DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14070 and ERV29

DIOPT Version :9

Sequence 1:	NP_001285818.1	Gene:	CG14070 / 34508	FlyBaseID:	FBgn0032313	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_011800.3	Gene:	ERV29 / 853201	SGDID:	S000003516	Length:	310	Species:	Saccharomyces cerevisiae

Alignment Length:	239	Identity:	58/239 - (24%)
Similarity:	108/239 - (45%)	Gaps:	55/239 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YFMEVLYSVVNTPLVGRERAIVMDVNECFGHFYTCFDVLLTIGAIFLILGTRKEASGVTLLLIGR 73
            ||..|::.||.|                         |.:.|||..|:|  ||:.:..|.:|...
Yeast   108 YFFVVVFLVVVT-------------------------VSMLIGASLLVL--RKQTNYATGVLCAC 145

  Fly    74 VIHR-LFFSIWTMFFYFLFNDSLDVGSLLLLMAAKI-----------NLRDQMDWFQSKYHILLL 126
            ||.: |.:.::|...:.|.|.|: :|.||:..:..|           .|..:.|  ::|.: ||.
Yeast   146 VISQALVYGLFTGSSFVLRNFSV-IGGLLIAFSDSIVQNKTTFGMLPELNSKND--KAKGY-LLF 206

  Fly   127 GGRLCLSSLYIIWIDEGLETLFSIV--SFGLLVFIWLGFHCKLFAYLTVIALLYHDVFSNHWSML 189
            .||:.:..::|.:...  ::.|::|  ..|.:.|. :|:..|..:.:..:.|.::::..|::
Yeast   207 AGRILIVLMFIAFTFS--KSWFTVVLTIIGTICFA-IGYKTKFASIMLGLILTFYNITLNNY--- 265

  Fly   190 WGWNDT---LLSIQYFSLLFCKIGGFLMLSELGGGRWSVDGYRK 230
            |.:|:|   .|..:::..|.. |||.|:::..|.|..|||..:|
Yeast   266 WFYNNTKRDFLKYEFYQNLSI-IGGLLLVTNTGAGELSVDEKKK 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14070	NP_001285818.1	DoxX	<46..231	CDD:304411	52/202 (26%)
ERV29	NP_011800.3	DoxX	48..310	CDD:419711	58/239 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2259
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.860