DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Stam and drk

DIOPT Version :9

Sequence 1:	NP_477448.1	Gene:	Stam / 34505	FlyBaseID:	FBgn0027363	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster

Alignment Length:	233	Identity:	59/233 - (25%)
Similarity:	93/233 - (39%)	Gaps:	59/233 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 VASRDFETEFRRLLAKAQPKVSLKMRQVLK--------NW--AENDYKNDRELDLIPALYAKLRQ 139
            :|..||.       |.|..::|.:..|:||        ||  ||.|.|.    .|||:.|.:::.
  Fly     4 IAKHDFS-------ATADDELSFRKTQILKILNMEDDSNWYRAELDGKE----GLIPSNYIEMKN 57

  Fly   140 EGYDFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSPKTGSVASTGTA 204
            ..:.:    .:.::..|||         ::|::.|     .|..:.:.|:.....:.||......
  Fly    58 HDWYY----GRITRADAEK---------LLSNKHE-----GAFLIRISESSPGDFSLSVKCPDGV 104

  Fly   205 SAYPSLYPS-------------------FAGTGSSAPSAEASSAP-APEPRKVRALYDFEAAEEN 249
            ..:..|..:                   :..|.|.:.|.:..... .||...|:|||||...|..
  Fly   105 QHFKVLRDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEMLVQALYDFVPQESG 169

  Fly   250 ELTFFAGEIIHVLDDSDPNWWKGYNQRGEGLFPSNFVT 287
            ||.|..|::|.|.|.||.|||.|.....:|:||:.:||
  Fly   170 ELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYVT 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stam	NP_477448.1	VHS_STAM	10..154	CDD:239625	19/78 (24%)
		SH3_STAM	235..288	CDD:212754	25/53 (47%)
		GAT	340..412	CDD:281166
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	18/59 (31%)
		SH2_Grb2_like	56..149	CDD:199828	13/110 (12%)
		SH3_GRB2_like_C	156..208	CDD:212739	25/52 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R571
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.030