Protein Alignment aurB and PRKX

DIOPT Version :10

• Sequence 1: NP_477336.1
• Gene: aurB / 34504
• FlyBaseID: FBgn0024227
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: NP_005035.1
• Gene: PRKX / 5613
• HGNCID: 9441
• Length: 358
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 103/306 - (33%)
• Similarity: 163/306 - (53%)
• Gaps: 16/306 - (5%)

  Fly    20 KVPEEHQEPIKNMCLKMMSHDAYG-QPYDWSPRDFEMGAHLGRGKFGRVYLARERHSHYLVAMKV 83
            ||.||..:....:|   .|.:|.. :|..:|.:||:..|.:|.|.||||:|.:|:.:.:..|:||
Human    18 KVAEETPDGAPALC---PSPEALSPEPPVYSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKV 79

  Fly    84 MFKEELRKGCVQRQVLREIEIQSRLKHPHILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNH 148
            |...::.:...::.|..|..:...:.||.::||...:|||..:|:.:|....||||.:||.  ..
Human    80 MSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRN--RG 142

  Fly   149 RFDEPRSAKYTYQVANALNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKRRTLCG 213
            ||.......|:.::..|:.|.|...:::||||||||||.....:||.|||: |....::..||||
Human   143 RFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGF-AKKLVDRTWTLCG 206

  Fly   214 TLDYLPPEMVDGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGC 278
            |.:||.||::....:..:||.|.||||.:|.:.|.|||..::....|.||...:|.:|.||....
Human   207 TPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHV 271

  Fly   279 KELIGGLLRKESKGRITLV-----DVMTHYWVKA----GMAERELQ 315
            |:||..||..:...|:..:     ||..|.|.::    .:.:|:|:
Human   272 KDLIKKLLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLK 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aurB	NP_477336.1	STKc_Aurora	52..306	CDD:270909	92/258 (36%)
PRKX	NP_005035.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		5/18 (28%)
		STKc_PRKX_like	47..338	CDD:270763	94/274 (34%)