Protein Alignment Stam and sem-5

DIOPT Version :9

• Sequence 1: NP_477448.1
• Gene: Stam / 34505
• FlyBaseID: FBgn0027363
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_509342.1
• Gene: sem-5 / 181055
• WormBaseID: WBGene00004774
• Length: 228
• Species: Caenorhabditis elegans
• Alignment Length: 240
• Identity: 63/240 - (26%)
• Similarity: 91/240 - (37%)
• Gaps: 73/240 - (30%)

  Fly    85 VASRDFETEFRRLLAKAQPKVSLKMRQVLK--NWAENDYKNDRELD----LIPALYAKLRQEGYD 143
            ||..||:       |.:..::|.|....||  |..|:.:....|||    .||:.|.::.:..:
 Worm     4 VAEHDFQ-------AGSPDELSFKRGNTLKVLNKDEDPHWYKAELDGNEGFIPSNYIRMTECNW- 60

  Fly   144 FKNLGDKTSKTVAEKAAALPKDPNV----------VSSQQE-------EDDIAK----------- 180
              .||    |.....|..|.|.|.|          .||..|       :|.:..
 Worm    61 --YLG----KITRNDAEVLLKKPTVRDGHFLVRQCESSPGEFSISVRFQDSVQHFKVLRDQNGKY 119

  Fly   181 ---AIEL-SLKENKGSPKTGSVASTGTASAYPSLYPSFAGTGSSAPSAEASSAPAPEPRKVRALY 241
               |::. ||.|.....:|.||:.|.|.                     ..|....|.:.|:||:
 Worm   120 YLWAVKFNSLNELVAYHRTASVSRTHTI---------------------LLSDMNVETKFVQALF 163

  Fly   242 DFEAAEENELTFFAGEIIHVLDDSDPNWWKGYNQRGEGLFPSNFV 286
            ||...|..||.|..|::|.:::..|||||:|......|:||||:|
 Worm   164 DFNPQESGELAFKRGDVITLINKDDPNWWEGQLNNRRGIFPSNYV 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stam	NP_477448.1	VHS_STAM	10..154	CDD:239625	19/74 (26%)
		SH3_STAM	235..288	CDD:212754	23/52 (44%)
		GAT	340..412	CDD:281166
sem-5	NP_509342.1	SH3_GRB2_like_N	2..53	CDD:212738	16/55 (29%)
		SH2_Grb2_like	56..151	CDD:199828	21/122 (17%)
		SH3_GRB2_like_C	158..210	CDD:212739	23/51 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R571
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.030