Protein Alignment aurB and TPK1

DIOPT Version :10

• Sequence 1: NP_477336.1
• Gene: aurB / 34504
• FlyBaseID: FBgn0024227
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: NP_012371.2
• Gene: TPK1 / 853275
• SGDID: S000003700
• Length: 397
• Species: Saccharomyces cerevisiae
• Alignment Length: 311
• Identity: 107/311 - (34%)
• Similarity: 163/311 - (52%)
• Gaps: 30/311 - (9%)

  Fly    24 EHQEPIKNMCLKMMSHDAYGQ--------PYDWSPRDFEMGAHLGRGKFGRVYLARERHSHYLVA 80
            |.||..|...:...:.:.|.|        ...:|.:||::...||.|.||||:|.|.||:....|
Yeast    50 ETQEKPKQPHVTYYNEEQYKQFIAQARVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYA 114

  Fly    81 MKVMFKEELRKGCVQRQVLREIE-------IQSRLKHPHILRLLTWFHDESRIYLALEIASEGEL 138
            |||:.||.:.:       |:::|       :.|.:.||.|:|:...|.|..:|::.::....|||
Yeast   115 MKVLKKEIVVR-------LKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGEL 172

  Fly   139 FKHLRGAPNHRFDEPRSAKYTYQVANALNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWSAHT 203
            |..||  .:.||..|.:..|..:|..||.|.|..::|:||||||||||.....:|:.|||::.:.
Yeast   173 FSLLR--KSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV 235

  Fly   204 PNNKRRTLCGTLDYLPPEMVDGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEI 268
            | :...|||||.||:.||:|....|:.|:|.|..|||.||.:.|..||..::|..||.||...|:
Yeast   236 P-DVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAEL 299

  Fly   269 SYPSHLSKGCKELIGGLLRKESKGRITLV-----DVMTHYWVKAGMAEREL 314
            .:|...::..|:|:..|:.::...|:..:     ||..|.|.|..:.|:.|
Yeast   300 RFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLL 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurB	NP_477336.1	STKc_Aurora	52..306	CDD:270909	97/265 (37%)
TPK1	NP_012371.2	STKc_PKA_like	85..375	CDD:270732	100/276 (36%)