Protein Alignment CG7309 and SLC13A4

DIOPT Version :10

• Sequence 1: NP_609468.4
• Gene: CG7309 / 34509
• FlyBaseID: FBgn0032314
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_001305121.1
• Gene: SLC13A4 / 26266
• HGNCID: 15827
• Length: 627
• Species: Homo sapiens
• Alignment Length: 604
• Identity: 125/604 - (20%)
• Similarity: 219/604 - (36%)
• Gaps: 176/604 - (29%)

  Fly    29 KGVLLLFIPILLAPILIGTPVL------ICRFIYLTLCLYLIYILNLMARGAAAFIYMVFIPVAG 87
            |.:|::.:|:||.|:    |||      .|.::.:...:|  ::...:..||||.:.....|..|
Human    12 KLLLVVCVPLLLLPL----PVLHPSSEASCAYVLIVTAVY--WVSEAVPLGAAALVPAFLYPFFG 70

  Fly    88 IASSKEISVSYYTDLIFFVYSAIFMGIMMDSSKLSDRLAFIVISLVGGSLKFLQIFLTIAAAIVS 152
            :..|.|::..|:.:....:...|.:...::...|..|:|..::.:.|.....|.:.......::|
Human    71 VLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCCTTLLS 135

  Fly   153 ILVNPTISAAFWMKVSQAV---MVEYDNGGLIKLNS---EEKPYEI------------------- 192
            :.::.|.:.|..|.:.:||   :|..::..|:..||   |.:|..:
Human   136 MWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNSQPSLELIFVNEDRS 200

  Fly   193 ------------------------------GSKPYPT--RPVIGIYLT----------------- 208
                                          |.|.:|:  :|.:   ||
Human   201 NADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQV---LTPSPRKQKLNRKYRSHHD 262

  Fly   209 --CCYAASLAASLSPIVNPNGVISDGFGGSLTVLE---------------IGMLMAGP-ALMGLV 255
              .|...||:.|.|..:.....|. |...||..||               ...|.:.| :|:.||
Human   263 QMICKCLSLSISYSATIGGLTTII-GTSTSLIFLEHFNNQYPAAEVVNFGTWFLFSFPISLIMLV 326

  Fly   256 VMIFWLQVLFLGLLGGSVKRDLAEMAGAKAGFKQTAS------------------ERKQALGPWG 302
            |..||:..||||                 ..||:|.|                  |..:.||...
Human   327 VSWFWMHWLFLG-----------------CNFKETCSLSKKKKTKREQLSEKRIQEEYEKLGDIS 374

  Fly   303 IYPILALS-LILLMFLLVATRKPRIFTGWDSI----NYKAESGLSVAGIGMSILFFAIPANYIFC 362
             ||.:... ..:||.:|..||:|....||||.    .|:.::.:||.   :..|.|.|||.
Human   375 -YPEMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKGYRTDATVSVF---LGFLLFLIPAK---- 431

  Fly   363 RYYVC--RQPEKEGPANSL-----LGWKAVNNNTPWAEIFMLGAAFSFSYSSAVCGLNTYLADSM 420
              ..|  ::.:.|...:||     :.||......||..:.::|..::.:..|...||:|::.:.|
Human   432 --KPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASGSKSSGLSTWIGNQM 494

  Fly   421 NSDNKGFNMKSFICGALLGTLWTTL--SPATTVAKLALPTMVTAGNSFS-------LPFATALHN 476
            .|.:........:...:|.::.|..  :|||..  :.||.:.:...:..       :|....:..
Human   495 LSLSSLPPWAVTLLACILVSIVTEFVSNPATIT--IFLPILCSLSETLHINPLYTLIPVTMCISF 557

  Fly   477 QFLLPVSSPANTIVAGWGN 495
            ..:|||.:|.|.||..:|:
Human   558 AVMLPVGNPPNAIVFSYGH 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7309	NP_609468.4	CitT	108..523	CDD:440239	105/519 (20%)
SLC13A4	NP_001305121.1	CitT	90..604	CDD:440239	105/520 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..253		6/37 (16%)