Protein Alignment Stam and Tom1l2

DIOPT Version :10

• Sequence 1: NP_477448.1
• Gene: Stam / 34505
• FlyBaseID: FBgn0027363
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: XP_006246568.1
• Gene: Tom1l2 / 360537
• RGDID: 1306728
• Length: 528
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 110/543 - (20%)
• Similarity: 214/543 - (39%)
• Gaps: 112/543 - (20%)

  Fly     7 SSPFDADVEKATSETNTNDNWSLILDVCDKVTTNPRLAKDCLKAVMRRM-GHTDPHVVMQAITLL 70
            |:|....:||||..:..:::|:|.:::||.:.......||.::|:.:|: |:.:...||.|:|:|
  Rat    10 STPVGQCLEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLSGNRNYREVMLALTVL 74

  Fly    71 DALSNNCGKPLHLEVASRDF-ETEFRRLLA-KAQPK--VSLKMRQVLKNWAENDYKNDRELDLIP 131
            :....|||...||.||:||| ::...|::: |..|.  |..|:..:::.||: .:::..:|..:.
  Rat    75 ETCVKNCGHRFHLLVANRDFIDSVLVRIISPKNNPPTIVQDKVLALIQAWAD-AFRSSPDLTGVV 138

  Fly   132 ALYAKLRQEGYDFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSPKTG 196
            .:|.:|:::|.:|         .:|:..|..|    :.:.|:...::..|..:...:.:.....|
  Rat   139 HIYEELKRKGIEF---------PMADLDALSP----IHTPQRSVPEMDPAATIPRSQLQPRTTAG 190

  Fly   197 SVASTGTASAYPSLY-PSFAGTGSSAPSAEASSAPAPEPRKVRA------------------LYD 242
            |.:|. .|:.|.:|. |:.:.||....::|..:....|...||.                  ..|
  Rat   191 SYSSP-PAAPYSTLQAPALSVTGPITANSEQIARLRSELDIVRGNTKVMSEMLTEMVPGQEDSSD 254

  Fly   243 FEAAEENELTFFA------------------GEIIHVLDDSDPNW-----WKGYNQRGEGLFPSN 284
            .|..:|...|..|                  .|::||.||.:..:     ::.|.........||
  Rat   255 LELLQELNRTCRAMQHRIVELISRVSNEEVTEELLHVNDDLNNVFLRYERFERYRSGRSVQNASN 319

  Fly   285 FVTADLSVDPERLDINQQHKS------AAAAGQRELDS-AAALQQKTEAAAAAAAA----QPVE- 337
            .|.::::.| ..:|:.....:      .:.|....|.| .|.|...||:.:...::    :|.:
  Rat   320 GVLSEVTED-NLIDLGPGSPAVVSPMVGSTAPPSSLSSQLAGLDLGTESVSGTLSSLQQCKPQDG 383

  Fly   338 ---IDESKIDRLLHLLHEANPEDPSQDSDEMLQLE---QEVHQMGPLIDAELERVD---RKHAQL 393
               ..:::.:.|.........|||.........|:   |.....|...|::|:.:|   .....:
  Rat   384 FDMFAQTRGNSLAEQRKTVTYEDPQAVGGLASALDNRKQSSEMRGRGGDSDLQPIDSWLMTQGMI 448

  Fly   394 TQLSSDLVDAINLY-HTLMRDDRAAAGHFAAAAGGFMPGLAGFPGAALYGAPGYPAAGGFPPAQN 457
            ......::|.|.:: .|.::.|....|..:.....|:...|                   ..|:.
  Rat   449 PVAQPSVMDDIEVWLRTDLKGDDLEEGVTSEEFDKFLEERA-------------------KAAET 494

  Fly   458 YPGMHSMPYGPVPNPPTSAPSQA 480
            .|.:        |:|||.||:.|
  Rat   495 VPDL--------PSPPTEAPAPA 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stam	NP_477448.1	VHS_STAM	10..141	CDD:340770	38/135 (28%)
		SH3_STAM	235..288	CDD:212754	16/93 (17%)
		GAT_STAM	337..413	CDD:410593	13/86 (15%)
		PHA03247	<436..526	CDD:223021	9/45 (20%)
Tom1l2	XP_006246568.1	VHS_Tom1L2	12..148	CDD:340793	39/136 (29%)
		GAT_TM1L2	218..309	CDD:410585	14/90 (16%)