Protein Alignment Stam and Stam

DIOPT Version :9

• Sequence 1: NP_477448.1
• Gene: Stam / 34505
• FlyBaseID: FBgn0027363
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_035614.1
• Gene: Stam / 20844
• MGIID: 1329014
• Length: 548
• Species: Mus musculus
• Alignment Length: 595
• Identity: 233/595 - (39%)
• Similarity: 321/595 - (53%)
• Gaps: 82/595 - (13%)

  Fly     1 MGIFGQSSPFDADVEKATSETNTNDNWSLILDVCDKVTTNPRLAKDCLKAVMRRMGHTDPHVVMQ 65
            |.:|. ::|||.||||||||.||.::|.||||:||||..:....||||:::|||:.|.||||.||
Mouse     1 MPLFA-TNPFDQDVEKATSELNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQ 64

  Fly    66 AITLLDALSNNCGKPLHLEVASRDFETEFRRLLAKAQPKVSLKMRQVLKNWAENDYKNDRELDLI 130
            |:|||.|..:||||..||||.||||.:|...:|.|..|||..|::.::..|.: ::|||.:|.||
Mouse    65 ALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTD-EFKNDPQLSLI 128

  Fly   131 PALYAKLRQEGYDFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSPKT 195
            .|:...|:::|..|..:|.:.::......|.:.|||..|::::||:|:||||||||||.:   :.
Mouse   129 SAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIELSLKEQR---QQ 190

  Fly   196 GSVASTGTASAYPSLYPSFAGTGSSAPSAEASSAPAPEPRKVRALYDFEAAEENELTFFAGEIIH 260
            .:..||        ||||         ::...:....|.|||||:|||||||:|||||.|||||.
Mouse   191 SAPVST--------LYPS---------TSNLLTNHQHEGRKVRAVYDFEAAEDNELTFKAGEIIT 238

  Fly   261 VLDDSDPNWWKGYNQRGEGLFPSNFVTADLSVDPERLDINQQHKSAAAAGQRELDSAAALQQKTE 325
            ||||||||||||...:|.||||||||||||:.:||.:...::              ........:
Mouse   239 VLDDSDPNWWKGETHQGVGLFPSNFVTADLTAEPEMIKTEKK--------------TVQFNDDVQ 289

  Fly   326 AAAAAAAAQPVEIDESKIDRLLHLLHEANPEDPSQDSDEMLQLEQEVHQMGPLIDAELERVDRKH 390
            ........:|..|||.|:|:||.:|...:|.|...|..|:|.||...||||||||.:||.:||||
Mouse   290 IETIEPEPEPAFIDEDKMDQLLQMLQSTDPSDNQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKH 354

  Fly   391 AQLTQLSSDLVDAINLYHTLMRDD---------RAAAGHFAAAAGGFMPGLAGFPGAALYGAPGY 446
            ::|::|:..:::|::||..||.:|         ::...:..::|   :.....:||.|..|.  |
Mouse   355 SELSELNVKVMEALSLYTKLMNEDPMYSMYAKLQSQQYYLQSSA---VSASQVYPGPAQSGT--Y 414

  Fly   447 PAAG----------GFPPAQNYPGMHSMPYGPVPNPPTSA-PSQAPGA--PGGYLGQPQGQVPLP 498
            ..||          ..||.|    :.|:..|.||:....| |||...|  |...:...||. ..|
Mouse   415 LVAGSAQMTHLQSYSLPPEQ----LSSISQGAVPSSANQALPSQQTQASYPNAMVSSVQGN-SYP 474

  Fly   499 YQNGHAAQMNSLPAHLTQPTGTAPMPQPIYTQPTPVTTQQQQQP-LPQHPQQP------PQQQGQ 556
            .|    |.:.|.||........|.:|.|:   |..||..|...| :.|.|...      ||..|.
Mouse   475 SQ----ASIYSPPAAAAAAAAAAVVPVPV---PADVTIYQNAGPTMSQVPNYTLTSSTLPQTGGS 532

  Fly   557 QPPQHPQNSY 566
            |.|..||.:|
Mouse   533 QQPPQPQQAY 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stam	NP_477448.1	VHS_STAM	10..154	CDD:239625	71/143 (50%)
		SH3_STAM	235..288	CDD:212754	43/52 (83%)
		GAT	340..412	CDD:281166	33/71 (46%)
Stam	NP_035614.1	VHS_STAM	9..142	CDD:239625	69/132 (52%)
		SH3_STAM1	213..267	CDD:212897	29/53 (55%)
		GAT	306..377	CDD:281166	19/70 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	436..458		10/31 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	517..548		9/31 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831183
Domainoid	1	1.000	148	1.000	Domainoid score	I4445
eggNOG	1	0.900	-	-		E1_KOG2199
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	364	1.000	Inparanoid score	I2155
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52024
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002740
OrthoInspector	1	1.000	-	-		otm43863
orthoMCL	1	0.900	-	-		OOG6_103033
Panther	1	1.100	-	-	O	PTHR45929
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R571
SonicParanoid	1	1.000	-	-		X1427
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.790