DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Stam and AT2G38410

DIOPT Version :9

Sequence 1:	NP_477448.1	Gene:	Stam / 34505	FlyBaseID:	FBgn0027363	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_181375.1	Gene:	AT2G38410 / 818422	AraportID:	AT2G38410	Length:	671	Species:	Arabidopsis thaliana

Alignment Length:	725	Identity:	162/725 - (22%)
Similarity:	238/725 - (32%)	Gaps:	167/725 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VEKATSETNTNDNWSLILDVCDKVTTNPRLAKDCLKAVMRRMGHTDPHVVMQAITLLDALSNNCG 78
            |:||||:.....:|:..:::||.|.:....|||.:|||.:|:.|....|.:.|:|||:.|..|||
plant    12 VDKATSDLLLGPDWTTNMEICDSVNSLHWQAKDVVKAVKKRLQHKSSRVQLLALTLLETLVKNCG 76

  Fly    79 KPLHLEVASRDFETEFRRLL-AKAQPKVSLKMRQVLKNWAENDYKNDRELDLIPALYAKLRQEGY 142
            ..||.:||.::...|..::: .||..:|..|:..::.:|.:.....:.:.......|.:||:.|.
plant    77 DYLHHQVAEKNILGEMVKIVKKKADMQVRDKILVMVDSWQQAFGGPEGKYPQYYWAYDELRRSGV 141

  Fly   143 DFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGS---PKTG---SVAST 201
            :|.......|..:....:..|                      |::.:|.   |..|   ..|..
plant   142 EFPRRSPDASPIITPPVSHPP----------------------LRQPQGGYGVPPAGYGVHQAGY 184

  Fly   202 GTASA----------YPSLYPSFAGTGSSAPSAEASSAPAPEPRKVRALYDFEAAEENELTFFAG 256
            |...|          .|.........|...||..:.........:|..|.........::....|
plant   185 GVPQAGYGIPQAGYGVPQAGYGIPQVGYGMPSGSSRRLDEAMATEVEGLSLSSIESMRDVMDLLG 249

  Fly   257 EIIHVLDDSDPNWWKGYNQRGEGLFPSNFVTADLSVDPERLDINQQH--KSAAAAGQREL----- 314
            :::..:|.||....|            :.|..||   .||...||:.  :...:.|..||
plant   250 DMLQAVDPSDREAVK------------DEVIVDL---VERCRSNQKKLMQMLTSTGDDELLGRGL 299

  Fly   315 ---DSAAALQQKTEAAAAA------AAAQPVEIDESKIDRLLHLLHEANPEDPSQDSDEMLQLEQ 370
               ||...|..|.:|.|:.      |:..|:.:..||            |.|.|..|.|......
plant   300 DLNDSLQILLAKHDAIASGSPLPVQASGSPLSVQASK------------PADSSPKSSEAKDSSS 352

  Fly   371 EVHQMGPL----------IDAELERVDRKHAQLTQLSSDLVDAINLYHTLMRDDRAAAGHFAAAA 425
            ......|:          ||.|.|..:.:.|||.:..|....::....|.:....||:...|.|
plant   353 IAGSSSPIPATVSTGKSPIDEEYEEEEDEFAQLARRHSKPPASVTTDPTSLESHNAASNALALA- 416

  Fly   426 GGFMPGLAGFPGAALYGAPGYPAAGGFPPAQNYPGMHSMPYGPVPNPPTSAPSQAPGAPGGYLGQ 490
                             .|..|........|:...:.|:.......||  |||..|..|.
plant   417 -----------------LPDPPPPVNTTKEQDMIDLLSITLCTPSTPP--APSSQPSPPP----- 457

  Fly   491 PQGQVPLPYQNGHAAQMNSLPAHLTQPTGTAPMPQPIYTQPTPVTTQQQQQPLPQHP-------- 547
                                ||...|.|...|.|||.:........||||   ||.|
plant   458 --------------------PAGSDQNTHIYPQPQPRFDSYVAPWAQQQQ---PQQPQAQQGYSQ 499

  Fly   548 -QQPPQQQGQQPPQHPQNS------YHIDPQSQYAQ-VPPAVTQIQQPQQPPAPHAYMSPQHQQA 604
             ||..||||...|||.|..      ....||..|:| .|.|..|:|...:|..|:.|
plant   500 HQQHQQQQGYSQPQHSQQQQGYSQLQQPQPQQGYSQSQPQAQVQMQPSTRPQNPYEY-------- 556

  Fly   605 PPPQGYQPGPNLY---GPNGSPAVVNPQSYMSPQQQQQQHPPPHDQFSQLHQQMAAMSMAGGPPV 666
            |||.......|.|   ..|.|.:..:..:......||....|......|.....:...::.|...
plant   557 PPPPWASTSANAYYTPRANASASYTDTSALAGRSLQQSNSFPTRAGDPQATSTASNSGVSVGQKP 621

  Fly   667 GAPGYHMQND 676
            ..|.|.:..|
plant   622 FVPSYRLFED 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stam	NP_477448.1	VHS_STAM	10..154	CDD:239625	42/140 (30%)
		SH3_STAM	235..288	CDD:212754	8/52 (15%)
		GAT	340..412	CDD:281166	17/81 (21%)
AT2G38410	NP_181375.1	VHS	13..140	CDD:197630	38/126 (30%)
AT2G38410	NP_181375.1	GAT_GGA_like_plant	237..315	CDD:260089	19/92 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910