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Protein Alignment Stam and STAM2

DIOPT Version :9

Sequence 1:	NP_477448.1	Gene:	Stam / 34505	FlyBaseID:	FBgn0027363	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_005834.4	Gene:	STAM2 / 10254	HGNCID:	11358	Length:	525	Species:	Homo sapiens

Alignment Length:	606	Identity:	223/606 - (36%)
Similarity:	304/606 - (50%)	Gaps:	130/606 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SSPFDADVEKATSETNTNDNWSLILDVCDKVTTNPRLAKDCLKAVMRRMGHTDPHVVMQAITLLD 71
            ::||:.||||||:|.||.::||||:|:||||.:.|..|||||||:|:|:.|..|||.:||:|||.
Human     6 ANPFEQDVEKATNEYNTTEDWSLIMDICDKVGSTPNGAKDCLKAIMKRVNHKVPHVALQALTLLG 70

  Fly    72 ALSNNCGKPLHLEVASRDFETEFRRLLA-KAQPKVSLKMRQVLKNWAENDYKNDRELDLIPALYA 135
            |...||||..||||.||||.||.|.::. ||.|||..|::.::..|:| :::.|.:..||.|...
Human    71 ACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSE-EFQKDPQFSLISATIK 134

  Fly   136 KLRQEGYDFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSPKTGSVAS 200
            .:::||..|...|.:|....|:...:..|:       :|::||||||||||:|.|..       .
Human   135 SMKEEGITFPPAGSQTVSAAAKNGTSSNKN-------KEDEDIAKAIELSLQEQKQQ-------H 185

  Fly   201 TGTASAYPSLYPSFAGTGSSAPSAEASSAPAPEPRKVRALYDFEAAEENELTFFAGEIIHVLDDS 265
            |.|.|.|||            ...:.::..|   |||||||||||.|:|||||..||||.|||||
Human   186 TETKSLYPS------------SEIQLNNKVA---RKVRALYDFEAVEDNELTFKHGEIIIVLDDS 235

  Fly   266 DPNWWKGYNQRGEGLFPSNFVTADLSVDPERLDINQQHKSAAAAGQRELDSAAALQQKTEAAAAA 330
            |.|||||.|.||.|||||||||.:|:::.|         :||......:|......:|:|
Human   236 DANWWKGENHRGIGLFPSNFVTTNLNIETE---------AAAVDKLNVIDDDVEEIKKSE----- 286

  Fly   331 AAAQPVEIDESKIDRLLHLLHEANPEDPSQDSDEMLQLEQEVHQMGPLIDAELERVDRKHAQLTQ 395
              .:||.|||.|:||.|.:|...:|.|...||.::|.||....||||:||.:||.:||||::|::
Human   287 --PEPVYIDEDKMDRALQVLQSIDPTDSKPDSQDLLDLEDICQQMGPMIDEKLEEIDRKHSELSE 349

  Fly   396 LSSDLVDAINLYHTLMRDDRAAAGHFAAAAGGFMPGLAGFPGAALYGAPGYPAAGGFPPAQNYPG 460
            |:..:::|:.||:.|:.:                             ||.|.......|..:||
Human   350 LNVKVLEALELYNKLVNE-----------------------------APVYSVYSKLHPPAHYP- 384

  Fly   461 MHSMPYGPVPN--PPTSAPSQAPGAPGGYLGQPQGQVPL-------PYQNGHAAQMNSLPAHL-- 514
                   |..:  |..:.|.|:.|  |.|:||...||.:       |.|.|   .:.|||.::
Human   385 -------PASSGVPMQTYPVQSHG--GNYMGQSIHQVTVAQSYSLGPDQIG---PLRSLPPNVNS 437

  Fly   515 ---TQP-------TGTAPMPQPIYTQP---------TPVTTQQQQQPLPQHPQQP-----PQQQG 555
               .||       ||...:..|.|...         |...|||....:.....|.     ||..|
Human   438 SVTAQPAQTSYLSTGQDTVSNPTYMNQNSNLQSATGTTAYTQQMGMSVDMSSYQNTTSNLPQLAG 502

  Fly   556 --QQPPQHP----QNSYHIDP 570
              ...|.||    ..:||..|
Human   503 FPVTVPAHPVAQQHTNYHQQP 523

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.