
            |||        ::|||.|:.|.|::...|....|.:::.|.:.:.:....:.....|.:.:|..|
Human    15 RRL--------LVLLFTPLALLPVVFALPPKEGRCLFVILLMAVYWCTEALPLSVTALLPIVLFP 71

  Fly    85 VAGIASSKEISVSYYTDLIFFVYSAIFMGIMMDSSKLSDRLAFIVISLVGGSLKFLQIFLTIAAA 149
            ..||..|.::...|:.|..|...|.:.|...::...|..|:|..::.|||.....|.:.:.:..:
Human    72 FMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTS 136

  Fly   150 IVSILVNPTISAAFWMKVSQAVMVEY---------------DNGGLIKLNS-EEKPYEI------ 192
            .:|:.::.|.|.|..:.::.|::...               :|...::.|. ...|.|:
Human   137 FLSMWLSNTASTAMMLPIANAILKSLFGQKEVRKDPSQESEENTAAVRRNGLHTVPTEMQFLAST 201

  Fly   193 GSKPYPTRPVI--------------------GIYLTCCYAASL--AASLSPIVNPNGVI---SDG 232
            .:|.:|....:                    |..::..|:||:  .|:|:... ||.::   ...
Human   202 EAKDHPGETEVPLDLPADSRKEDEYRRNIWKGFLISIPYSASIGGTATLTGTA-PNLILLGQLKS 265

  Fly   233 FGGSLTVLEIG--MLMAGPALMGLVVMIFWLQVLFL--GLLGGSVKRDLAEM-AGAKAGFKQTAS 292
            |.....|:..|  .:.|.| ||.|.::..||.:.||  ||.....:::.:|: ..|:...:....
Human   266 FFPQCDVVNFGSWFIFAFP-LMLLFLLAGWLWISFLYGGLSFRGWRKNKSEIRTNAEDRARAVIR 329

  Fly   293 ERKQALGPWGIYPILALSLILLMFLLVATRKPRIFTGWDSINYKAESGLSVAGIGMSILFFAIPA 357
            |..|.|||..........|..:..:|:.||.|:...||.|:........:|.|:.:..:.|..|:
Human   330 EEYQNLGPIKFAEQAVFILFCMFAILLFTRDPKFIPGWASLFNPGFLSDAVTGVAIVTILFFFPS 394

  Fly   358 NYIFCRYYV-CRQPEKEGPANSLLGWKAVNNNTPWAEIFMLGAAFSFSYSSAVCGLNTYLADSMN 421
            .....:::. .:.|..|  ...||.||......||..|.:||..|:.:......||:.::...::
Human   395 QRPSLKWWFDFKAPNTE--TEPLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLH 457

  Fly   422 S-DNKGFNMKSFICGALLGTLWTTLSPATTV-------AKLALPTMV---------TAGNSFSLP 469
            . :|....:...:...::.......|...|:       |:||:...|         |.|.||:
Human   458 PLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHPLYLMIPGTVGCSFA-- 520

  Fly   470 FATALHNQFLLPVSSPANTIVAGWGNVRPFQFLLGGSILTL 510
                    |:||||:|.|:|....|::.....:..|.::.|
Human   521 --------FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNL 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7309	NP_609468.4	CitT	108..523	CDD:440239	97/473 (21%)
SLC13A3	NP_073740.2	CitMHS	<11..162	CDD:460985	35/154 (23%)
		CitT	94..566	CDD:440239	97/474 (20%)