Protein Alignment Stam and stam2

DIOPT Version :9

• Sequence 1: NP_477448.1
• Gene: Stam / 34505
• FlyBaseID: FBgn0027363
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: XP_002936702.1
• Gene: stam2 / 100490315
• XenbaseID: XB-GENE-491139
• Length: 522
• Species: Xenopus tropicalis
• Alignment Length: 635
• Identity: 233/635 - (36%)
• Similarity: 317/635 - (49%)
• Gaps: 132/635 - (20%)

  Fly     1 MGIFGQSSPFDADVEKATSETNTNDNWSLILDVCDKVTTNPRLAKDCLKAVMRRMGHTDPHVVMQ 65
            |.:|| |:|||.||||||:|.||:::|.||:|:|||:...|..|||.|:::|:|:.|..|||.:|
 Frog     1 MPLFG-SNPFDQDVEKATNEYNTSEDWGLIMDICDKIVNTPNGAKDGLRSIMKRVNHKVPHVALQ 64

  Fly    66 AITLLDALSNNCGKPLHLEVASRDFETEFRRLLAKAQPKVSLKMRQVLKNWAENDYKNDRELDLI 130
            |:|||.|..:||||..|||:.||:|.:|.|.:::||.|||..|::.::..| |.:::.|.:..||
 Frog    65 ALTLLGASVSNCGKAFHLEICSREFASEVRGVISKAHPKVCDKLKALMVEW-EQEFQKDPQFSLI 128

  Fly   131 PALYAKLRQEGYDF-KNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSPK 194
            .|....|::||..| .:....||.|        ||:..:.:..:|||||||||||||:|:|..
 Frog   129 SATIKSLKEEGISFPSSTPQSTSNT--------PKNSALPAKSKEEDDIAKAIELSLQEHKQQ-- 183

  Fly   195 TGSVASTGTASAYPSLYPSFAGTGSSAPSAEASSAPAPEPRKVRALYDFEAAEENELTFFAGEII 259
                 ||.|.:.|||:              :|........|||||||||||.|:|||||.:||||
 Frog   184 -----STETKTLYPSV--------------DAQHDSQKMARKVRALYDFEAVEDNELTFKSGEII 229

  Fly   260 HVLDDSDPNWWKGYNQRGEGLFPSNFVTADLSVDPERLDINQQHKSAAAAGQRELDSAAALQQKT 324
            .||||||.|||||.|.||.||||||||::.|:::||.:                |:....|::..
 Frog   230 IVLDDSDANWWKGENHRGVGLFPSNFVSSSLNMEPEEV----------------LEKNPVLEEIP 278

  Fly   325 EAAAAAAAAQPVEIDESKIDRLLHLLHEANPEDPSQDSDEMLQLEQEVHQMGPLIDAELERVDRK 389
            | :|..|..:||.|||.|:|..|.||...:|.||..||..:|.||....||||:||..|:.:|||
 Frog   279 E-SAPKAEPEPVFIDEGKMDHALQLLQSIDPTDPKPDSSALLDLEDVCQQMGPMIDDRLQEIDRK 342

  Fly   390 HAQLTQLSSDLVDAINLYHTLMRDDRAAAGHFAAAAGGFMPGLAGFPGAALYGAPGYPAAGGFPP 454
            |::|::|:..:::|:.||:.||.:                        |.:|.....|.|.|
 Frog   343 HSELSELNVKVMEAVELYNKLMNE------------------------APMYSVYNKPQAQG--- 380

  Fly   455 AQNYPGMHSMPYGPVPNPPTSAPSQAPGAPGGYLGQPQGQV-----PLPYQ--NGHAAQMNSLPA 512
              :||...||         .|..|||.|  |.|:.|...||     |..|.  :.|...:.|||.
 Frog   381 --HYPAGVSM---------QSYHSQAQG--GSYMVQSMPQVQPATLPQGYSMASDHIGPLRSLPP 432

  Fly   513 HLTQPTGTAPMPQPIYTQPTPVTTQQQQQPLPQ--HP---------QQPPQQQGQQPPQHPQNSY 566
            .|.                :.||||..|.|.|.  |.         |..........|.:.|...
 Frog   433 TLN----------------STVTTQAAQPPYPSSGHDAVSNSPYLNQSSALHSAAGLPAYSQPMG 481

  Fly   567 HIDPQSQYAQVPPAVTQIQQPQQPPAPHAYMSPQHQQAPPPQGYQPGPNL 616
            .....|.|.....|:        ||. ::..:|.|..||.||.|...|.|
 Frog   482 MSSDASAYQNTTSAL--------PPG-YSVTAPLHSIAPQPQNYYQQPLL 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stam	NP_477448.1	VHS_STAM	10..154	CDD:239625	65/144 (45%)
		SH3_STAM	235..288	CDD:212754	43/52 (83%)
		GAT	340..412	CDD:281166	31/71 (44%)
stam2	XP_002936702.1	VHS_ENTH_ANTH	9..145	CDD:383016	63/136 (46%)
		SH3_STAM2	204..260	CDD:212896	43/55 (78%)
		PTZ00395	<376..>517	CDD:185594	46/181 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	150	1.000	Domainoid score	I4360
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68490
Inparanoid	1	1.050	358	1.000	Inparanoid score	I2168
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002740
OrthoInspector	1	1.000	-	-		otm49036
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1427
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.050