DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stam and Wdfy2

DIOPT Version :9

Sequence 1:	NP_477448.1	Gene:	Stam / 34505	FlyBaseID:	FBgn0027363	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	XP_006252239.1	Gene:	Wdfy2 / 305956	RGDID:	1307337	Length:	400	Species:	Rattus norvegicus

Alignment Length:	169	Identity:	33/169 - (19%)
Similarity:	63/169 - (37%)	Gaps:	50/169 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 SKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSPKTGSVASTGTASAYPSLYPSFAG 216
            |:.|...|..:||:..|:|..::     :.:.:.||.:.|             ..:||:|
  Rat    23 SQEVVNMAVIVPKEEGVISVSED-----RTVRVWLKRDSG-------------QYWPSIY----- 64

  Fly   217 TGSSAPSAEASSAPAPEPRKVR------ALYDFEAAEE-NELT---------------FFAGEII 259
              .:.||..:..:..||.|::.      .:.:|..:|: |::|               .|..|:.
  Rat    65 --HAMPSPCSCMSFNPETRRLSIGLDNGTISEFILSEDYNKMTPVKNYQAHQSRVTMVLFVLELE 127

  Fly   260 HVL---DDSDPNWWKGYNQRGEGLFPSNFVTADLSVDPE 295
            .||   .|....|....:.:..|.:.::.|.:.|..|.|
  Rat   128 WVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVE 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stam	NP_477448.1	VHS_STAM	10..154	CDD:239625	1/1 (100%)
		SH3_STAM	235..288	CDD:212754	13/77 (17%)
		GAT	340..412	CDD:281166
Wdfy2	XP_006252239.1	WD40	16..272	CDD:295369	33/169 (20%)
		WD40	18..394	CDD:225201	33/169 (20%)
		WD40 repeat	27..64	CDD:293791	10/54 (19%)
		WD40 repeat	72..132	CDD:293791	11/59 (19%)
		WD40 repeat	159..197	CDD:293791	3/8 (38%)
		WD40 repeat	203..240	CDD:293791
		WD40 repeat	245..283	CDD:293791
		FYVE_WDFY1_like	279..348	CDD:277258
		WD40 repeat	321..363	CDD:293791
		WD40	358..394	CDD:197651
		WD40 repeat	369..395	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334908
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930