Protein Alignment Stam and TOM1L2

DIOPT Version :9

• Sequence 1: NP_477448.1
• Gene: Stam / 34505
• FlyBaseID: FBgn0027363
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_001337261.1
• Gene: TOM1L2 / 146691
• HGNCID: 11984
• Length: 536
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 80/358 - (22%)
• Similarity: 152/358 - (42%)
• Gaps: 81/358 - (22%)

  Fly     7 SSPFDADVEKATSETNTNDNWSLILDVCDKVTTNPRLAKDCLKAVMRRM-GHTDPHVVMQAITLL 70
            |:|....:||||..:..:::|:|.:::||.:.......||.::|:.:|: |:.:...||.|:|:|
Human    10 STPVGQCLEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLNGNRNYREVMLALTVL 74

  Fly    71 DALSNNCGKPLHLEVASRDFETEFRRLLAK-AQPK------VSLKMRQVLKNWAENDYKNDRELD 128
            :....|||...|:.||:|||   ...:|.| ..||      |..|:..:::.||: .:::..:|.
Human    75 ETCVKNCGHRFHILVANRDF---IDSVLVKIISPKNNPPTIVQDKVLALIQAWAD-AFRSSPDLT 135

  Fly   129 LIPALYAKLRQEGYDFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSP 193
            .:..:|.:|:::|.:|         .:|:..|..|    :.:.|:...::..|..:...:::...
Human   136 GVVHIYEELKRKGVEF---------PMADLDALSP----IHTPQRSVPEVDPAATMPRSQSQQRT 187

  Fly   194 KTGSVASTGTASAYPSLYPSFAGTGSSAPSAEASSAPAPEPRKVRALYDFEAAEENELTFFAGEI 258
            ..||.:|..     |:.|        |||.|.|.|...|    :.|..:..|...:||....|..
Human   188 SAGSYSSPP-----PAPY--------SAPQAPALSVTGP----ITANSEQIARLRSELDVVRGNT 235

  Fly   259 IHVLDDSDPNWWKGYNQRGEGLFPSNFVTADLSVDPERLDINQQHKSAAAAGQR--ELDSAAALQ 321
                        |..::....:.|....::||.:      :.:.:::..|..||  ||.|..:.:
Human   236 ------------KVMSEMLTEMVPGQEDSSDLEL------LQELNRTCRAMQQRIVELISRVSNE 282

  Fly   322 QKTEAAAAAAAAQPVEIDESKIDRLLHLLHEAN 354
            :.||                   .|||:..:.|
Human   283 EVTE-------------------ELLHVNDDLN 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stam	NP_477448.1	VHS_STAM	10..154	CDD:239625	40/151 (26%)
		SH3_STAM	235..288	CDD:212754	7/52 (13%)
		GAT	340..412	CDD:281166	4/15 (27%)
TOM1L2	NP_001337261.1	VHS_Tom1L2	12..148	CDD:340793	39/139 (28%)
		GAT_TM1L2	218..309	CDD:260096	20/116 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141247
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1213216at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850