Protein Alignment Stam and BEM1

DIOPT Version :10

• Sequence 1: NP_477448.1
• Gene: Stam / 34505
• FlyBaseID: FBgn0027363
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_009759.3
• Gene: BEM1 / 852499
• SGDID: S000000404
• Length: 551
• Species: Saccharomyces cerevisiae
• Alignment Length: 293
• Identity: 71/293 - (24%)
• Similarity: 114/293 - (38%)
• Gaps: 70/293 - (23%)

  Fly   183 ELSLKENK-----GSPK---TGSVASTGTASAYPSLY-PSFAGTGSSAPSAEASSAPAPEPRKVR 238
            |||..|.:     |..|   ..|..|||.....|..| ..|..|..|:.:...||:     |||.
Yeast    90 ELSFMEGEFFYVSGDEKDWYKASNPSTGKEGVVPKTYFEVFDRTKPSSVNGSNSSS-----RKVT 149

  Fly   239 ------------ALYDFEAAEENELTFFAGEIIHVLDDSDPNWW--KGYNQ-RGEGLFPSNFVTA 288
                        .||||:|.:.:|||.:.||.:.:....:..|:  |...: .|.||.|..||:.
Yeast   150 NDSLNMGSLYAIVLYDFKAEKADELTTYVGENLFICAHHNCEWFIAKPIGRLGGPGLVPVGFVSI 214

  Fly   289 -----------DLSVDPERLDIN--QQHKSAAAAGQRELDSAAALQQKTEAAAAAAAAQPVEIDE 340
                       |:..|.:.:::.  |:.||..|..:....|..:::|:.:        |.:...:
Yeast   215 IDIATGYATGNDVIEDIKSVNLPTVQEWKSNIARYKASNISLGSVEQQQQ--------QSITKPQ 271

  Fly   341 SKIDRLL--HLLHEANPEDPSQDSDEMLQLEQEVHQMGPLIDAEL-----ERVDRKHAQLTQLSS 398
            :|..:|:  .||.:|        |.|...||.|.:..  |:..||     .::.|.:.....|..
Yeast   272 NKSAKLVDGELLVKA--------SVESFGLEDEKYWF--LVCCELSNGKTRQLKRYYQDFYDLQV 326

  Fly   399 DLVDAINLYHTLMRDDRAAAGHFAAAAGGFMPG 431
            .|:||.......:||   |.|.::.....::||
Yeast   327 QLLDAFPAEAGKLRD---AGGQWSKRIMPYIPG 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stam	NP_477448.1	VHS_STAM	10..141	CDD:340770
		SH3_STAM	235..288	CDD:212754	21/67 (31%)
		GAT_STAM	337..413	CDD:410593	18/82 (22%)
		PHA03247	<436..526	CDD:223021
BEM1	NP_009759.3	SH3_Bem1p_1	76..127	CDD:212811	11/36 (31%)
		SH3_Bem1p_2	159..214	CDD:212812	18/54 (33%)
		PX_Bem1p	284..400	CDD:132800	20/86 (23%)
		PB1	478..549	CDD:214770