Protein Alignment Stam and HSE1

DIOPT Version :10

• Sequence 1: NP_477448.1
• Gene: Stam / 34505
• FlyBaseID: FBgn0027363
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_011861.1
• Gene: HSE1 / 856387
• SGDID: S000000994
• Length: 452
• Species: Saccharomyces cerevisiae
• Alignment Length: 510
• Identity: 135/510 - (26%)
• Similarity: 222/510 - (43%)
• Gaps: 111/510 - (21%)

  Fly    16 KATSETNTNDNWSLILDVCDKVTTNPR-LAKDCLKAVMRRMGHTDPHVVMQAITLLDALSNNCGK 79
            |||.....:|||..||||||.|..:|. ..::.:..:.:|:...|.:|:::.::|..:|:.|||.
Yeast    14 KATDPKLRSDNWQYILDVCDLVKEDPEDNGQEVMSLIEKRLEQQDANVILRTLSLTVSLAENCGS 78

  Fly    80 PLHLEVASRDFETEFRRLLAKAQPKVSLK--MRQVLKNWAENDYKNDRELDLIPALYAKLRQEGY 142
            .|..|::|::|.:....|:......::||  :..|:|..::: :|:|..|..:..||.|:::
Yeast    79 RLRQEISSKNFTSLLYALIESHSVHITLKKAVTDVVKQLSDS-FKDDPSLRAMGDLYDKIKR--- 139

  Fly   143 DFKNLGDKTSKTVAEKAAALPKDPNV-----VSSQ---QEEDDIAKAIELSLKENKGSPKTGSVA 199
                           ||..|.: |||     :|:|   .:::::.||:::||.|.:   |...:.
Yeast   140 ---------------KAPYLVQ-PNVPEKHNMSTQADNSDDEELQKALKMSLFEYE---KQKKLQ 185

  Fly   200 STGTASAYPSLYPSFAGTGSSAPSAEASSAPAPE-PRKVRALYDFEAAEENELTFFAGEIIHVLD 263
            .....||  .:.|...........|.|...||.. .|:||||||....|.:||:|..|::|.||:
Yeast   186 EQEKESA--EVLPQQQQQHQQQNQAPAHKIPAQTVVRRVRALYDLTTNEPDELSFRKGDVITVLE 248

  Fly   264 DSDPNWWKGYNQRGEGLFPSNFVTADLSVDPERLDINQQHKSAAAAGQRELDSAAALQQKTEAAA 328
            ....:||||..:...|:||.|:||.  .|:|.:.:|.::...          .|....|||
Yeast   249 QVYRDWWKGALRGNMGIFPLNYVTP--IVEPSKEEIEKEKNK----------EAIVFSQKT---- 297

  Fly   329 AAAAAQPVEIDESKIDRLLHLLHEANPEDPSQDSDEMLQ------LEQEVHQMGPLIDAELERVD 387
                         .||:|.:.|:.|:   .:.:|:|:||      :...|..:.|.:...|.:..
Yeast   298 -------------TIDQLHNSLNAAS---KTGNSNEVLQDPHIGDMYGSVTPLRPQVTRMLGKYA 346

  Fly   388 RKHAQLTQLSSDLVDAINLYHTLMRDDRAAAGHFAAAAGGFMPGLAGFPGAALYGAPGYPAAGGF 452
            ::...:..|...|.:|...|:.||  ||||..|.:...          ||.|||        .|.
Yeast   347 KEKEDMLSLRQVLANAERSYNQLM--DRAANAHISPPV----------PGPALY--------AGM 391

  Fly   453 PPAQNYPGM-------HSMPYGPVPN-----PPTSAPSQAP--GAPGGY--LGQP 491
            ..|.|.|.|       .|..|.|.|:     .||::.:..|  |...||  :.||
Yeast   392 THANNTPVMPPQRQSYQSNEYSPYPSNLPIQHPTNSANNTPQYGYDLGYSVVSQP 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stam	NP_477448.1	VHS_STAM	10..141	CDD:340770	37/127 (29%)
		SH3_STAM	235..288	CDD:212754	24/52 (46%)
		GAT_STAM	337..413	CDD:410593	18/81 (22%)
		PHA03247	<436..526	CDD:223021	22/72 (31%)
HSE1	NP_011861.1	VHS_HSE1	8..140	CDD:340775	37/144 (26%)
		SH3_GRB2_like_C	221..273	CDD:212739	23/51 (45%)
		GAT_Hse1	290..374	CDD:410591	24/105 (23%)