DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Stam and EndoA

DIOPT Version :9

Sequence 1:NP_477448.1 Gene:Stam / 34505 FlyBaseID:FBgn0027363 Length:689 Species:Drosophila melanogaster
Sequence 2:NP_001262717.1 Gene:EndoA / 42265 FlyBaseID:FBgn0038659 Length:369 Species:Drosophila melanogaster


Alignment Length:295 Identity:72/295 - (24%)
Similarity:117/295 - (39%) Gaps:61/295 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 KVTTNPR---LAKDCLKAVMRRMGHTDPHVVMQAI---------------TLLDALSNNCGKPLH 82
            |..|.|:   |..:|:....:::|. |..|..||:               :|.|.:..|..:|||
  Fly    82 KSNTYPQPEGLLAECMLTYGKKLGE-DNSVFAQALVEFGEALKQMADVKYSLDDNIKQNFLEPLH 145

  Fly    83 ----------------LEVASRDFETEFRRLLAK------AQPKV--SLKMRQV-LKNWAENDYK 122
                            |:....||:.: ||..||      |:.|.  ||::.|| :.|..|||.:
  Fly   146 HMQTKDLKEVMHHRKKLQGRRLDFDCK-RRRQAKDDEIRGAEDKFGESLQLAQVGMFNLLENDTE 209

  Fly   123 NDRELDLIPALYAKLRQEGYDFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKA-IELSL 186
            :..:|       ....:..|||.:......:.:.|   .|.:..:...|:...:.:.|. ::|:|
  Fly   210 HVSQL-------VTFAEALYDFHSQCADVLRGLQE---TLQEKRSEAESRPRNEFVPKTLLDLNL 264

  Fly   187 KENKGSPKTGSVASTGTASAYPSLYPSFAGTGSSAPSAEASSAPAPEPRKVRALYDFEAAEENEL 251
            ....|........|..::||.|...|..:...|.|.:.:....|.     .:||||||.....||
  Fly   265 DGGGGGLNEDGTPSHISSSASPLPSPMRSPAKSMAVTPQRQQQPC-----CQALYDFEPENPGEL 324

  Fly   252 TFFAGEIIHVLDDSDPNWWKGYNQRGEGLFPSNFV 286
            .|...:||.:|:..|.||::|......|.||.::|
  Fly   325 AFKENDIITLLNRVDDNWFEGAVNGRTGYFPQSYV 359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
StamNP_477448.1 VHS_STAM 10..154 CDD:239625 37/160 (23%)
SH3_STAM 235..288 CDD:212754 20/52 (38%)
GAT 340..412 CDD:281166
EndoANP_001262717.1 BAR_Endophilin_A 25..246 CDD:153276 39/175 (22%)
SH3_Endophilin_A 312..361 CDD:212737 20/48 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R571
SonicParanoid 00.000 Not matched by this tool.
11.030

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