Protein Alignment aurB and TPK3

DIOPT Version :10

• Sequence 1: NP_477336.1
• Gene: aurB / 34504
• FlyBaseID: FBgn0024227
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: NP_012755.1
• Gene: TPK3 / 853688
• SGDID: S000001649
• Length: 398
• Species: Saccharomyces cerevisiae
• Alignment Length: 305
• Identity: 99/305 - (32%)
• Similarity: 156/305 - (51%)
• Gaps: 29/305 - (9%)

  Fly    26 QEPIKNMCL----KMMSHDAYGQPYDWSPRDFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFK 86
            :|....:||    .:...|..|:   :|..||::...||.|.||||:|.|..|:....|:|.:.|
Yeast    60 EEASAGICLVKKPMLQYRDTSGK---YSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKK 121

  Fly    87 EELRKGCVQRQVLREIE-------IQSRLKHPHILRLLTWFHDESRIYLALEIASEGELFKHLRG 144
            ..:.|       |:::|       :.|.:.||.|:|:...|.|..::::.::....||||..||
Yeast   122 HTIVK-------LKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLR- 178

  Fly   145 APNHRFDEPRSAKYTYQVANALNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKRR 209
             .:.||..|.:..|..:|..||.|.|..::|:||||||||||.....:|:.|||::.:.| :...
Yeast   179 -KSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVP-DVTY 241

  Fly   210 TLCGTLDYLPPEMVDGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHL 274
            |||||.||:.||:|....|:.|||.|..|:|.||.:.|..||.:::|..||..|...|:.:|...
Yeast   242 TLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFF 306

  Fly   275 SKGCKELIGGLLRKESKGRITLV-----DVMTHYWVKAGMAEREL 314
            ....::|:..|:.::...|:..:     ||..|.|....:.|:.|
Yeast   307 HPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurB	NP_477336.1	STKc_Aurora	52..306	CDD:270909	91/265 (34%)
TPK3	NP_012755.1	STKc_PKA_like	86..376	CDD:270732	93/276 (34%)