Protein Alignment Stam and Stam

DIOPT Version :10

• Sequence 1: NP_477448.1
• Gene: Stam / 34505
• FlyBaseID: FBgn0027363
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_001408022.1
• Gene: Stam / 20844
• MGIID: 1329014
• Length: 555
• Species: Mus musculus
• Alignment Length: 602
• Identity: 233/602 - (38%)
• Similarity: 321/602 - (53%)
• Gaps: 89/602 - (14%)

  Fly     1 MGIFGQSSPFDADVEKATSETNTNDNWSLILDVCDKVTTNPRLAKDCLKAVMRRMGHTDPHVVMQ 65
            |.:|. ::|||.||||||||.||.::|.||||:||||..:....||||:::|||:.|.||||.||
Mouse     1 MPLFA-TNPFDQDVEKATSELNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQ 64

  Fly    66 AITLLDALSNNCGKPLHLEVASRDFETEFRRLLAKAQPKVSLKMRQVLKNWAENDYKNDRELDLI 130
            |:|||.|..:||||..||||.||||.:|...:|.|..|||..|::.::..|.: ::|||.:|.||
Mouse    65 ALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTD-EFKNDPQLSLI 128

  Fly   131 PALYAKLRQEGYDFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSPKT 195
            .|:...|:::|..|..:|.:.::......|.:.|||..|::::||:|:||||||||||.:   :.
Mouse   129 SAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIELSLKEQR---QQ 190

  Fly   196 GSVASTGTASAYPSLYPSFAGTGSSAPSAEASSAPAPEPRKVRALYDFEAAEENELTFFAGEIIH 260
            .:..||        ||||         ::...:....|.|||||:|||||||:|||||.|||||.
Mouse   191 SAPVST--------LYPS---------TSNLLTNHQHEGRKVRAVYDFEAAEDNELTFKAGEIIT 238

  Fly   261 VLDDSDPNWWKGYNQRGEGLFPSNFVTADLSVDPERLDINQQHKSAAAAGQRELDSAAALQQKTE 325
            ||||||||||||...:|.||||||||||||:.:||.:...::              ........:
Mouse   239 VLDDSDPNWWKGETHQGVGLFPSNFVTADLTAEPEMIKTEKK--------------TVQFNDDVQ 289

  Fly   326 AAAAAAAAQPVEIDESKIDRLLHLLHEANPEDPSQDSDEMLQLE-------QEVHQMGPLIDAEL 383
            ........:|..|||.|:|:||.:|...:|.|...|..|:|.||       ...||||||||.:|
Mouse   290 IETIEPEPEPAFIDEDKMDQLLQMLQSTDPSDNQPDLPELLHLEVYFLVILAMCHQMGPLIDEKL 354

  Fly   384 ERVDRKHAQLTQLSSDLVDAINLYHTLMRDD---------RAAAGHFAAAAGGFMPGLAGFPGAA 439
            |.:||||::|::|:..:::|::||..||.:|         ::...:..::|   :.....:||.|
Mouse   355 EDIDRKHSELSELNVKVMEALSLYTKLMNEDPMYSMYAKLQSQQYYLQSSA---VSASQVYPGPA 416

  Fly   440 LYGAPGYPAAG----------GFPPAQNYPGMHSMPYGPVPNPPTSA-PSQAPGA--PGGYLGQP 491
            ..|.  |..||          ..||.|    :.|:..|.||:....| |||...|  |...:...
Mouse   417 QSGT--YLVAGSAQMTHLQSYSLPPEQ----LSSISQGAVPSSANQALPSQQTQASYPNAMVSSV 475

  Fly   492 QGQVPLPYQNGHAAQMNSLPAHLTQPTGTAPMPQPIYTQPTPVTTQQQQQP-LPQHPQQP----- 550
            ||. ..|.|    |.:.|.||........|.:|.|:   |..||..|...| :.|.|...
Mouse   476 QGN-SYPSQ----ASIYSPPAAAAAAAAAAVVPVPV---PADVTIYQNAGPTMSQVPNYTLTSST 532

  Fly   551 -PQQQGQQPPQHPQNSY 566
             ||..|.|.|..||.:|
Mouse   533 LPQTGGSQQPPQPQQAY 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stam	NP_477448.1	VHS_STAM	10..141	CDD:340770	68/130 (52%)
		SH3_STAM	235..288	CDD:212754	43/52 (83%)
		GAT_STAM	337..413	CDD:410593	36/82 (44%)
		PHA03247	<436..526	CDD:223021	30/102 (29%)
Stam	NP_001408022.1	VHS_STAM1	9..139	CDD:340797	69/129 (53%)
		SH3_STAM1	213..267	CDD:212897	29/53 (55%)
		GAT_STAM1	301..384	CDD:410594	24/89 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	443..465		7/31 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	524..555		11/37 (30%)