DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aurB and AUR3

DIOPT Version :9

Sequence 1:	NP_477336.1	Gene:	aurB / 34504	FlyBaseID:	FBgn0024227	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	NP_182073.1	Gene:	AUR3 / 819157	AraportID:	AT2G45490	Length:	288	Species:	Arabidopsis thaliana

Alignment Length:	276	Identity:	136/276 - (49%)
Similarity:	185/276 - (67%)	Gaps:	5/276 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 MCLKMMSHDAYGQPYDWSPRDFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQR 96
            |..|....||......||..|||:|..||:|||||||||||..|.|:||:||:|||::.|..:..
plant     1 MSKKSTESDAGNTEKQWSLADFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIHH 65

  Fly    97 QVLREIEIQSRLKHPHILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQ 161
            |:.||:|||:.|:||:||||..||||..||:|.||.|..|||:..|:  .|....|.::|.|...
plant    66 QLRREMEIQTSLRHPNILRLFGWFHDNERIFLILEYAHGGELYGVLK--QNGHLTEQQAATYIAS 128

  Fly   162 VANALNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKRRTLCGTLDYLPPEMVDGN 226
            ::.||.|||...|||||:||||:||.....||:||||||..: :|||:|:|||||||.||||:..
plant   129 LSQALAYCHGKCVIHRDIKPENLLLDHEGRLKIADFGWSVQS-SNKRKTMCGTLDYLAPEMVENR 192

  Fly   227 SYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYP--SHLSKGCKELIGGLLRKE 289
            .:|.:||.|.||||||||:.|.||||:.|.:.|:.:|.::::|:|  .::|:..|.||..||.|:
plant   193 DHDYAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAKNLISQLLVKD 257

  Fly   290 SKGRITLVDVMTHYWV 305
            ...|:::..:|.|.|:
plant   258 PSKRLSIEKIMQHPWI 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aurB	NP_477336.1	STKc_Aurora	52..306	CDD:270909	130/256 (51%)
AUR3	NP_182073.1	STKc_Aurora	21..274	CDD:270909	130/256 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68302
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D954262at2759
OrthoFinder	1	1.000	-	-		FOG0000946
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100573
Panther	1	1.100	-	-	O	PTHR24350
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X555
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.820