Protein Alignment aurB and TPK2

DIOPT Version :10

• Sequence 1: NP_477336.1
• Gene: aurB / 34504
• FlyBaseID: FBgn0024227
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: NP_015121.1
• Gene: TPK2 / 855898
• SGDID: S000006124
• Length: 380
• Species: Saccharomyces cerevisiae
• Alignment Length: 312
• Identity: 103/312 - (33%)
• Similarity: 157/312 - (50%)
• Gaps: 30/312 - (9%)

  Fly    11 RNHLPHLLAKVPEEHQEPIKNMCLKMMSHDAYGQPYDWSPRDFEMGAHLGRGKFGRVYLARERHS 75
            |.|...|.:::|::          .::|...|      :..||::...||.|.||||:|.|..|:
Yeast    44 RQHQQLLTSQLPQK----------SLVSKGKY------TLHDFQIMRTLGTGSFGRVHLVRSVHN 92

  Fly    76 HYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLK---HPHILRLLTWFHDESRIYLALEIASEGE 137
            ....|:||:.|:::.|   .:||....:.:..||   ||.::|:...|.|...|::.::....||
Yeast    93 GRYYAIKVLKKQQVVK---MKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGE 154

  Fly   138 LFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWSAH 202
            ||..||  .:.||..|.:..|..:|..||.|.|.:|:|:||||||||||.....:|:.|||: |.
Yeast   155 LFSLLR--KSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGF-AK 216

  Fly   203 TPNNKRRTLCGTLDYLPPEMVDGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRME 267
            .......|||||.||:.||::....|:.|||.|.||:|.||.:.|..||...:...||.||.:.:
Yeast   217 EVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGK 281

  Fly   268 ISYPSHLSKGCKELIGGLLRKESKGRITLV-----DVMTHYWVKAGMAEREL 314
            :.||.:......:|:..|:..:...||..:     |:..|.|....:.||.|
Yeast   282 VVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLL 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurB	NP_477336.1	STKc_Aurora	52..306	CDD:270909	94/261 (36%)
TPK2	NP_015121.1	STKc_PKA_like	69..358	CDD:270732	97/271 (36%)